1. 分子生理研究系

1.1 神経機能素子研究部門

A. 英文原著

  1. Tateyama M & Kubo Y (2007) Coupling profile of the metabotropic glutamate receptor 1α is regulated by the C-terminal domain. Mol Cell Neurosci 34:445-452.
  2. Nakajo K & Kubo Y (2007) KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel. J Gen Physiol 130:269-281.
  3. Mio K, Kubo Y, Ogura T, Yamamoto T, Arisaka F & Sato C (2008) The motor protein prestin is a bullet-shaped molecule with inner cavities. J Biol Chem 283:1137-11145.

1.2 分子神経生理研究部門

A. 英文原著

  1. Hasegawa A, Naruse M, Hitoshi S, Iwasaki Y, Takebayashi H & Ikenaka K (2007) Regulation of glial development by cystatin C. J Neurochem 100:12-22.
  2. Ma J, Tanaka KF, Yamada G & Ikenaka K (2007) Induced expression of cathepsins and cystatin C in a murine model of demyelination. Neurochem Res 32:311-320.
  3. Ishii A, Ikeda T, Hitoshi S, Fujimoto I, Torii T, Sakuma K, Nakakita S, Hase S & Ikenaka K (2007) Developmental changes in the expression of glycogenes and the content of N-glycans in the mouse cerebral cortex. Glycobiology 17:261-276.
  4. Dromard C, Bartolami S, Deleyrolle L, Takebayashi H, Ripoll C, Simonneau L, Prome S, Puech S, Tran VB, Duperray C, Valmier J, Privat A & Hugnot JP (2007) NG2 and Olig2 expression provides evidence for phenotypic deregulation of cultured central nervous system and peripheral nervous system neural precursor cells. Stem Cells 25:340-353.
  5. Tanaka KF, Takebaysashi H, Yamazaki Y, Ono K, Naruse M, Iwasato T, Itohara S, Kato H & Ikenaka K (2007) Murine model of Alexander disease:analysis of GFAP aggregate formation and its pathological significance. Glia 55:617-631.
  6. Mo Z, Moore AR, Filipovic R, Ogawa Y, Ikenaka K, Antic SD & Zecevic N (2007) Human cortical neurons originate from radial glia and neuron-restricted progenitors. J Neurosci 27:4132-4145.
  7. Karpowicz P, Inoue T, Runciman S, Deveale B, Seaberg R, Gertsenstein M, Byers L, Yamanaka Y, Tondat S, Slevin J, Hitoshi S, Rossant J & van der Kooy D (2007) Adhesion is prerequisite, but alone insufficient, to elicit stem cell pluripotency. J Neurosci 27:5437-5447.
  8. Miyoshi G, Butt SJ, Takebayashi H & Fishell G (2007) Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors. J Neurosci 27:7786-7798.
  9. Hitoshi S, Maruta N, Higashi M, Kumar A, Kato N & Ikenaka K (2007) Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress. J Neurosci Res 85:3574-3585.
  10. Ishii A, Ikenaka K & Pfeiffer SE (2007) The N-glycan profile of mouse myelin, a specialized central nervous system membrane. J Neurochem 103:25-31.
  11. Langer D, Ikehara Y, Takebayashi H, Hawkes R & Zimmermann H (2007) The ectonucleotidases alkaline phosphatase and NTPDase2 are associated with subsets progenitor cell populations in the mouse embryonic, postnatal and adult neurogenic zones. Neuroscience 150:863-879.
  12. Sasaki N, Okishio K, Ui- Tei K, Saigo K, Kinoshita-Toyoda A, Toyoda H, Nishimura T, Suda Y, Hayasaka M, Hanaoka K, Hitoshi S, Ikenaka K & Nishihara S (2007) Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells. J Biol Chem (in press).

D. 研究関係著作

  1. 田中謙二, 李海雄, 池中一裕 (2007) 特集 情報伝達処理におけるグリアの機能と異常 グリア細胞機能異常動物の開発. Brain Nerve 55:747-753.

1.3 細胞内代謝研究部門

A. 英文原著

  1. Chen L, Miyamoto Y, Furuya K, Mori N & Sokabe M (2007) PREGS Induces LTP in the Hippocampal Dentate Gyrus of Adult Rats via the Tyrosine Phosphorylation of NR2B Coupled to ERK/CREB Signaling. J Neuropysiol 98:1538-1548.
  2. Dai S, Chen L & Sokabe M (2007) Neurosteroid Estradiol Rescues Ischemia-Induced Deficit in the Long-Term Potentiation in rat hippocampal CA1 neurons. Neuropharmacol 52:1124-1138 .
  3. Miyashita T, Tatsumi H, Hayakawa K, Mori N & Sokabe M (2007) Quantitative estimation of Na+ K+ ATPase activity in the Endolymphati Sac Epithelial Cells of Guinea-Pig. Pflügers Arch 453:905-913.
  4. Toyota M, Furuichi T, Tatsumi H & Sokabe M (2007) Hypergravity stimulation induces intracellular calcium transients in Arabidopsis seedlings. Adv Space Res 39:1190-1197.
  5. Hirata H, Tatsumi H & Sokabe M (2007) Dynamics of Actin Filaments during Tension-Dependent Formation of Actin Bundles. Biochim Biophys Acta 1770:1115-1127.
  6. Nakayama Y, Fujiu K, Sokabe M & Yoshimura K (2007) Mechanosensitive channel with a latch mechanism is present in the cytoplasm and chloroplast of Chlamydomonas. Proc Natl Acad Sci USA 104:5883-5888.
  7. Nakagawa Y, Katagiri T, Shinozaki K, Qi Z, Tatsum H, Furuichi T, Kishigami A, Sokabe M, Sato S, Kato T, Tabata S, Kojima I, Iida K, Terashima A, Ikeda M, Yamanaka T & Iida H (2007) Stretch-activated calcium channel component required for touch sensing in Arabidopsis roots. Proc Natl Acad Sci USA 104:3639-3644 .
  8. Shi F, Chiu YJ, Cho Y, Sokabe M & Fujiwara K (2007) Down-regulation of ERK- But Not MEK-Phosphorylation in Cultured Endothelial Cells by Repeated Changes in Cyclic Stretch. Cardiovas Res 73:813-822.
  9. Nakanishi M, Mori T, Nishikawa K, Sawada M, Kuno M & Asada A (2007) The effects of general anesthetics on P2X7 and P2Y receptors in a rat microglial cell line. Anesthesia Analgesia 104:1136-1144.
  10. Nomura T, Sokabe M & Yoshimura K (2007) Interaction between the cytoplasmic and transmembrane domains of the mechanosensitive channel, MscS. Biophys J (in press).
  11. Hayakawa K, Tatsumi H & Sokabe M (2007) Stress fiber acts as a force-transmitting and -focusing structure to activate MS channels in endothelial cells. J Cell Sci (in press).
  12. Toyota M, Furuichi T, Tatsumi H & Sokabe M (2007) Cytoplasmic calcium increases in response to changes in the gravity vector in hypocotyls and petioles of Arabidopsis seedling. Plant Physiol (in press).
  13. Mizoguchi F, Mizuno A, Hayata T, Nakashima K, Heller S, Ushida T, Sokabe M, Miyasaka N, Suzuki M, Ezura Y & Noda M (2007) Transient Receptor Potential Vanilloid 4 Deficiency Suppresses Unloading-Induced Bone Loss. J Cell Physiol (in press)
  14. Ito S, Kume H, Naruse K, Kondo M, Takeda N, Iwata S, Hasegawa Y & Sokabe M (2007) A novel Ca2+ influx pathway activated by mechanical stretch in human airway smooth muscle cells. Am J Respir Cell Mol Biol (in press).
  15. Hirano Y, Ishiguro N, Sokabe M, Takigawa M, & Naruse K (2008) Effects of tensile and compressive strains on response of a chondrocytic cell line embedded in type I collagen gel. J Biotechnol 133:245-252.
  16. Morihata H, Kawawaki J, Okina M, Sakai H, Notomi T, Sawada M, & Kuno M (2008) Early and late activation of the voltage-gated proton channel during lactic acidosis through pH-dependent and -independent mechanisms. Pflugers Arhciv 455:829-838.

D. 研究関係著作

  1. Furuichi T, Kawano T, Tatsumi H & Sokabe M (2007) Roles of Ion Channels in Environmental Responses of Plants. “Sensing with Ion Channels” (Ed. Martinac B), Springer-Verlag, Berlin, pp 47-67.
  2. Lim CT, Rajagopal G, Hunziker W, Lane B & Sokabe M (2007) Role of external mechanical forces in cell signal transduction. “Biomechanics at Micro- and Nanoscale Levels, III” (Ed. Wada H), World Sci Pub, Singapore, pp 80-104.
  3. Hirata H, Tatsumi H & Sokabe M (2007) Biophysical mechanisms of tension-dependent formation of stress fibers from actin meshwork. “Biomechanics at Micro- and Nanoscale Levels, IV” (Ed. Wada H), World Sci Pub, Singapore, pp 72-81.
  4. 吉村健二郎, 野村健 & 曽我部正博 (2007) 細胞メカノセンサーの実体と機能. 日本物理学会誌 62:9-15.
  5. 曽我部正博 (2007) 細胞はどのようにして“力”を感じるのか:細胞力覚の多様性. Medical Bio 9:32-39.
  6. 曽我部正博 (2007) 器官のサイズは力学で決まる? (訳) / 細胞のメカノセンサーとメカノバイオロジーの黎明 (解説). Parity(パリティ)09:37-41.
  7. 曽我部正博 & 陳玲 (2007) シナプス可塑性に対するアミロイドβと神経ステロイドの効果:標的分子と作用機序の解析. PharmaVISION NEWS 10:6-11.
  8. 曽我部正博 (2007) 機械刺激受容チャネル. “生物物理学ハンドブック” (石渡他 編), 朝倉書店,東京,pp 276-278.