伊佐研ＨＰ-業績リスト

Publications
	(Original papers) 1. Isa T, Kurosawa M, Sato A, Swenson RS (1985) Reflex responses evoked in the adrenal sympathetic nerve to electrical stimulation of somatic afferent nerves in the rat. Neuroscience Research 3:130-144. 2. Isa T, Itouji T, Sasaki S (1988) Excitatory pathways from Forel's field H to head elevator motoneurones in the cat. Neuroscience Letters 90 :89-94. 3. Isa T, Itouji T, Nakao S, Sasaki S (1988) Subtypes of neurones in Forel's field H as defined by their axonal projection. Neuroscience Letters 90:95-99. 4. Isa T, Sasaki S (1988) Effects of lesion of paramedian pontomedullary reticular formation by kainic acid injection on the visually triggered horizontal head movements in cat. Neuroscience Letters 87: 233-239. 5. Alstermark B, Isa T, Lundberg A, Pettersson L-G, Tantisira B (1989) The effect of low pyramidal lesions on forelimb movements in the cat. Neuroscience Research 7: 71-75. 6. Alstermark B, Isa T, Kummel H, Tantisira B (1990) Projection from excitatory C3-C4 propriospinal neurones to lamina VII and VIII neurones in the C6-Th1 segments of the cat. Neuroscience Research 8:131-137. 7. Alstermark B, Isa T, Tantisira B (1990) Projection from excitatory C3-C4 propriospinal neurones to spinocerebellar and spinoreticular neurones in the C6-Th1 segments of the cat. Neuroscience Research 8: 124-130. 8. Isa T, Pettersson L-G (1991) Effect of naloxone on transmission in excitatory and inhibitory spinal reflex pathways. Neuroscience Research 12:388-391. 9. Alstermark B, Isa T, Tantisira B (1991) Integration in descending motorpathways controlling the forelimb in the cat. 18. Morphology, axonal projection and termination of collaterals from C3-C4 propriospinal neurones in the segment of origin. Experimental Brain Research 88:561-568. 10. Alstermark B, Isa T, Tantisira B (1991) Pyramidal excitation in long propriospinal neurones in the cervical segments of the cat. Experimental Brain Research 84:569-582. 11. Isa T, Sasaki S (1992) Descending projections from Forel's field H neurones to the brain stem and the upper cervical spinal cord in the cat. Experimental Brain Research 88:563-579. 12. Isa T, Sasaki S (1992) Mono- and disynaptic pathways from Forel's field H to dorsal neck motoneurones in the cat. Experimental Brain Research 88:580- 593. 13. Isa T, Itouji T (1992) Axonal trajectories of single Forel's field H neurones in the mesencephalon, pons and medulla oblongata in the cat. Experimental Brain Research 89:484-495. 14. Alstermark B, Isa T, Lundberg A, Pettersson L-G, Tantisira B (1993) Characteristics of target reaching in cats. II. Reaching to targets at different locations. Experimental Brain Research 94:287-294. 15. Isa T, Naito K (1994) Activity of neurons in Forel's field H during orienting head movements in alert head-free cats. Experimental Brain Research 100:187-199. 16. Isa T, Naito K (1995) Activity of neurons in the medial pontomedullary reticular formation during orienting movements in alert head-free cats. Journal of Neurophysiology 74 : 73-95. 17. Isa T, Iino M, Itazawa S, Ozawa S (1995) Spermine mediates inward rectification of Ca2+- permeable AMPA receptor channels. Neuroreport 6:2045-2048. 18. Isa T, Itazawa S, Iino M, Tsuzuki K, Ozawa S (1996) Distribution of neurones expressing inwardly rectifying and Ca2+-permeable AMPA receptors in rat hippocampal slices. Journal of Physiology. (London) 491 : 719 - 733. 19. Iino M, Koike M, Isa T, Ozawa S (1996) Voltage dependent blockage of Ca2+- permeable AMPA receptors by Joro spider toxin in cultured rat hippocampal neurones. Journal of Physiology (London) 496: 431-437. 20. Tantisira B, Alstermark B, Isa T, Kummel H, Pinter M (1996) Motoneuronal projection pattern of single C3-C4 propriospinal neurones. Canadian Journal of Physiology & Pharmacology 74:518-530. 21. Isa T, Iino M, Ozawa S (1996) Spermine blocks synaptic transmission mediated by Ca2+- permeable AMPA receptors. Neuroreport 7: 689-692. 22. Itazawa S, Isa T, Ozawa S (1997) Inwardly rectifying and Ca2+- permeable AMPA-type glutamate receptor channels in rat neocortical neurons. Journal of Neurophysiology, 78:2592-2601. 23. Pettersson L-G, Lundberg A, Alstermark B, Isa T, Tantisira B (1997) Effect of spinal cord lesions on forelimb target-reaching and on visually guided switching of target-reaching in the cat. Neuroscience Research, 29:241-256. 24. Isa T, Endo T, Saito Y (1998) The visuo-motor pathway in the local circuit of the rat superior colliculus. Journal of Neuroscience 18: 8496-8504. 25. Aizawa H, Kobayashi Y, Yamamoto M, Isa T (1999) Injection of nicotine into the superior colliculus facilitates occurrence of express saccades in monkeys. Journal of Neurophysiology 82: 1642-1646. 26. Saito Y, Isa T (1999) Electrophysiological and morphological properties of neurons in the rat superior colliculus. I. Neurons in the intermediate layer. Journal of Neurophysiology 82: 754-767. 27. Sasaki S, Isa T, Naito K (1999) Effects of lesion of pontomedullary reticular formation on visually triggered vertical and oblique head orienting movements in alert cats. Neuroscience Letters. 265: 13-16. 28. Alstermark B, Isa T, Ohki Y, Saito Y. (1999) Disynaptic pyramidal excitation in forelimb motoneurons mediated via C3-C4 propriospinal neurons in the macaca fuscata. Journal of Neurophysiology, 82: 3580-3585. 29. Saito Y, Isa T (2000) Voltage-gated transient outward currents neurones with different firing properties in rat superior colliculus. Journal of Physiology (London), 528: 91-105. 30. Tsuzuki K, Isa T, Ozawa S (2000) Subunit composition of AMPA receptors expressed by single hippocampal neurons. Neuroreport 11:3583-3587. 31. Endo T, Isa T (2001) Functionally different AMPA-type glutamate receptors in morphologically identified neurons in superficial layer of rat superior colliculus. Neuroscience, 108: 129-141. 32. Kobayashi Y, Inoue Y, Yamamoto M, Isa T, Aizawa H (2002) Contribution of pedunculopontine tegmental nucleus neurons to performance of visually guided saccade tasks in monkeys. Journal of Neurophysiology, 88:715-731. 33. EndoT, Isa T (2002) Postsynaptic and presynaptic GABAB receptor-mediated inhibition in rat superficial superior colliculus neurons. Neuroscience Letters 322: 126-130. 34. Saito Y, Isa T (2003) Local excitatory network and NMDA receptor activation generate a synchronous and non-linear bursting command from the superior colliculus. Journal of Neuroscience, 23:5854-5864. 35. Katsuta H, Isa T (2003) Release from GABAA receptor-mediated inhibition unmasks interlaminar connection within superior colliculus in anesthetized adult rats. Neuroscience Research, 46:73-83. 36. Yamashita T, Isa T (2003) Fulfenamic acid sensitive, Ca2+-dependent inward current induced by nicotinic acetylcholine receptors in dopamine neurons. Neuroscience Research, 46:463-473. 37. Endo T, Yanagawa Y, Obata K, Isa T (2003) Characteristics of GABAergic neurons in the superficial superior colliculus. Neuroscience Letters, 346:81-84. 38. Yamashita T, Isa T (2003) Ca2+-dependent inward current induced by nicotinic receptor activation depends on Ca2+/calmodulin-CaMKII pathway in dopamine neurons. Neuroscience Research, 47: 225-232. 39. Saitoh K, Hattori S, Song W-J, Isa T, Takakusaki K (2003) Nigral GABAergic inhibition upon cholinergic neurons in the rat pedunculopontine tegmental nucleus. European Journal of Neuroscience, 18: 879-886. 40. Alstermark B, Ogawa J, Isa T (2004) Lack of monosynaptic corticomotoneuronal excitation in the adult rat: fast disynaptic excitation is mediated via reticulospinal neurones and slow polysynaptic excitation via segmental interneurons. Journal of Neurophysiology, 91:1832-1839. 41. Yamashita T, Isa T (2004) Enhancement of excitatory postsynaptic potentials by preceding application of acetylcholine in mesencephalic dopamine neurons. Neuroscience Research 49: 91-100. 42. Sakatani T, Isa T (2004) PC-based high-speed video-oculography for measuring rapid eye movements in mice. Neuroscience Research, 49:123-131. 43. Tanaka H, Ono K, Shibasaki H, Isa T, Ikenaka K (2004) Conduction properties of identified neural pathways in the central nervous system of mice in vivo. Neuroscience Research, 49:113-122. 44. Saitoh K, Isa T, Takakusaki K (2004) Nigral GABAergic inhibition upon mesencephalic dopaminergic cell groups in rats. European Journal of Neuroscience, 19:2399-2409. 45. Saito Y, Isa T (2004) Laminar specific distribution of lateral excitatory connections in the rat superior colliculus. Journal of Neuophysiology, in press. 46. Sasaki S, Isa T, Pettersson L-G, Alstermark B, Naito K, Yoshimura K, Seki K, Ohki Y (2004) Dexterous finger movements in primate without monosynaptic corticomotoneuronal excitation. Journal of Neurophysiology, 92:3142-3147. 47.Li F, Endo T, Isa T (2004) Presynaptic muscarinic acetylcholine receptors suppress GABAergic synaptic transmission in the intermediate gray layer of mouse superior colliculus. European Journal of Neuroscience, 20:2079-2088. 48. Sasaki S, Naito K, Yoshimura K, Isa T, Seki K, Pettersson LG, Alstermark B & Ohki Y (2004) Cortico-motoneuronal system and dexterous finger movements. Journal of Neurophysiology 92:3601-3603. 49. Watanabe M, Kobayashi Y, Inoue Y, Isa T (2005) Effects of local nicotinic activation of the superior colliculus on saccades in monkeys. Journal of Neurophysiology, 93: 519-534. 50. Saito Y, Isa T (2005) Organization of interlaminar interactions in the rat superior colliculus. Journal of Neurophysiology, 93:2898-2907. 51. Sooksawate T, Saito Y, Isa T (2005) Electrophysiological and morphological properties of identified crossed tecto-reticular neurons in the rat superior colliculus. Neuroscience Research, 52:174-184. 52. Endo T, Yanagawa Y, Obata K, Isa T (2005) Nicotinic acetylcholine receptor subtypes involved in facilitation of GABAergic inhibition in mouse superficial superior colliculus. Journal of Neurophysiology, 94: 3893-3902. 54. Isa T, Ohki Y, Seki K, Alstermark B (2006) Properties of propriospinal neurons in the C3-C4 segments mediating disynaptic pyramidal excitation to forelimb motoneurons in the macaque monkey. Journal of Neurophysiology, 95: 3674-3685. 55. Tanaka H, Ikenaka K, Isa T (2006) Electrophysiological abnormalities precede apparent histological demyelination in the central nervous system of mice overexpressing proteolipid protein. Journal of Neuroscience Research 84: 1206-1216. 56. Sooksawate T, Isa T (2006) Properties of cholinergic responses in neurons in the intermediate gray layer of rat superior colliculus. European Journal of Neuroscience, 24: 3096-3108. 57. Lee PH, Sooksawate T, Yanagawa Y, Isa K, Isa T, Hall WC (2007) Identity of a pathway for saccadic suppression. Proceedings of National Academy of Sciences, USA 104: 6824-6827. * = equal contribution, **= co-corresponding authors 58. Sakatani T, Isa T (2007) Quantitative analysis of saccade-like rapid eye movements in C57BL/6 mice. Neuroscience Research 58: 324-331. 59. Nishimura Y, Onoe T, Morichika Y, Tsukada H, Isa T (2007) Activation of parieto-frontal stream during reaching and grasping studied by positron emission tomography in monkeys. Neuroscience Research, 59: 243-250. 60. Sato A, Nishimura Y, Oishi T, Higo N, Murata Y, Onoe H, Saito K, Tsuboi F, Takahashi M, Isa T, Kojima T (2007) Differentially expressed genes among motor and prefrontal areas of macaque neocortex. Biochemical and Biophysical Research Communications, 362: 665-669. 61. Nishimura Y, Onoe T, Morichika Y, Perfiliev S, Tsukada H, Isa T (2007) Time-dependent central compensatory mechanism of finger dexterity after spinal-cord injury. Science, 318: 1150-1155. 62. Kaneda K, Phongphanphanee P, Katoh T, Isa K, Yanagawa Y, Obata K, Isa T (2008) Regulation of burst activity through pre- and postsynaptic GABAB receptors in mouse superior colliculus. Journal of Neuroscience, 28:816-827. 63. Endo T, Tarusawa E, Notomi T, Kaneda K, Hirabayashi M, Shigemoto R, Isa T (2008) Dendritic Ih ensures high-fidelity spike responses of motion sensitive neurons in rat superior colliculus. Journal of Neurophysiology, 99: 2066-2076. 64. Phongphanphanee P, Kaneda K, Isa T (2008) Spatio-temporal profiles of field potentials in mouse superior colliculus analyzed by multichannel recording. Journal of Neuroscience, 28: 9309-9318. 65. Sooksawate T, Isa K, Isa T (2008) Cholinergic responses in crossed tecto-reticular neurons of rat superior colliculus. Journal of Neurophysiology, 100: 2702-2711. 66. Yoshida M, Takaura K, Kato R, Ikeda T, Isa T (2008) Striate cortical lesions affect deliberate decision and control of saccade: implication for blindsight. Journal of Neuroscience, 28: 10517-10530. 67. Kaneda K, Isa K, Yanagawa Y, Isa T (2008) Nigral inhibition of GABAergic neurons in mouse superior colliculus. Journal of Neuroscience, 28: 11071-11078. 68. Nishimura Y, Morichika Y, Isa T (2009) A common subcortical oscillatory network contributes to recovery after spinal cord injury. Brain,132: 709-721. 69. Okada K, Toyama K, Inoue Y, Isa T, Kobayashi Y (2009) Different pedunculopontine tegmental neurons signal predicted and actual task rewards. Journal of Neuroscience, 29: 4858-4870. 70. Tanaka H, Tanaka K, Ma J, Isa T, Tanda K, Miyakawa T, Suzuki A, Ishibashi T, Baba H, Shigemoto R, Ono K, Ikenaka K (2009) Mice with altered myelin proteolipid protein gene expression show schizophrenia-related behavior accompanied by abnormal neuron-glial interaction and conduction velocity. Journal of Neuroscience, 29: 8363-8371. 71. Higo N, Nishimura Y, Murata Y, Oishi T, Saito K, Takahashi M, Tsuboi F, Isa T (2009) Increased expression of the growth-associated protein-43 gene in the sensorimotor cortex of the macaque monkey after lesioning of the lateral corticospinal tract. Journal of Comparative Neurology, 516: 493-506. 72. Takahashi M, Vattanajun A, Umeda T, Isa K, Isa T (2009) Large-scale reorganization of corticofugal fibers after neonatal hemidecortication for functional restoration of forelimb movements. European Journal of Neuroscience, in press. (Review Articles) 1. Isa T, Itouji T, Sasaki S (1992) Control of head movement in the cat: two separate pathways from the superior colliculus to neck motoneurones and their roles in orienting movements. In: "Vestibular and brain stem control of eye, head and body movements." (eds) Shimazu H & Shinoda Y, Jpn. Scientific Society Press, pp275-284. 2. Isa T, Itouji T, Sasaki S (1992) Control of vertical head movement via Forel's field H. In : "The Head-Neck Sensory Motor System" (eds) Berthoz A, Graf W& Vidal PP, Oxford Univ. Press, Chapter 52, pp345-350. 3. Isa T, Itouji T, Naito K, Sasaki S (1993) Control of head movements during orienting and visual discrimination. Biomedical Research 14, Suppl 1, 47-49. 4. Ozawa S, Isa T, Tsuzuki K, Iino M (1996) Ca2+ permeability and subunit composition of AMPA receptors in hippocampal neurons. In : "Integrative and Molecular Approach to Brain Function." (eds) Ito M, Miyashita Y, Elsevier, Amsterdam, pp47-56. 5. Isa T, Sasaki S (1999) Neural mechanisms for the control of visually guided orienting movements of the head. In : “Motor Control Today and Tomorrow (ed. G.N. Gantchev, S. Mori, J. Massion, Academic Publishing House “Prof. M. Drinov, Sofia)”, pp57 - 69. 6. Isa T (1999) A role of brainstem acetylcholinergic system in regulating initiation of saccadic eye movements. In : “From Basic Motor Control to Functional Recovery” (eds. N. Gantchev & G.N. Gantchev), pp19－23. 7. Kobayashi Y, Saito Y, Isa T (2001) Facilitation of saccade initiation by brainstem cholinergic system. Brain Development, 23 S24-S27. 8. Isa T, Saito Y (2001) The direct visuo-motor pathway in mammalian superior colliculus; novel perspective on the interlaminar connection. Neuroscience Research, (update article) 41: 107-113. 9. Isa T, Sasaki S (2002) Brainstem control of head movements during orientation; organization of the premotor circuits. Progress in Neurobiology, 66: 205-241. 10. Alstermark B, Isa T (2002) Premotoneuronal and direct corticomotoneuronal control in the cat and macaque monkey. In “Movement and Sensation” (eds. Gandevia S, Proske U), Adv Exp Med Biol. 2002;508:281-297. 11. Kobayashi Y, Isa T (2002) Sensory-motor gating and cognitive control by the brainstem cholinergic system. Neural Networks 15:731-741. 12. Isa T (2002) Intrinsic processing in the mammalian superior colliculus. Current Opinion in Neurobiology, 12:668-677. 13. Isa T, Kobayashi Y, Saito Y (2003) Dynamic modulation of signal transmission in the local circuit of mammalian superior colliculus. In “The Superior Colliculus: New Approaches for Studying Sensorimotor Integration.” (eds. W.C. Hall & A. K. Moschovakis), CRC Press, pp159-171. 14. Isa T & Kobayashi Y (2003) Switching between cortical and subcortical sensorimotor pathways. In Progress in Brain Research “Brain Mechanisms for the integration of posture and movement”. (eds. Mori S, Stuart DG, Wiesendanger M) 143:295-301. 15.Kobayashi Y, Inoue Y & Isa T (2003) Pedunculo-pontine control of visually guided saccades. In Progress in Brain Research “Brain Mechanisms for the integration of posture and movement”. (eds. Mori S, Stuart DG, Wiesendanger M) 143:439-445. 16. Isa T, Inoue Y, Kobayashi Y (2003) Cognitive function of the brainstem cholinergic system. In International Congress Series 1250 “Cognition and Emotion in the Brain” (eds. Ono t, Matsumoto G, Llinas R, Berthoz A, Norgren R, Nishijo H, Tamura R), pp397-406. 17. Isa T & Sparks D (2005) Microcircuit of the Superior Colliculus: A Neuronal Machine that Determines Timing and Endpoint of Saccadic Eye Movements. Background paper for 93rd Dahlem Workshop on Microcircuits; The interface between Neurons and Global Brain Function. 18. Kiehn, O., Buschges, A., Duch, C., Grillner, S., Isa, T., Lansner, A., Pfluger, H.-J., Richter, D.W., Sillar, K.T., smith, J.C., Sparks, D.L. (2006) Group report: Microcircuits in the motor system. “Microcircuits. The interface between neurons and global brain function.” (eds. S. Grillner & A.M. Graybiel), pp77-104, The MIT Press. 19. Alstermark, B. Isa, T., Pettersson, L-G., Sasaki, S (2007) The C3-C4 propriospinal system in the cat and monkey; a spinal premotoneuronal centre for voluntary motor control. Acta.Physiol. Scand., 189: 123-140. 20. Pettersson L.-G.., Alstermark, B., Blagovechtchenski, E., Isa, T., Sasaski, S(2007) Skilled digit movements in feline and primate ? descending control and motor recovery after spinal cord injuries. Acta Physiol. Scand., 189: 141-154. 21. Isa, T., Ohki, Y., Alstermark, B., Pettersson, L-G., Sasaki, S (2007) Direct and indirect cortico-motoneuronal pathways and control of hand/arm movements. Physiology, 22: 145-152. 22. Sakatani T, Isa T (2008) Superior colliculus and saccade generation in mice. In “Eyes, Retina and Visual System of the Mouse” (eds Calupa Leo.M. & Willliams R), MIT Press, pp233-244. 23. Isa T, Schwartz AB. (2008) Introduction. Current Opinion in Neurobiology, 18: 541-543. 24. Nishimura Y, Isa T (2009) Compensatory changes at the cerebral cortical level after spinal cord injury. The Neuroscientist, 15: 436-444. 25. Isa T, Schwartz AB. (2008) Introduction. Current Opinion in Neurobiology, 18: 541-543. 26. Isa T, Hall WC (2009) exploring the superior colliculus in vitro. Journal of Neurophysiology (review), 102: 2581-2593. 27. Isa T, Yoshida M. (2009) Saccade control after V1 lesion revisited. Current Opinion in Neurobiology, in press.

Publications

(Original papers)
1. Isa T, Kurosawa M, Sato A, Swenson RS (1985) Reflex responses evoked in the adrenal sympathetic nerve to electrical stimulation of somatic afferent nerves in the rat. Neuroscience Research 3:130-144.
2. Isa T, Itouji T, Sasaki S (1988) Excitatory pathways from Forel's field H to head elevator motoneurones in the cat. Neuroscience Letters 90 :89-94.
3. Isa T, Itouji T, Nakao S, Sasaki S (1988) Subtypes of neurones in Forel's field H as defined by their axonal projection. Neuroscience Letters 90:95-99.
4. Isa T, Sasaki S (1988) Effects of lesion of paramedian pontomedullary reticular formation by kainic acid injection on the visually triggered horizontal head movements in cat. Neuroscience Letters 87: 233-239.
5. Alstermark B, Isa T, Lundberg A, Pettersson L-G, Tantisira B (1989) The effect of low pyramidal lesions on forelimb movements in the cat. Neuroscience Research 7: 71-75.
6. Alstermark B, Isa T, Kummel H, Tantisira B (1990) Projection from excitatory C3-C4 propriospinal neurones to lamina VII and VIII neurones in the C6-Th1 segments of the cat. Neuroscience Research 8:131-137.
7. Alstermark B, Isa T, Tantisira B (1990) Projection from excitatory C3-C4 propriospinal neurones to spinocerebellar and spinoreticular neurones in the C6-Th1 segments of the cat. Neuroscience Research 8: 124-130.
8. Isa T, Pettersson L-G (1991) Effect of naloxone on transmission in excitatory and inhibitory spinal reflex pathways. Neuroscience Research 12:388-391.
9. Alstermark B, Isa T, Tantisira B (1991) Integration in descending motorpathways controlling the forelimb in the cat. 18. Morphology, axonal projection and termination of collaterals from C3-C4 propriospinal neurones in the segment of origin. Experimental Brain Research 88:561-568.
10. Alstermark B, Isa T, Tantisira B (1991) Pyramidal excitation in long propriospinal neurones in the cervical segments of the cat. Experimental Brain Research 84:569-582.
11. Isa T, Sasaki S (1992) Descending projections from Forel's field H neurones to the brain stem and the upper cervical spinal cord in the cat. Experimental Brain Research 88:563-579.
12. Isa T, Sasaki S (1992) Mono- and disynaptic pathways from Forel's field H to dorsal neck motoneurones in the cat. Experimental Brain Research 88:580- 593.
13. Isa T, Itouji T (1992) Axonal trajectories of single Forel's field H neurones in the mesencephalon, pons and medulla oblongata in the cat. Experimental Brain Research 89:484-495.
14. Alstermark B, Isa T, Lundberg A, Pettersson L-G, Tantisira B (1993) Characteristics of target reaching in cats. II. Reaching to targets at different locations. Experimental Brain Research 94:287-294.
15. Isa T, Naito K (1994) Activity of neurons in Forel's field H during orienting head movements in alert head-free cats. Experimental Brain Research 100:187-199.
16. Isa T, Naito K (1995) Activity of neurons in the medial pontomedullary reticular formation during orienting movements in alert head-free cats. Journal of Neurophysiology 74 : 73-95.
17. Isa T, Iino M, Itazawa S, Ozawa S (1995) Spermine mediates inward rectification of Ca2+- permeable AMPA receptor channels. Neuroreport 6:2045-2048.
18. Isa T, Itazawa S, Iino M, Tsuzuki K, Ozawa S (1996) Distribution of neurones expressing inwardly rectifying and Ca2+-permeable AMPA receptors in rat hippocampal slices. Journal of Physiology. (London) 491 : 719 - 733.
19. Iino M, Koike M, Isa T, Ozawa S (1996) Voltage dependent blockage of Ca2+- permeable AMPA receptors by Joro spider toxin in cultured rat hippocampal neurones. Journal of Physiology (London) 496: 431-437.
20. Tantisira B, Alstermark B, Isa T, Kummel H, Pinter M (1996) Motoneuronal projection pattern of single C3-C4 propriospinal neurones. Canadian Journal of Physiology & Pharmacology 74:518-530.
21. Isa T, Iino M, Ozawa S (1996) Spermine blocks synaptic transmission mediated by Ca2+- permeable AMPA receptors. Neuroreport 7: 689-692.
22. Itazawa S, Isa T, Ozawa S (1997) Inwardly rectifying and Ca2+- permeable AMPA-type glutamate receptor channels in rat neocortical neurons. Journal of Neurophysiology, 78:2592-2601.
23. Pettersson L-G, Lundberg A, Alstermark B, Isa T, Tantisira B (1997) Effect of spinal cord lesions on forelimb target-reaching and on visually guided switching of target-reaching in the cat. Neuroscience Research, 29:241-256.
24. Isa T, Endo T, Saito Y (1998) The visuo-motor pathway in the local circuit of the rat superior colliculus. Journal of Neuroscience 18: 8496-8504.
25. Aizawa H, Kobayashi Y, Yamamoto M, Isa T (1999) Injection of nicotine into the superior colliculus facilitates occurrence of express saccades in monkeys. Journal of Neurophysiology 82: 1642-1646.
26. Saito Y, Isa T (1999) Electrophysiological and morphological properties of neurons in the rat superior colliculus. I. Neurons in the intermediate layer. Journal of Neurophysiology 82: 754-767.
27. Sasaki S, Isa T, Naito K (1999) Effects of lesion of pontomedullary reticular formation on visually triggered vertical and oblique head orienting movements in alert cats. Neuroscience Letters. 265: 13-16.
28. Alstermark B, Isa T, Ohki Y, Saito Y. (1999) Disynaptic pyramidal excitation in forelimb motoneurons mediated via C3-C4 propriospinal neurons in the macaca fuscata. Journal of Neurophysiology, 82: 3580-3585.
29. Saito Y, Isa T (2000) Voltage-gated transient outward currents neurones with different firing properties in rat superior colliculus. Journal of Physiology (London), 528: 91-105.
30. Tsuzuki K, Isa T, Ozawa S (2000) Subunit composition of AMPA receptors expressed by single hippocampal neurons. Neuroreport 11:3583-3587.
31. Endo T, Isa T (2001) Functionally different AMPA-type glutamate receptors in morphologically identified neurons in superficial layer of rat superior colliculus. Neuroscience, 108: 129-141.
32. Kobayashi Y, Inoue Y, Yamamoto M, Isa T, Aizawa H (2002) Contribution of pedunculopontine tegmental nucleus neurons to performance of visually guided saccade tasks in monkeys. Journal of Neurophysiology, 88:715-731.
33. EndoT, Isa T (2002) Postsynaptic and presynaptic GABAB receptor-mediated inhibition in rat superficial superior colliculus neurons. Neuroscience Letters 322: 126-130.
34. Saito Y, Isa T (2003) Local excitatory network and NMDA receptor activation generate a synchronous and non-linear bursting command from the superior colliculus. Journal of Neuroscience, 23:5854-5864.
35. Katsuta H, Isa T (2003) Release from GABAA receptor-mediated inhibition unmasks interlaminar connection within superior colliculus in anesthetized adult rats. Neuroscience Research, 46:73-83.
36. Yamashita T, Isa T (2003) Fulfenamic acid sensitive, Ca2+-dependent inward current induced by nicotinic acetylcholine receptors in dopamine neurons. Neuroscience Research, 46:463-473.
37. Endo T, Yanagawa Y, Obata K, Isa T (2003) Characteristics of GABAergic neurons in the superficial superior colliculus. Neuroscience Letters, 346:81-84.
38. Yamashita T, Isa T (2003) Ca2+-dependent inward current induced by nicotinic receptor activation depends on Ca2+/calmodulin-CaMKII pathway in dopamine neurons. Neuroscience Research, 47: 225-232.

39. Saitoh K, Hattori S, Song W-J, Isa T, Takakusaki K (2003) Nigral GABAergic inhibition upon cholinergic neurons in the rat pedunculopontine tegmental nucleus. European Journal of Neuroscience, 18: 879-886.

40. Alstermark B, Ogawa J, Isa T (2004) Lack of monosynaptic corticomotoneuronal excitation in the adult rat: fast disynaptic excitation is mediated via reticulospinal neurones and slow polysynaptic excitation via segmental interneurons. Journal of Neurophysiology, 91:1832-1839.

41. Yamashita T, Isa T (2004) Enhancement of excitatory postsynaptic potentials by preceding application of acetylcholine in mesencephalic dopamine neurons. Neuroscience Research 49: 91-100.

42. Sakatani T, Isa T (2004) PC-based high-speed video-oculography for measuring rapid eye movements in mice. Neuroscience Research, 49:123-131.

43. Tanaka H, Ono K, Shibasaki H, Isa T, Ikenaka K (2004) Conduction properties of identified neural pathways in the central nervous system of mice in vivo. Neuroscience Research, 49:113-122.

44. Saitoh K, Isa T, Takakusaki K (2004) Nigral GABAergic inhibition upon mesencephalic dopaminergic cell groups in rats. European Journal of Neuroscience, 19:2399-2409.

45. Saito Y, Isa T (2004) Laminar specific distribution of lateral excitatory connections in the rat superior colliculus. Journal of Neuophysiology, in press.

46. Sasaki S, Isa T, Pettersson L-G, Alstermark B, Naito K, Yoshimura K, Seki K, Ohki Y (2004) Dexterous finger movements in primate without monosynaptic corticomotoneuronal excitation. Journal of Neurophysiology, 92:3142-3147.

47.Li F, Endo T, Isa T (2004) Presynaptic muscarinic acetylcholine receptors suppress GABAergic synaptic transmission in the intermediate gray layer of mouse superior colliculus. European Journal of Neuroscience, 20:2079-2088.

48. Sasaki S, Naito K, Yoshimura K, Isa T, Seki K, Pettersson LG, Alstermark B & Ohki Y (2004) Cortico-motoneuronal system and dexterous finger movements. Journal of Neurophysiology 92:3601-3603.

49. Watanabe M, Kobayashi Y, Inoue Y, Isa T (2005) Effects of local nicotinic activation of the superior colliculus on saccades in monkeys. Journal of Neurophysiology, 93: 519-534.

50. Saito Y, Isa T (2005) Organization of interlaminar interactions in the rat superior colliculus. Journal of Neurophysiology, 93:2898-2907.

51. Sooksawate T, Saito Y, Isa T (2005) Electrophysiological and morphological properties of identified crossed tecto-reticular neurons in the rat superior colliculus. Neuroscience Research, 52:174-184.

52. Endo T, Yanagawa Y, Obata K, Isa T (2005) Nicotinic acetylcholine receptor subtypes involved in facilitation of GABAergic inhibition in mouse superficial superior colliculus. Journal of Neurophysiology, 94: 3893-3902.

54. Isa T, Ohki Y, Seki K, Alstermark B (2006) Properties of propriospinal neurons in the C3-C4 segments mediating disynaptic pyramidal excitation to forelimb motoneurons in the macaque monkey. Journal of Neurophysiology, 95: 3674-3685.

55. Tanaka H, Ikenaka K, Isa T (2006) Electrophysiological abnormalities precede apparent histological demyelination in the central nervous system of mice overexpressing proteolipid protein. Journal of Neuroscience Research 84: 1206-1216.

56. Sooksawate T, Isa T (2006) Properties of cholinergic responses in neurons in the intermediate gray layer of rat superior colliculus. European Journal of Neuroscience, 24: 3096-3108.

57. Lee PH*, Sooksawate T*, Yanagawa Y, Isa K, Isa T**, Hall WC** (2007) Identity of a pathway for saccadic suppression. Proceedings of National Academy of Sciences, USA 104: 6824-6827. * = equal contribution, **= co-corresponding authors

58. Sakatani T, Isa T (2007) Quantitative analysis of saccade-like rapid eye movements in C57BL/6 mice. Neuroscience Research 58: 324-331.

59. Nishimura Y, Onoe T, Morichika Y, Tsukada H, Isa T (2007) Activation of parieto-frontal stream during reaching and grasping studied by positron emission tomography in monkeys. Neuroscience Research, 59: 243-250.

60. Sato A, Nishimura Y, Oishi T, Higo N, Murata Y, Onoe H, Saito K, Tsuboi F, Takahashi M, Isa T, Kojima T (2007) Differentially expressed genes among motor and prefrontal areas of macaque neocortex. Biochemical and Biophysical Research Communications, 362: 665-669.

61. Nishimura Y, Onoe T, Morichika Y, Perfiliev S, Tsukada H, Isa T (2007) Time-dependent central compensatory mechanism of finger dexterity after spinal-cord injury. Science, 318: 1150-1155.

62. Kaneda K, Phongphanphanee P, Katoh T, Isa K, Yanagawa Y, Obata K, Isa T (2008) Regulation of burst activity through pre- and postsynaptic GABAB receptors in mouse superior colliculus. Journal of Neuroscience, 28:816-827.

63. Endo T, Tarusawa E, Notomi T, Kaneda K, Hirabayashi M, Shigemoto R, Isa T (2008) Dendritic Ih ensures high-fidelity spike responses of motion sensitive neurons in rat superior colliculus. Journal of Neurophysiology, 99: 2066-2076.

64. Phongphanphanee P, Kaneda K, Isa T (2008) Spatio-temporal profiles of field potentials in mouse superior colliculus analyzed by multichannel recording. Journal of Neuroscience, 28: 9309-9318.

65. Sooksawate T, Isa K, Isa T (2008) Cholinergic responses in crossed tecto-reticular neurons of rat superior colliculus. Journal of Neurophysiology, 100: 2702-2711.

66. Yoshida M, Takaura K, Kato R, Ikeda T, Isa T (2008) Striate cortical lesions affect deliberate decision and control of saccade: implication for blindsight. Journal of Neuroscience, 28: 10517-10530.

67. Kaneda K, Isa K, Yanagawa Y, Isa T (2008) Nigral inhibition of GABAergic neurons in mouse superior colliculus. Journal of Neuroscience, 28: 11071-11078.

68. Nishimura Y, Morichika Y, Isa T (2009) A common subcortical oscillatory network contributes to recovery after spinal cord injury. Brain,132: 709-721.

69. Okada K, Toyama K, Inoue Y, Isa T, Kobayashi Y (2009) Different pedunculopontine tegmental neurons signal predicted and actual task rewards. Journal of Neuroscience, 29: 4858-4870.

70. Tanaka H, Tanaka K, Ma J, Isa T, Tanda K, Miyakawa T, Suzuki A, Ishibashi T, Baba H, Shigemoto R, Ono K, Ikenaka K (2009) Mice with altered myelin proteolipid protein gene expression show schizophrenia-related behavior accompanied by abnormal neuron-glial interaction and conduction velocity. Journal of Neuroscience, 29: 8363-8371.

71. Higo N, Nishimura Y, Murata Y, Oishi T, Saito K, Takahashi M, Tsuboi F, Isa T (2009) Increased expression of the growth-associated protein-43 gene in the sensorimotor cortex of the macaque monkey after lesioning of the lateral corticospinal tract. Journal of Comparative Neurology, 516: 493-506.

72. Takahashi M, Vattanajun A, Umeda T, Isa K, Isa T (2009) Large-scale reorganization of corticofugal fibers after neonatal hemidecortication for functional restoration of forelimb movements. European Journal of Neuroscience, in press.

(Review Articles)
1. Isa T, Itouji T, Sasaki S (1992) Control of head movement in the cat: two separate pathways from the superior colliculus to neck motoneurones and their roles in orienting movements. In: "Vestibular and brain stem control of eye, head and body movements." (eds) Shimazu H & Shinoda Y, Jpn. Scientific Society Press, pp275-284.
2. Isa T, Itouji T, Sasaki S (1992) Control of vertical head movement via Forel's field H. In : "The Head-Neck Sensory Motor System" (eds) Berthoz A, Graf W& Vidal PP, Oxford Univ. Press, Chapter 52, pp345-350.
3. Isa T, Itouji T, Naito K, Sasaki S (1993) Control of head movements during orienting and visual discrimination. Biomedical Research 14, Suppl 1, 47-49.
4. Ozawa S, Isa T, Tsuzuki K, Iino M (1996) Ca2+ permeability and subunit composition of AMPA receptors in hippocampal neurons. In : "Integrative and Molecular Approach to Brain Function." (eds) Ito M, Miyashita Y, Elsevier, Amsterdam, pp47-56.
5. Isa T, Sasaki S (1999) Neural mechanisms for the control of visually guided orienting movements of the head. In : “Motor Control Today and Tomorrow (ed. G.N. Gantchev, S. Mori, J. Massion, Academic Publishing House “Prof. M. Drinov, Sofia)”, pp57 - 69.
6. Isa T (1999) A role of brainstem acetylcholinergic system in regulating initiation of saccadic eye movements. In : “From Basic Motor Control to Functional Recovery” (eds. N. Gantchev & G.N. Gantchev), pp19－23.
7. Kobayashi Y, Saito Y, Isa T (2001) Facilitation of saccade initiation by brainstem cholinergic system. Brain Development, 23 S24-S27.
8. Isa T, Saito Y (2001) The direct visuo-motor pathway in mammalian superior colliculus; novel perspective on the interlaminar connection. Neuroscience Research, (update article) 41: 107-113.
9. Isa T, Sasaki S (2002) Brainstem control of head movements during orientation; organization of the premotor circuits. Progress in Neurobiology, 66: 205-241.
10. Alstermark B, Isa T (2002) Premotoneuronal and direct corticomotoneuronal control in the cat and macaque monkey. In “Movement and Sensation” (eds. Gandevia S, Proske U), Adv Exp Med Biol. 2002;508:281-297.
11. Kobayashi Y, Isa T (2002) Sensory-motor gating and cognitive control by the brainstem cholinergic system. Neural Networks 15:731-741.
12. Isa T (2002) Intrinsic processing in the mammalian superior colliculus. Current Opinion in Neurobiology, 12:668-677.
13. Isa T, Kobayashi Y, Saito Y (2003) Dynamic modulation of signal transmission in the local circuit of mammalian superior colliculus. In “The Superior Colliculus: New Approaches for Studying Sensorimotor Integration.” (eds. W.C. Hall & A. K. Moschovakis), CRC Press, pp159-171.
14. Isa T & Kobayashi Y (2003) Switching between cortical and subcortical sensorimotor pathways. In Progress in Brain Research “Brain Mechanisms for the integration of posture and movement”. (eds. Mori S, Stuart DG, Wiesendanger M) 143:295-301.
15.Kobayashi Y, Inoue Y & Isa T (2003) Pedunculo-pontine control of visually guided saccades. In Progress in Brain Research “Brain Mechanisms for the integration of posture and movement”. (eds. Mori S, Stuart DG, Wiesendanger M) 143:439-445.
16. Isa T, Inoue Y, Kobayashi Y (2003) Cognitive function of the brainstem cholinergic system. In International Congress Series 1250 “Cognition and Emotion in the Brain” (eds. Ono t, Matsumoto G, Llinas R, Berthoz A, Norgren R, Nishijo H, Tamura R), pp397-406.
17. Isa T & Sparks D (2005) Microcircuit of the Superior Colliculus: A Neuronal Machine that Determines Timing and Endpoint of Saccadic Eye Movements. Background paper for 93rd Dahlem Workshop on Microcircuits; The interface between Neurons and Global Brain Function.

18. Kiehn, O., Buschges, A., Duch, C., Grillner, S., Isa, T., Lansner, A., Pfluger, H.-J., Richter, D.W., Sillar, K.T., smith, J.C., Sparks, D.L. (2006) Group report: Microcircuits in the motor system. “Microcircuits. The interface between neurons and global brain function.” (eds. S. Grillner & A.M. Graybiel), pp77-104, The MIT Press.

19. Alstermark, B. Isa, T., Pettersson, L-G., Sasaki, S (2007) The C3-C4 propriospinal system in the cat and monkey; a spinal premotoneuronal centre for voluntary motor control. Acta.Physiol. Scand., 189: 123-140.

20. Pettersson L.-G.., Alstermark, B., Blagovechtchenski, E., Isa, T., Sasaski, S(2007) Skilled digit movements in feline and primate ? descending control and motor recovery after spinal cord injuries. Acta Physiol. Scand., 189: 141-154.

21. Isa, T., Ohki, Y., Alstermark, B., Pettersson, L-G., Sasaki, S (2007) Direct and indirect cortico-motoneuronal pathways and control of hand/arm movements. Physiology, 22: 145-152.

22. Sakatani T, Isa T (2008) Superior colliculus and saccade generation in mice. In “Eyes, Retina and Visual System of the Mouse” (eds Calupa Leo.M. & Willliams R), MIT Press, pp233-244.

23. Isa T, Schwartz AB. (2008) Introduction. Current Opinion in Neurobiology, 18: 541-543.

24. Nishimura Y, Isa T (2009) Compensatory changes at the cerebral cortical level after spinal cord injury. The Neuroscientist, 15: 436-444.

25. Isa T, Schwartz AB. (2008) Introduction. Current Opinion in Neurobiology, 18: 541-543.

26. Isa T, Hall WC (2009) exploring the superior colliculus in vitro. Journal of Neurophysiology (review), 102: 2581-2593.

27. Isa T, Yoshida M. (2009) Saccade control after V1 lesion revisited. Current Opinion in Neurobiology, in press.

	Prof. Tadashi Isa
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