2015年 2014年 2013年 2012年 2011年
2010年 2009年 2008年 2007年 2006年
2005年 2004年 2003年 2002年 2001年
2000年 1999年 1998年 1997年 1996年    

■ 2016年

Ishida A, Isa K, Umeda T, Kobayashi K, Kobayashi K, Hida H, Isa T (2016) Causal link between the cortico-rubral pathway and functional recovery through forced impaired limb use in rats with stroke. J Neurosci, 36:455-467.


■ 2015年

Sawada M, Kato K, Kunieda T, Mikuni N, Miyamoto S, Onoe H, Isa T, Nishimura Y (2015) Function of nucleus accumbens in motor control during recovery after spinal cord injury. Science, 350: 98-101.

Sadakane O, Watakabe A, Ohtsuka M, Takaji M, Sasaki T, Kasai M, Isa T, Kato G, Nabekura J, Mizukami H, Ozawa K, Kawasaki H, Yamamori T (2015) In vivo two-photon imaging of dendritic spines in marmoset neocortex. eNeuro. 2(4). pii: ENEURO.0019-15.2015.

Yoshida M, Isa T (2015) Signal detection analysis of blindsight in monkeys. Sci Rep, 5:10755.

Kato K, Sasada S, Nishimura Y (2015) Flexible adaptation to an artificial recurrent connection from muscle to peripheral nerve in man. J Neurophysiol. in press. doi: 10.1152/jn.00143.2015.

Murata Y, Higo N, Hayashi T, Nishimura Y, Sugiyama Y, Oishi T, Tsukada H, Isa T, Onoe H. (2015) Temporal plasticity involved in recovery from manual dexterity deficit after motor cortex lesion in macaque monkeys. J Neurosci, 35: 84-95.

Kondo T, Yoshihara Y, Saito-Yoshino K, Sekiguchi T, Kosugi A, Miyazaki Y, Nishimura Y, Okano HJ, Nakamura M. Okano H, Isa T, Ushiba J (2015) Histological and electrophysiological analysis of the corticospinal pathway to forelimb motoneurons in common marmosets. Neurosci Res, 98: 35-44.

Murata Y, Higo N, Oishi T, Isa T (2015) Increased expression of the growth-associated protein-43 gene after primary motor cortex lesion in macaque monkeys. Neurosci Res, 98: 64-69.

Watakabe A, Ohtsuka M, Kinoshita M, Takaji M, Isa K, Mizukami H, Ozawa K, Isa T, Yamamori T (2015) Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex. Neuroscience Research 93:144-157.

Carelli FN, Hayakawa T, Go Y, Imai H, Warnefors M, Kaessmann H (2016) The life history of retrocopies illuminates the evolution of new mammalian genes. Genome Research, in press.

Suzuki-Hashido N, Hayakawa T, Matsui A, Go Y, Ishimaru Y, Misaka T, Abe K, Hirai H, Satta Y, Imai H. (2015) Rapid expansion of phenylthiocarbamide non-tasters among Japanese macaques. PLOS ONE 10:e0132016.

Tadashi Isa (2015) Large-scaled network reorganization during recovery from partial spinal cord injury. In “Clinical Systems Neuroscience” (eds. Kansaku K, Cohen LG, Birbaumer N), Springer, pp121-138.


■ 2014年

Umeda T, Isa T and Nishimura Y(2014). Proprioceptive information coded by populational sensory afferents. J Phys Fitness Sports Med, 2014 3(5):477-482. DOI:10.7600/jpfsm.3.477.2014/7/6

Chuong A, Miri M, Busskamp V, Matthews G, Acker L, Sorensen A, Young A, Klapoetke N, Henninger M, Kodandaramaiah S, Ogawa M, Ramanlal S, Bandler R, Allen B, Forest C, Chow B, Han X, Lin Y, Tye K, Roska B, Cardin J, Boyden E (2014) Noninvasive optical inhibition with a red-shifted microbial rhodopsin. Nature Neuroscience, Vol 17, 2014, P1123-1129.

Morishita S, Sato K, Watanabe H, Nishimura Y, Isa T, Kato R, Nakamura T, Yokoi H. (2014) Brain-machine interface to control a prosthetic arm with monkey ECoGs during periodic movements. Front. Neurosci.,2014 Dec 12;8:417. doi: 10.3389/fnins.2014.00417. eCollection 2014.

Watanabe H, Tsubokawa H, Tsukada M, Aihara T. (2014) Frequency-dependent signal processing in apical dendrites of hippocampal CA1 pyramidal cells. Neuroscience, 278:194-210. doi: 10.1016/j.neuroscience.2014.07.069.

Sasada S, Kato K, Kadowaki S, Groiss SJ, Ugawa Y, Komiyama T, Nishimura Y(2014)Volitional walking via upper limb muscle-controlled stimulation of the lumbar locomotor center in man. Journal of Neuroscience, 34:11131-11142.

Phongphanphanee P, Marino R, Kaneda K, Yanagawa Y, Munoz DP, Isa, T (2014) Distinct local circuit properties of the superficial and intermediate layers of the rodent superior colliculus. European Journal of Neuroscience, 40:2329-2343.

Umeda T, Watanabe H, Sato MA, Kawato M, Isa T, Nishimura Y (2014)Decoding of the spike timing of primary afferents during voluntary arm movements in monkeys. Frontiers in Neuroscience, 8:97.

Watanabe H, Sakatani T, Suzuki T, Sato MA, Nishimura Y, Nambu A, Kawato M, Isa T (2014) Reconstruction of intracortical whisker-evoked local field potential from electrocorticogram using a model trained for spontaneous activity in the rat barrel cortex.  Neuroscience Research pii: S0168-0102(14)00121-7. doi: 10.1016/j.neures.2014.06.010.

Chen C, Shin D, Watanabe H, Nakanishi Y, Kambara H, Yoshimura N, Nambu A, Isa T, Nishimura Y, Koike Y (2014) Decoding grasp force profile from electrocorticography signals in non-human primate sensorimotor cortex. Neuroscience Research, pii: S0168-0102(14)00047-9. doi: 10.1016/j.neures.2014.03.010..

Wanakhachornkrai O, Umeda T, Isa K, Tantisira M, Tantisira B, Isa T (2014) Reorganization of sensory pathways after neonatal hemidecortication in rats. Neuroscience Research 79: 94-98.

Yoshida M, Veale R (2014) Saliency-guided neural prosthesis for visual attention: Design and simulation. Neuroscience Research, 78: 90-94.

Hutchinson M, Isa T, Molloy A, Kimmich O, Williams L, Molloy F, Moore H, Healy DG, Lynch T, Walsh C, Butler J, Reilly RB, Walsh R, O'Riordan S(2014)Cervical dystonia: a disorder of the midbrain network for covert attentional orienting. Front Neurol. 5:54

Isa T, Nishimura Y (2014) Plasticity after partial spinal cord injury-Hierarchical organization- Neuroscience Research 78: 3-8 (review).

Umeda T, Funakoshi K (2014) Reorganization of motor circuits after neonatal hemidecortication. Neuroscience Research, 78: 30-37 (review).

Watanabe H, Takahashi K, Nishimura Y, Isa T (2014) Phase and magnitude spatiotemporal dynamics of β oscillation in electrocorticography (ECoG) in the monkey motor cortex at the onset of 3D reaching movements. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug; 2014:5196-9.

■ 2013年

Nishimura Y, Perlmutter SI, Eaton RW, Fetz EE (2013) Spike-timing dependent plasticity in primate corticospinal connections induced during free behavior. Neuron 80: 1301-1309.

Chen D, Shin D, Watanabe H, Nakanishi Y, Kambara H, Yoshimura N, Nambu A, Isa T, Nishimura Y, Koike Y (2013) Prediction of hand trajectory from electrocorticography signals in primary motor cortex. PLos One, 8: e83534.

Sooksawate T, Isa K, Matsui R, Kato S, Kinoshita M, Kobayashi K, Watanabe D, Kobayashi K, Isa T (2013) Viral vector-mediated selective and reversible blockade of the pathway for visual orienting in mice. Frontiers in Neural Circuits. 7:162.

Yamamoto T, Oishi T, Higo N, Murayama S, Sato A, Takashima I, Sugiyama Y, Nishimura Y, Murata Y, Yoshino-Saito K, Isa T, Kojima T (2013) Expression of secreted phosphoprotein 1 in the motor cortex among primate species and during postnatal development and functional recovery. PLos One, 8:e65701.

Takei T, Seki S (2013) Spinal premotor interneurons mediate dynamic and static motor commands for precision grip in monkeys. Journal of Neuroscience, 33:8850-8860.

Takei T, Seki K (2013) Synaptic and functional linkages between spinal premotor interneurons and hand-muscle activity during precision grip. Frontiers in Computational Neuroscience 7:40.

Nishimura Y, Perlmutter SI, Fetz EE (2013) Restoration of upper limb movement via artificial corticospinal and musculospinal connetions in a monkey with spinal cord injury. Frontiers in Neural Circuits 7:57.

Sugiyama Y, Higo N, Yoshino-Saito K, Murata Y, Nishimura Y, Oishi T, Isa T (2013) Effects of early versus late rehabilitative training on manual dexterity after corticospinal tract lesion in macaque monkeys. Journal of Neurophysiology, 109: 2853-2865.

Kaneda K, Isa T (2013) GABAergic mechanisms for shaping transient visual responses in the mouse superior colliculus. Neuroscience, 235: 129-140.

Kojima T, Higo N, Oishi T, Nishimura Y, Yamamoto T, Murata Y, Yoshino-Saito K, Onoe H, Isa T (2013) Gene network analysis of differentially expressed genes between primary motor and prefrontal association cortices of macaque brain. Neurochemical Research 38: 133-140.

Isa T, Kinoshita M, Nishimura Y (2013) Role of direct vs indirect pathways from the motor cortex to spinal motoneurons in the control of hand dexterity. Frontiers in Neurology, 4:191 (review).

■ 2012年

Umeda T, Seki K, Sato M, Nishimura Y, Kawato M, Isa T (2012) Population coding of forelimb joint kinematics by peripheral afferents in monkeys. PLoS ONE 7: e47749.

Shin D, Watanabe H, Kambara H, Nambu A, Isa T, Nishimura Y, Koike Y (2012) Prediction of Muscle Activities from Electrocorticograms in Primary Motor Cortex of Primate. PLoS ONE 7: e47992.

Yoshida M, Itti L, Berg D, Ikeda T, Kato R, Takaura K, White BJ, Munoz DP, Isa T (2012) Residual Attention Guidance in Blindsight Monkeys Watching Complex Natural Scenes. Current Biology 22: 1429-1434.

Kinoshita M, Matsui R, Kato S, Hasegawa T, Kasahara H, Isa K, Watakabe A, Yamamori T, Nishimura Y, Alstermark B., Watanabe D, Kobayashi K, Isa T (2012) Genetic dissection of the circuit for hand dexterity in primates. Nature 487: 235-238.

Watanabe H, Sato M, Suzuki T, Nambu A, Nishimura Y, Kawato M, Isa T (2012) Reconstruction of movement-related intracortical activity from micro-electrocorticogram array signals in monkey primary motor cortex. Journal of Neural Engineering, 9:036006

Sooksawate T, Yanagawa Y, Isa T (2012) Cholinergic responses in GABAergic neurons in the intermediate gray layer of mouse superior colliculus. European Journal of Neuroscience 36: 2440-2451.

Kaneda K, Yanagawa Y, Isa T (2012) Transient enhancement of inhibition following visual cortical lesions in the mouse superior colliculus. European Journal of Neuroscience 36: 3066-3076.

Seki K, Fetz EE (2012) Gating of sensory input at spinal and cortical levels during preparation and execution of voluntary movement. Journal of Neuroscience 32: 890-902.

Alstermark B, Isa T (2012) Circuits for skilled reaching and grasping. Annual Review of Neuroscience 35:559-578.

Nishimura Y, Isa T (2012) Cortical and subcortical compensatory mechanisms after spinal cord injury in monkeys. Experimental Neurology, Special Issue “Plasticity after spinal cord injury” invited review, 235:152-161.

■ 2011年

Nishimura Y, Onoe H, Onoe K, Morochika Y, Tsukada H, Isa T (2011) Neural substrate for the motivational regulation of motor recovery after spinal-cord injury. PLos One, 6:e24854.

Umeda T, Isa T (2011) Differential contributions of rostral and caudal frontal forelimb areas to compensatory process after neonatal hemidecortication in rats. European Journal of Neuroscience, 34: 1453-1460.

Alstermark B, Pettersson L-G, Nishimura Y, Yoshino-Saito K, Tsuboi F, Takahashi M, Isa T (2011) Motor command for precision grip in the Macaque Monkey can be mediated by spinal interneurons. Journal of Neurophysiology, 106: 122-126.

Kaneda K, Kasahara H, Matsui M, Katoh T, Mizukami H, Ozawa K, Watanabe D, Isa T (2011) Selective optical control of synaptic transmission in the subcortical visual pathway by activation of viral vector-expressed halorhodopsin. PLos One, 6: e18452.

Takaura K, Yoshida M, Isa T (2011) Neural substrate of spatial memory in the superior colliculus after damage to the primary visual cortex. Journal of Neuroscience, 31: 4233-4241

Phongphanphanee P, Mizuno F, Lee PH, Yanagawa Y, Isa T, Hall WC (2011) A circuit model for saccadic suppression in the superior colliculus. Journal of Neuroscience, 31: 1949-1954

Sooksawate T, Isa K, Behan M, Yanagawa Y, Isa T. (2011) Organization of GABAergic inhibition in the motor output layer of the superior colliculus. European Journal of Neuroscience, 33: 321-432.

Yamamoto T, Higo N, Sato A, Nishimura Y, Oishi T, Murata Y, Yoshino-Saito K, Isa T, Kojima T (2011) SPP1 expression in voluntary spinal motor neurons of the macaque monkey. Neuroscience Research, 69:81-86

Kato R, Takaura K, Ikeda T, Yoshida M, Isa T (2011) Contribution of the retino-tectal pathway to visually guided saccades after lesion of the primary visual cortex in monkeys. European Journal of Neuroscience, 33: 1952-1960.


■ 2010年

Higo N, Sato A, Yamamoto T, Nishimura Y, Oishi T, Murata Y, Onoe H, Yoshino-Saito K, Tsuboi F, Takahashi M, Isa T, Kojima T (2010) SPP1 is selectively expressed in corticospinal neurons of the macaque sensorimotor cortex. Journal of Comparative Neurology 518: 2633-2644.

Ikeda T, Yoshida M, Isa T. (2010) Lesion of Primary Visual Cortex in Monkey Impairs the Inhibitory but Not the Facilitatory Cueing Effect on Saccade. Journal of Cognitive Neuroscience, Early Access, Online June 3 (doi:10.1162/jocn.2010.21529).

Umeda T, Takahashi M, Isa K, Isa T. (2010) Formation of descending pathways mediating cortical command to ipsilateral forelimb motoneurons in neonatally hemidecorticated rats. Journal of Neurophysiology 104: 1707-1716.

Tsuboi F, Nishimura Y, Yoshino-Saito K, Isa T (2010) Neuronal mechanism of mirror movements caused by dysfunction of the motor cortex. European Journal of Neuroscience 32: 1397-1406.

Perfiliev S, Isa T, Johnels B, Steg G, Wessberg J (2010) Reflexive limb selection and control of reach direction to moving targets in cats, monkeys and humans. Journal of Neurophysiology 104: 2423-2432.

Yoshino-Saito K, Nishimura Y, Oishi T, Isa T (2010) Quantitative inter-segmental and inter-laminar comparison of corticospinal projection from the forelimb area of primary motor cortex of macaque monkeys. Neuroscience 171: 1164-1179.

Takei T, Seki K (2010) Spinal interneurons facilitate coactivation of hand muscles during a precision grip task in monkeys. Journal of Neuroscience 30: 17041-17050.

Kaneda K, Isa T. (2010) Superior Colliculus. “Handbook of Brain Microcircuits” (eds. Shepherd GM, Grillner S), Oxford Univ Press, pp311-316.


■ 2009年

Takahashi M, Vattanajun A, Umeda T, Isa K, Isa T (2009) Large-scale reorganization of corticofugal fibers after neonatal hemidecortication for functional restoration of forelimb movements. European Journal of Neuroscience, 30: 1878-1887.

Nishimura Y, Morichika Y, Isa T (2009) A common subcortical oscillatory network contributes to recovery after spinal cord injury. Brain, 132: 709-721.

Okada K-I, Toyama K, Inoue Y, Isa T, Kobayashi Y (2009) Different pedunculopontine tegmental neurons signal predicted and actual task rewards. Journal of Neuroscience, 29: 4858-4870.

Tanaka H, Ma J, Tanaka KF, Takao K, Komada M, Tanda K, Suzuki A, Ishibashi T, Baba H, Isa T, Shigemoto R, Ono K, Miyakawa T, and Ikenaka K (2009) Mice with altered myelin proteolipid protein gene expression show schizophrenia-related behavior accompanied by abnormal neuron-glial interaction and conduction velocity. Journal of Neuroscience, 29: 8363-8371.

Higo N, Nishimura Y, Murata Y, Oishi T, Saito K, Takahashi M, Tsuboi F, Isa T (2009) Increased expression of the growth-associated protein-43 gene in the sensorimotor cortex of the macaque monkey after lesioning of the lateral corticospinal tract. Journal of Comparative Neurology, 516: 493-506.

Seki K, Perlmutter SI, Fetz EE (2009) Task-dependent modulation of primary afferent depolarization in cervical spinal cord of monkeys performing an instructed delay task. Journal of Neurophysiology,102: 85-99.

Nishimura Y, Isa T (2009) Compensatory changes at the cerebral cortical level after spinal cord injury. The Neuroscientist (review), 15: 436-444.

Isa T, Hall WC (2009) Exploring the superior colliculus in vitro. Journal of Neurophysiology (review), 102: 2581-2593.

Isa T, Yoshida M. (2009) Saccade control after V1 lesion revisited. Current Opinion in Neurobiology (review), 19: 608-614.


■ 2008年

Takei T, Seki K (2008) Spinomuscular coherence in monkeys performing a precision grip task. Journal of Neurophysiology, 99:2012-2020.

Kaneda K, Phongphanphanee P, Katoh T, Isa K, Yanagawa Y, Obata K, Isa T (2008) Regulation of burst activity through pre- and postsynaptic GABAB receptors in mouse superior colliculus. Journal of Neuroscience, 28:816-827.

Endo T, Tarusawa E, Notomi T, Kaneda K, Hirabayashi M, Shigemoto R, Isa T (2008) Dendritic Ih ensures high-fidelity spike responses of motion sensitive neurons in rat superior colliculus. Journal of Neurophysiology, 99: 2066-2076.

Phongphanphanee P, Kaneda K, Isa T (2008) Spatio-temporal profiles of field potentials in mouse superior colliculus analyzed by multichannel recording. Journal of Neuroscience, 28: 9309-9318.

Sooksawate T, Isa K, Isa T (2008) Cholinergic responses in crossed tecto-reticular neurons of rat superior colliculus. Journal of Neurophysiology, 100: 2702-2711.

Yoshida M, Takaura K, Kato R, Ikeda T, Isa T (2008) Striate cortical lesions affect deliberate decision and control of saccade: implication for blindsight. Journal of Neuroscience, 28: 10541-10548.

Kaneda K, Isa K, Yanagawa Y, Isa T (2008) Nigral inhibition of GABAergic neurons in mouse superior colliculus. Journal of Neuroscience, 28: 11071-11078.

Sakatani T, Isa T (2008) Superior colliculus and saccade generation in mice. In “Eyes, Retina and Visual System of the Mouse” (eds Calupa Leo.M. & Willliams R), MIT Press, pp233-244.

Isa T, Schwartz AB. (2008) Motor systems. Introduction. Current Opinion in Neurobiology 18: 541-543.


■ 2007年

Psyche H. Lee, Thongchai Sooksawate, Yuchio Yanagawa, Kaoru Isa, Tadashi Isa and William C. Hall (2007) Identity of a pathway for saccadic suppression. PNAS Vol.104 no.16:6824-6827.

Sakatani T, Isa T (2007) Quantitative analysis of saccade-like rapid eye movements in C57BL/6 mice. Neuroscience Research, 58: 324-331.

Nishimura Y, Onoe T, Morichika Y, Tsukada H, Isa T (2007) Activation of parieto-frontal stream during reaching and grasping studied by positron emission tomography in monkeys. Neuroscience Research 59: 243-250.

Sato A, Nishimura Y, Oishi T, Higo N, Murata Y, Onoe H, Saito K, Tsuboi F, Takahashi M, Isa T, Kojima T (2007) Differentially expressed genes among motor and prefrontal areas of macaque neocortex. Biochemical and Biophysical Research Communications, 362: 665-669.

Nishimura Y, Onoe H, Morichika Y, Perfiliev S, Tsukada H, Isa T (2007) Time-dependent central compensatory mechanisms of finger dexterity after spinal cord injury. Science. 318:1150-1155.

Alstermark, B. Isa, T., Pettersson, L-G., Sasaki, S (2007) The C3-C4 propriospinal system in the cat and monkey; a spinal premotoneuronal centre for voluntary motor control. Acta.Physiol. (Oxf), 189: 123-140.

Pettersson L.-G.., Alstermark, B., Blagovechtchenski, E., Isa, T., Sasaski, S (2007) Skilled digit movements in feline and primate ? descending control and motor recovery after spinal cord injuries. Acta Physiol. (Oxf), 189: 141-154.

Isa, T., Ohki, Y., Alstermark, B., Pettersson, L-G., Sasaki, S (2007) Direct and indirect cortico-motoneuronal pathways and control of hand/arm movements. Physiology, 22: 145-152.


■ 2006年

Sooksawate T, Isa T. (2006) Properties of cholinergic responses in neurons in the intermediate gray layer of rat superior colliculus. European Journal of Neuroscience, 24: 3096-3108.

Isa T, Ohki Y, Seki K, Alstermark B. (2006) Properties of propriospinal neurones in the C3-C4 segments mediating disynaptic pyramidal excitation to forelimb motoneurones in the macaque monkey. Journal of Neurophysilogy, 95: 3674-3685.

Tanaka H, Ikenaka K, Isa T. (2006) Electrophysiological abnormality precedes apparent histological demyelination in the CNS of mice over-expressing proteolipid protein. Journal Neuroscience Research, 84: 1206-1216.

Isa T & Sparks D (2006) Microcircuit of the Superior Colliculus: A Neuronal Machine that Determines Timing and Endpoint of Saccadic Eye Movements. Background paper for 93rd Dahlem Workshop on Microcircuits; The interface between Neurons and Global Brain Function, The MIT Press, Editors: S. Grillner and A.M. Graybiel, pp. 5-34.


■ 2005年

Endo T, Yanagawa Y. Obata K, Isa T. Nicotinic acetylcholine receptor subtypes involved in facilitation of GABAergic inhibition in mouse superficial superior colliculus. Journal of Neurophysiology, 94:3893-3902.

Watanabe M, Kobayashi Y, Inoue Y, Isa T (2005) Effects of local nicotinic activation of the superior colliculus on saccades in monkeys. Journal of Neurophysiology, 93: 519-534.

Saito Y, Isa T (2005) Organization of interlaminar interactions in the rat superior colliculus. Journal of Neurophysiology, 93:2898-2907.

Sooksawate T, Saito Y, Isa T Electrophysiological and morphological properties of identified crossed tecto-reticular neurons in the rat superior colliculus. Neuroscience Research, 52:174-184.

■ 2004年
Alstermark B, Ogawa J, Isa T (2004) Lack of monosynaptic corticomotoneuronal excitation in the adult rat: fast disynaptic excitation is mediated via reticulospinal neurones and slow polysynaptic excitation via segmental interneurons. Journal of Neurophysiology, 91:1832-1839.

Yamashita T, Isa T (2004) Enhancement of excitatory postsynaptic potentials by preceding application of acetylcholine in mesencephalic dopamine neurons. Neuroscience Research 49: 91-100.

Sakatani T, Isa T (2004) PC-based high-speed video-oculography for measuring rapid eye movements in mice. Neuroscience Research, 49:123-131.

Tanaka H, Ono K, Shibasaki H, Isa T, Ikenaka K (2004) Conduction properties of identified neural pathways in the central nervous system of mice in vivo. Neuroscience Research, 49:113-122.

Saitoh K, Isa T, Takakusaki K (2004) Nigral GABAergic inhibition upon mesencephalic dopaminergic cell groups in rats. European Journal of Neuroscience, 19:2399-2409.

Saito Y, Isa T (2004) Laminar specific distribution of lateral excitatory connections in the rat superior colliculus. Journal of Neuophysiology, 92:3500-3510.

Sasaki S, Isa T, Pettersson L-G, Alstermark B, Naito K, Yoshimura K, Seki K, Ohki Y (2004) Dexterous finger movements in primate without monosynaptic corticomotoneuronal excitation. Journal of Neurophysiology, 92:3142-3147.

Li F, Endo T, Isa T (2004) `Presynaptic muscarinic acetylcholine receptors suppress GABAergic synaptic transmission in the intermediate gray layers of mouse superior colliculus. European Journal of Neuroscience, 20:2079-2088.

Isa T & Kobayashi Y (2004) Switching between cortical and subcortical sensorimotor pathways. In Progress in Brain Research "Brain Mechanisms for the integration of posture and movement". (eds. Mori S, Stuart DG, Wiesendanger M) 143:299-305.

Kobayashi Y, Inoue Y & Isa T (2004) Pedunculo-pontine control of visually guided saccades. In Progress in Brain Research "Brain Mechanisms for the integration of posture and movement". (eds. Mori S, Stuart DG, Wiesendanger M) 143:439-445.

Isa T, Inoue Y, Kobayashi Y (2004) Cognitive function of the brainstem cholinergic system. In International Congress Series 1250 "Cognition and Emotion in the Brain" (eds. Ono T, Matsumoto G, Llinas R, Berthoz A, Norgren R, Nishijo H, Tamura R), pp397-406.
■ 2003年
Saito Y, Isa T (2003) Local excitatory network and NMDA receptor activation generate a synchronous and non-linear bursting command from the superior colliculus. Journal of Neuroscience, 23:5854-5864.

Seki K, Perlmutter SI, Fetz EE (2003) Sensory input to primate spinal cord is presynaptically inhibited during voluntary movement. Nature Neuroscience 6:1309-1316.

Katsuta H, Isa T (2003) Release from GABAA receptor-mediated inhibition unmasks interlaminar connection within superior colliculus in anesthetized adult rats. Neuroscience Research, 46:73-83.

Yamashita T, Isa T (2003) Fulfenamic acid sensitive, Ca2+-dependent inward current induced by nicotinic acetylcholine receptors in dopamine neurons. Neuroscience Research, 46:463-473.

Endo T, Yanagawa Y, Obata K, Isa T (2003) Characteristics of GABAergic neurons in the superficial superior colliculus. Neuroscience Letters, 346:81-84.

Yamashita T, Isa T (2003) Ca2+-dependent inward current induced by nicotinic receptor activation depends on Ca2+/calmodulin-CaMKII pathway in dopamine neurons. Neuroscience Research, 47: 225-232.

Saitoh K, Hattori S, Song W-J, Isa T, Takakusaki K (2003) Nigral GABAergic inhibition upon cholinergic neurons in the rat pedunculopontine tegmental nucleus. European Journal of Neuroscience, 18: 879-886.

Isa T, Kobayashi Y, Saito Y (2003) Dynamic modulation of signal transmission in the local circuit of mammalian superior colliculus. In "The Superior Colliculus: New Approaches for Studying Sensorimotor Integration." (eds. W.C. Hall & A. K. Moschovakis), CRC Press, pp159-171.

伊佐 正(2003)「上丘による眼球運動制御」脳の科学 第25巻7号

伊佐 正(2003)「空間をめぐる中枢座標系」Equilibrium Research vol 62; 18-26.
■ 2002年
Kobayashi Y, Inoue Y, Yamamoto M, Isa T, Aizawa H (2002) Contribution of pedunculopontine tegmental nucleus neurons to performance of visually guided saccade tasks in monkeys. Journal of Neurophysiology, 88:715-731.

EndoT, Isa T (2002) Postsynaptic and presynaptic GABAB receptor-mediated inhibition in rat superficial superior colliculus neurons. Neuroscience Letters 322: 126-130.

Isa T, Sasaki S (2002) Brainstem control of head movements during orienting; organization of the premotor circuits. Progress in Neurobiology, 66: 205-241.

Alstermark B, Isa T (2002) Premotoneuronal and direct corticomotoneuronal control in the cat and macaque monkey. In "Movement and Sensation" (eds. Gandevia S, Proske U), Adv Exp Med Biol. 2002;508:281-297.

Kobayashi Y, Isa T (2002) Sensory-motor gating and cognitive control by the brainstem cholinergic system. Neural Networks 15:731-741.

Isa T (2002) Intrinsic processing in the mammalian superior colliculus. Current Opinion in Neurobiology, 12:668-677.
■ 2001年
Endo T, Isa T (2001) Functionally different AMPA-type glutamate receptors in morphologically identified neurons in superficial layer of rat superior colliculus. Neuroscience, 108: 129-141.

Kobayashi Y, Saito Y, Isa T (2001) Facilitation of saccade initiation by brainstem cholinergic system. Brain Development, 23 S24-S27.

Isa T, Saito Y (2001) The direct visuo-motor pathway in mammalian superior colliculus; novel perspective on the interlaminar connection. Neuroscience Research, (update article) 41: 107-113.
■ 2000年
Saito Y, Isa T (2000) Voltage-gated transient outward currents neurones with different firing properties in rat superior colliculus. Journal of Physiology (London), 528: 91-105.

Tsuzuki K, Isa T, Ozawa S (2000) Subunit composition of AMPA receptors expressed by single hippocampal neurons. Neuroreport 11:3583-3587.

伊佐 正 (2000) 注意の脳内表現へのボトムアップ的アプローチ。 VISION vol 12, No.3 123-130
■ 1999年
Aizawa H, Kobayashi Y, Yamamoto M, Isa T (1999) Injection of nicotine into the superior colliculus facilitates occurrence of express saccades in monkeys. Journal of Neurophysiology 82: 1642-1646.

Saito Y, Isa T (1999) Electrophysiological and morphological properties of neurons in the rat superior colliculus. I. Neurons in the intermediate layer. Journal of Neurophysiology 82: 754-767.

Sasaki S, Isa T, Naito K (1999) Effects of lesion of pontomedullary reticular formation on visually triggered vertical and oblique head orienting movements in alert cats. Neuroscience Letters. 265: 13-16.

Alstermark B, Isa T, Ohki Y, Saito Y. (1999) Disynaptic pyramidal excitation in forelimb motoneurons mediated via C3-C4 propriospinal neurons in the macaca fuscata. Journal of Neurophysiology, 82: 3580-3585.

Isa T, Sasaki S (1999) Neural mechanisms for the control of visually guided orienting movements of the head. In : "Motor Control Today and Tomorrow (ed. G.N. Gantchev, S. Mori, J. Massion, Academic Publishing House "Prof. M. Drinov, Sofia)", pp57 - 69.

Isa T (1999) A role of brainstem acetylcholinergic system in regulating initiation of saccadic eye movements. In : "From Basic Motor Control to Functional Recovery" (eds. N. Gantchev & G.N. Gantchev), pp19−23.

伊佐 正 (1999) 上丘へのコリン作動性投射の生理的役割。 Brain Medical vol 11 p27 - 33.
■ 1998年
Isa T, Endo T, Saito Y (1998) The visuo-motor pathway in the local circuit of the rat superior colliculus. Journal of Neuroscience 18: 8496-8504.

伊佐 正 (1998) 視覚座標から運動座標へ−感覚・運動情報変換機構。平衡神経科学 (Equilibrium Research),57:pp343-352.
■ 1997年
Itazawa S, Isa T, Ozawa S (1997) Inwardly rectifying and Ca2+- permeable AMPA-type glutamate receptor channels in rat neocortical neurons. Journal of Neurophysiology, 78:2592-2601.

Pettersson L-G, Lundberg A, Alstermark B, Isa T, Tantisira B (1997) Effect of spinal cord lesions on forelimb target-reaching and on visually guided switching of target-reaching in the cat. Neuroscience Research, 29:241-256.
■ 1996年
Isa T, Itazawa S, Iino M, Tsuzuki K, Ozawa S (1996) Distribution of neurones expressing inwardly rectifying and Ca2+-permeable AMPA receptors in rat hippocampal slices. Journal of Physiology. (London) 491 : 719 - 733.

Iino M, Koike M, Isa T, Ozawa S (1996) Voltage dependent blockage of Ca2+- permeable AMPA receptors by Joro spider toxin in cultured rat hippocampal neurones. Journal of Physiology (London) 496: 431-437.

Tantisira B, Alstermark B, Isa T, Kummel H, Pinter M (1996) Motoneuronal projection pattern of single C3-C4 propriospinal neurones. Canadian Journal of Physiology & Pharmacology 74:518-530.

Isa T, Iino M, Ozawa S (1996) Spermine blocks synaptic transmission mediated by Ca2+- permeable AMPA receptors. Neuroreport 7: 689-692.

Ozawa S, Isa T, Tsuzuki K, Iino M (1996) Ca2+ permeability and subunit composition of AMPA receptors in hippocampal neurons. In : "Integrative and Molecular Approach to Brain Function." (eds) Ito M, Miyashita Y, Elsevier, Amsterdam, pp47-56.

 伊佐 正 教授 
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