部門公開セミナー
日 時 | 2013年12月19日 16:00~17:00 |
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場 所 | 山手2号館2階西 セミナー室 |
演 者 | Dr. Keigo Kohara(Picower Institute for Learning and Memory at MIT, U.S.A.) |
演 題 | New hippocampal anatomy by optogenetics 海馬新解剖学 "オプトジェネティクスによる新展開" |
要 旨 | Formation of episodic memory requires precise information routing in the hippocampus. For more than a hundred years, the trisynaptic circuit has been considered the main anatomical substrate of the hippocampal circuitry responsible for learning and memory. However, the hippocampus includes a region located between CA3 and CA1, named “CA2”, whose intrahippocampal connectivity has remained elusive. Here, by using cell type-specific transgenic mice, viral tracers, optogenetics and patch-clamp recordings we examined CA2 circuits in the hippocampus. Our findings redefine hippocampal functional anatomy, allowing a deeper understanding of the biology of learning and memory. |
連絡先 | Yoshiyuki Kubota, Ph.D. |