部門公開セミナー

日 時 2013年12月19日 16:00~17:00
場 所 山手2号館2階西 セミナー室
演 者 Dr. Keigo Kohara(Picower Institute for Learning and Memory at MIT, U.S.A.)
演 題 New hippocampal anatomy by optogenetics 海馬新解剖学 "オプトジェネティクスによる新展開"
要 旨

Formation of episodic memory requires precise information routing in the hippocampus. For more than a hundred years, the trisynaptic circuit has been considered the main anatomical substrate of the hippocampal circuitry responsible for learning and memory. However, the hippocampus includes a region located between CA3 and CA1, named “CA2”, whose intrahippocampal connectivity has remained elusive. Here, by using cell type-specific transgenic mice, viral tracers, optogenetics and patch-clamp recordings we examined CA2 circuits in the hippocampus. Our findings redefine hippocampal functional anatomy, allowing a deeper understanding of the biology of learning and memory.

連絡先 Yoshiyuki Kubota, Ph.D.