部門公開セミナー
日 時 | 2015年02月09日 16:00~17:00 |
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場 所 | 山手地区2号館西2階セミナー室 |
演 者 | Prof. Yi Zuo(University of California, Santa Cruz, USA) |
演 題 | Synapse reorganization in the living brain |
要 旨 | One fundamental question in neuroscience is how the brain processes and stores information. As the information-processing elements in the brain, neurons communicate via specialized connections called synapses. The majority of excitatory synapses reside at dendritic spines, which serve as a good proxy for synaptic connectivity. Using transcranial two-photon microscopy to visualize fluorescently-labeled neurons in transgenic mice, our recent studies followed the dynamics of spines on apical dendrites of L5 pyramidal neurons in the living brain. In this talk, I will discuss our findings on the spatiotemporal changes of spine dynamics during motor-skill learning. I will also present our new data exploring the molecular/cellular mechanisms underlying activity-dependent spine pruning during development. |
連絡先 | Yoshiyuki Kubota (yoshiy@nips.ac.jp) |