The general objective of the project is to understand how withdrawal early affective memories are encoded and retrieved (or reactivated) in opiate addiction, and how these memories may affect the behaviour of the individuals. These processes will be analyzed by combining behavioural, cellular and in vivo electrophysiological analyses in behaving animals. A special attention is paid to interconnected limbic structures (amygdala, accumbens, prefrontal cortex), which we hypothesize from our previous works as being crucial in these processes (Frenois et al., 2005, J. Neuroscience). Requirements: The candidate must have a PhD in Neuroscience with an advanced expertise in electrophysiological recordings in behaving animals and less than 5 years of post-doctoral experience. Compulsory basic knowledge: multiple electrode recording and analysis, programming in CC++, Python, Delphi, Matlab or similar.
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