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2 細胞器官研究系

2.1 生体膜研究部門

A. 英文原著

  1. Fukata Y, Lovero KL, Iwanaga T, Watanabe A, Yokoi N, Tabuchi K, Shigemoto R, Nicoll RA, Fukata M (2010) Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. Proc Natl Acad Sci USA 107:3799-3804.
  2. Shmueli A, Segal M, Sapir T, Tsutsumi R, Noritake J, Bar A, Sapoznik S, Fukata Y, Orr Y, Fukata M, Reiner O (2010) Ndel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity. EMBO J 29:107-119.

C. 英文総説(査読あり)

  1. Fukata Y, Fukata M (2010) Protein palmitoylation in neuronal development and synaptic plasticity. Nat Rev Neurosci 11:161-175.

D. 研究関係著作

  1. 横井紀彦, 深田正紀, 深田優子 (2010) シナプス伝達修飾分子LGI1の機能異常による“てんかん”発症. Medical Bio 7:40-47.
  2. 岩永剛, 深田正紀, 深田優子 (2010) LGI1が仲介するタンパク質複合体の破綻はシナプス伝達異常とてんかんを引き起こす. 細胞工学 29:594-595.

2.2 機能協関研究部門

A. 英文原著

  1. Subramanyam M, Takahashi N, Hasegawa Y, Mohri T, Okada Y (2010) Inhibitionof a protein kinase Akt1 by apoptosis signal-regulating kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase. J Biol Chem 285:6109-6117.
  2. James AF, Sabirov RZ, Okada Y (2010) Clustering of protein kinase A-dependent CFTR chloride channels in the sarcolemma of guinea-pig ventricular myocytes. Biochem Biophys Res Commun 391:841-845.
  3. Ohbuchi T, Sato K, Suzuki H, Okada Y, Dayanithi G, Murphy D, Ueta Y (2010) Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus. J Physiol 588:2147-2162.
  4. Inoue H, Takahashi N, Okada Y, Konishi M (2010) Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice. Am J Physiol Cell Physiol 298:C900-C909.
  5. Kurbannazarova RSh, Okada Y, Merzlyak PG, Tashmukhamedov BA, Sabirov RZ (2010) Characteristics of anion channel of intermediate conductance activated at the membrane of thymocytes under hypoosmotic stress. Uzbekistan Biol J 3:3-7 (in Russian).
  6. Koizumi A, Takayasu M, Takayasu H (2010) Asymmetric inhibitory connections enhance directional selectivity in a three-layer simulation model of retinal networks. J Integr Neurosci 9:337-350.
  7. Moritoh S, Tanaka KF, Jouhou H, Ikenaka K, Koizumi A (2010) Organotypic tissue culture of adult rodent retina followed by particle-mediated acute gene transfer in vitro. PLoS One 5:e12917. doi: 1371/journal.pone.0012917
  8. Sato K, Numata T, Saito T, Ueta Y, Okada Y (2010) V2 receptor-mediated autocrine role of somato-dendritic release of AVP in rat vasopressin neurons under hypoosmotic conditions. Sci Signal (in press).

2.3 細胞生理研究部門>

A. 英文原著

  1. Uchida K, Shiuchi T, Inada H, Minokoshi Y, Tominaga M (2010) Metabolic adaptation of mice in a cool environment. Pflüger Archiv Eur J Physiol 459:765-774.
  2. Shibasaki K, Murayama N, Ono K, Ishizaki Y, Tominaga M (2010) TRPV2 enhances axon outgrowth through its activation by membrane stretch in developing sensory and motor neurons. J Neurosci 30:4601-4612.
  3. Fujita F, Azuma T, Tajiri M, Okamoto H, Sano M, Tominaga M (2010) Significance of hair-dye base-induced sensory irritation. Int J Cosmet Sci 32:217-224.
  4. Kawaguchi H, Yamanaka A, Uchida K, Shibasaki K, Sokabe T, Maruyama Y, Yanagawa Y, Murakami S, Tominaga M (2010) Activation of polycystic kidney disease-2-like 1 (PKD2L1)/PKD1L3 complex by acid in mouse taste cells. J Biol Chem 285:17277-17281.
  5. Sokabe T, Fukumi-Tominaga T, Yonemura S, Mizuno A, Tominaga M (2010) The TRPV4 channel contributes to intercellular junction formation in keratinocytes. J Biol Chem 285:18749-18758.
  6. Kohno K, Sokabe T, Tominaga M, Kadowaki T (2010) Honey bee thermal/chemical sensor, AmHsTRPA, reveals neofunctionalization and loss of Transient Receptor Potential channel genes. J Neurosci 30:12219-12229.
  7. Yamanaka A, Tabuchi S, Tsunematsu T, Fukazawa Y, Tominaga M (2010) Direct interaction between orexin neurons activates these neurons through the OX2R. J Neurosci 30:12642-12652.
  8. Mihara H, Boudaka A, Shibasaki K, Yamanaka A, Sugiyama T, Tominaga M (2010) Involvement of TRPV2 activation in intestinal movement through NO production in mice. J Neurosci 30:16536-16544.

C. 英文総説(査読有り)

  1. Yamanaka A, Tsunematsu T (2010) New approaches for the study of orexin function. J. Neuroendocrinol. 22: 818-824.

D. 研究関係著作

  1. 富永真琴 (2010) 侵害刺激受容に関わるtransient receptor potential vanilloid 1 (TRPV1)及びtransient receptor potential ankyrin 1 (TRPA1)の活性化, 制御メカニズム. 薬学雑誌 130:289-294.
  2. 富永真琴 (2010) TRPチャネルを介した温度受容の分子機構. アレルギーと神経ペプチド 6:39-46.
  3. 曽我部隆彰, 富永真琴 (2010) 膀胱伸展を感知するTRPV4チャネル. 医学のあゆみ 233:497.
  4. 富永真琴 (2010) 酸味受容のメカニズム —オフ応答を司る分子と生物学的意義—.　化学と生物 48:419-423.
  5. 富永真琴 (2010) TRPチャネルとバリア機能. アレルギー・免疫 17:53-59.
  6. 富永真琴 (2010) 温度受容の分子機構. “からだと温度の事典” (彼末一之 編), 朝倉書店, pp 19-22.
  7. 鈴木喜郎 (2010) カルシウム恒常性維持を担うTRPチャネル. 腎と透析 69:359-362.
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