Abstract

Download the abstract(protected.)
Oral session, click here
Poster session, click here

*)Password required for download.
Please contact 50th-sympo-regist@nips.ac.jp for password.

The abstract booklet will be distributed on the day.



Program

Registration:Dec 5th(Thu) 11:30- at OCC 1F Entrance Hall


Date : Dec 4(Wed)
 18:30-  Meet at the lobby (Grand Inn HIGASHI-OKAZAKI Hotel)
 19:00- Welcome Reception (for oversea speakers)

Date : Dec 5(Thu)
 Local symposium (2F Small Meeting Room)
8:50-11:20  Local symposium --- click here
 Main Symposium (Osumi Hall)
 12:50-  Opening Remark by Prof. Junichi Nabekura

Director General of NIPS

  Session 1 (Discussion Leaders: Motohiko Sato and Yukari Takeda)
 13:00-13:35  1. Rui Ping-Xiao  

Institute of Molecular Medicine, Peking University

Ca2+/calmodulin-dependent Kinase II and Cardiac Cell Death

 13:35-14:10  2. Jin Han  

College of Medicine, Cardiovascular and Metabolic Disease Center, Inje University

Molecular mechanism of exercise-induced cellular adaption

 14:10-14:40  3. Mitsuhiko Yamada

Shinshu University School of Medicine

A β arrestin-bias AT1 receptor agonist improves the survival of neonatal knock-in mice bearing a human dilated cardiomyopathy mutation

 14:40-15:10  4. Satomi Adachi-Akahane 

Graduate School of Medicine and Faculty of Medicine, Toho University

Ventricular diastolic dysfunction in the early stage of diabetic cardiomyopathy: involvement of insulin-mediated regulation of Ca2+ signaling

   Coffee Break (20 min)
  Session 2 (Discussion Leaders: Jin Han and Kazuho Sakamoto)
 15:30-16:05  5. David Carling  

MRC London Institute of Medical Sciences, Imperial College London

Investigating the role of AMPK activation in vivo

 16:05-16:35  6. Yasuhiko Minokoshi

Endocrinology and Metabolism, NIPS

AMPK is the metabolic sensor that induces dietary preference for carbohydrate over fat

 16:35-17:05  7. Ippei Shimizu

Niigata University Graduate School of Medical and Dental Sciences

Senometabolite promotes pathologies in cardiovascular disorders

 17:05-17:35  8. Wataru Kimura  

RIKEN Center for Biosystems Dynamics Research

Oxidative Metabolism and Cardiomyocyte Cell Cycle Regulation
 17:35-18:10  9. Ken Suzuki

William Harvey Research Institute / Queen Mary University of London

Myocardial repair, cardiac macrophages and mesenchymal stromal cell-based therapy

 18:30-  Dinner for invited speakers

Date : Dec 6(Fri)
 Session 3 (Discussion Leaders: Woong Sun and Takuro Numaga-Tomita)
 9:00-9:30 

1. Junko Kurokawa  

University of Shizuoka, School of Pharmaceutical Sciences

Multidisciplinary approaches for functional evaluation of human iPS-derived cardiomyocytes

 9:30-10:00  2. Yasunari Kanda  

National Institute of Health Sciences (NIHS)

Development of in vitro cardiotoxicity assessment using human iPS cell technology

 10:00-10:30  3. Satoshi Matsuoka  

Faculty of Medical Sciences, University of Fukui

Property and roles of mitochondrial Na+-Ca2+ exchange in heart

   Group Photo (at the entrance of OCC)
   Coffee Break (25 min)
   Session 4 (Discussion Leaders: Satomi Adachi-Akahane and Akiyuki Nishimura)
 10:55-11:25  4. Yoshihiro Ishikawa  

Yokohama City University School of Medicine

Mechanical Stress and Vascular Regeneration

 11:25-12:00  5. Sang Geon Kim  

Seoul National University, College of Pharmacy

G12/G13 regulation of systemic energy metabolism

 12:00-12:30  6. Hitoshi Kurose

Graduate School of Pharmaceutical Sciences, Kyushu University

G12 family G protein-mediated signaling

   Poster viewing (with lunch)
  Session 5 (Discussion Leaders: Ippei Shimizu and Taichiro Tomida)
 13:30-14:05  7. SookJa Kim Chung  

Faculty of Medicine, Macau University of Science and Technology

   The study of Epac, exchange protein directly activated by cAMP, in the pathogenesis of cerebral ischemia
 14:05-14:35  8. Utako Yokoyama

Tokyo Medical University

Prostaglandin E receptor EP4-mediated regulation of vascular elasticity

 14:35-15:05  9. Hisao Yamamura 

Graduate School of Pharmaceutical Sciences, Nagoya City University

Pathophysiological significance of TRPC6 channels in pulmonary arterial hypertension

   Coffee Break (15 min)
  Session 6 (Discussion Leaders: David Carling and Kazuhiro Nishiyama)
 15:20-15:50  10. Keiji Kuba 

Akita University Graduate School of Medicine

mRNA deadenylation-mediated control of cardiac homeostasis

 15:50-16:20  11. Mariko Omatsu-Kanbe  

Shiga University of Medical Science

Identification of ANP-marked cardiac progenitor cells in mouse heart that develop into beating cells

 16:20-16:50  12. Shigeki Kiyonaka  

Graduate School of Engineering, Nagoya University

Coordination chemogenetics, a new technique for allosteric regulation of membrane receptors

 17:00-18:00  Flash talk by poster presenters  (17:00 pm ~ 18:00 pm)
18:00-     Poster viewing & Get-together

Date : Dec 7(Sat)

Session 7 (Discussion Leader: Nobuhiko Ohno)

 9:00-9:30   1: Akiyuki Nishimura 

Graduate School of Pharmaceutical Sciences, Kyushu University

Pathology-dependent aberrant interaction between mitochondria and actin cytoskeleton causes cardiac fragility

 9:30-10:05   2: Woong Sun  

Korea University College of Medicine

Mitochondrial quality surveillance by Drp1-dependent regulation of mitochondrial structure and function

    Coffee Break (10 min)
 Session 8 (Discussion Leaders: Yasunari Kanda and Nobuhiko Ohno)
 10:15-10:45   3: Seiryo Sugiura  

UT-Heart Inc

A Heart simulator coupling the molecular dynamics with the finite element model – Cross-scale integration of our knowledge on heart

 10:45-11:20   4: Hyoung Kyu Kim

Cardiovascular and Metabolic Disease Center, Inje University

Tetrahydrobiopterin rescues late-stage diabetic heart failure via restoring mitochondria function through CaMKK2/CREB/PGC1-α signaling

 11:20-11:50   5: Junken Aoki  

Graduate School of Pharmaceutical Sciences, Tohoku University

Lysophospholipid Signaling Protects the Heart from Ischemic Damage by regulating the Vagal Nerve

Closing Remark (by Motohiro Nishida)





Poster
 P1   Activation of Ca2+ activated K+ channel enhances hypertrophy of C2C12 myotubes via Akt/PI3K pathway
Kazuho Sakamoto, Chihiro Hibi, Taito Kuwahara, Junko Kurokawa
 P2   Estrogens modify profile of hERG block in the heart
Shintarou Sugimoto, Fumiya Tamura, Nanami Iewasaki, Masaki Ieda,Kazuho Sakamoto and Junko Kurokawa
 P3 Noninvasive evaluation of cardiac types of iPS-derived cardiomyocytes using cell motion imaging
Momoka Nakagawa, Yui Suzuki, Yusuke Sano, Masahiko Yamaguchi, Kazuho Sakamoto, Junko Kurokawa
 P4   TRPC3-Nox2 complex formation mediates nutritional deficiency-induced cardiomyocyte atrophy
Tomohiro Tanaka, Suhaini Binti Sudi, Sayaka Oda, Kazuhiro Nishiyama, Akiyuki Nishimura, Caroline Sunngip, Superchoke Mangmool, Takuro Numaga-Tomita and Motohiro Nishida
 P5   Depolysulfidation of Drp1 increases cardiac vulnerability to hemodynamic overload
Akiyuki Nishimura, Tomohiro Tanaka, Kakeru Shimoda, Kazuhiro Nishiyama, Motohiro Nishida
 P6   Identification of a novel TRPC3-Nox2 complex inhibitor that attenuates anthracycline-induced cytotoxicity
Kazuhiro Nishiyama, Tomohiro Tanaka, Chiemi Toyama, Akiyuki Nishimura, Motohiro Nishida
 P7   Cigarette sidestream smoke induces mitochondrial fission-associated myocardial early senescence
Daiki Tomokiyo, Takumi Goto, Akiyuki Nishimura, Kazuhiro Nishiyama, Tomohiro Tanaka, Motohiro Nishida
 P8   Identification of G protein-coupled receptors that induce ligand-independent calcium oscillations
Kosuke Sakata, Kazuhiro Nishiyama, Tomohiro Tanaka, Asuka Inoue, Junken Aoki,  Akiyuki Nishimura, Motohiro Nishida
 P9   Analysis of the molecular mechanism underlying STIM1-dependent suppression of CaV1.2
Takuro Numaga-Tomita, Hiroki Takahashi, Motohiro Nishida, and Mitsuhiko Yamada
 P10   Physiological role of gp130 receptor in newborn mouse cardiomyocyte development
Hiroyuki Kawagishi, Tsutomu Nakada, Takuro Numaga-Tomita, Mitsuhiko Yamada
 P11   Cardiac Mitofusin-1 is Reduced in Non-responding Patients with Heart Failure
Yung-Ting Hsiao, Ippei Shimizu, Takayuki Wakasugi, Shuang Jiao, Tohru Watanabe, Takeshi Kashimura, Yohko Yoshida, Haruo Hanawa, Kazuyuki Ozaki, Tohru Minamino
 P12   Contribution of TMEM16A Ca2+-activated Cl- channels to cell proliferation and migration in brain capillary endothelial cells
Takahisa Suzuki, Miki Yasumoto, Yoshiaki Suzuki, Kiyohumi Asai, Yuji Imaizumi, Hisao Yamamura
 P13  MRTF-Aexpressed in macrophages drives progression of atherosclerosis
Jianbo An, Taeko Naruse, Kunihiko Hinohara, Yurie Soejima, Motoji Sawabe, Yasuaki Nakagawa, Koichiro Kuwahara, Keiji Kuba, Akinori Kimura
 P14   Protective roles of CNOT6L deadenylase in pressure overload-induced cardiac remodeling
Tomokazu Yamaguchi, Teruki Sato, Takafumi Minato, Jianbo An, Midori Hoshizaki, Hiroyuki Watanabe, Yumiko Imai, Tadashi Yamamoto, Keiji Kuba
 P15   The suppression of Orai1-mediated Ca2+ entry causes oxidative stress-induced cell death in brain capillary endothelial cells.
Hideto Yamamura, Yoshiaki Suzuki, Kiyofumi Asai, Yuji Imaizumi, and Hisao Yamamura
 P16   Difference in Early-phase Ca2+ Transients of Guinea-Pig Pulmonary Vein Cardiomyocytes Compared with Atrial and Ventricular Cardiomyocytes
Iyuki Namekata, Ryosuke Odaka, Haruhito Hiiro, Tamano Ohmori, Shogo Hamaguchi, Hikaru Tanaka
 P17   LRRC26 regulates BK channel function in bronchial smooth muscle cells
Sayuri Noda, Yoshiaki Suzuki, Hisao Yamamura, Wayne R. Giles, Yuji Imaizumi
 P18   The possibility of DIF-1 as a therapeutic agent for liver fibrosis by controling the transdifferentiation of hepatic stellate cells
Momoka Yamaguchi, Akira Ooka, Shohei Furukawa, Syn-ya Saito, Tomohisa Ishikawa.
 P19   Are hepatic stellate cells involved in the regulation of liver blood flow by the sympathetic nerve?
Naoki Dohi, Kyosuke Iwami, Momoka Yamaguchi, Sin-ya Saito, Tomohisa Ishikawa
 P20   Cardiovascular functions of tissue-specific transgenic mice expressing dominant negative TRPM7 mutant
Takayuki Nemoto, Hideaki Tagashira, Tomo Kita, Tomohiro Numata, Satomi Kita, Takahiro Iwamoto
 P21   Inhibitory regulation of P2X7-mediated ATP signaling by caveolin-1 in pro-inflammatory macrophages
Yuuki Sawai, Yoshiaki Suzuki,Yuji Imaizumi, Hisao Yamamura
 P22   PDGF upregulates Ca2+-sensing receptors via PDGF-STAT signals in pulmonary arterial smooth muscle cells
Aya Yamamura, Md Junayed Nayeem, Rie Takahashi, Abdullah Al Mamun, Hisaki Hayashi, Motohiko Sato
 P23   Physiological role of TRPC6 in regulation of cardiovascular system
Sayaka Oda,Supachoke Mangmool,Tomohiro,Tanaka,Kazuhiro,Nishiyama, Akiyuki Nishimura, Motohiro Nishida
 P24   Mitochondria are involved in automaticity of murine sinoatrial nodal cells
Yukari Takeda, and Satoshi Matsuoka
 P25   Species difference of the hyperpolarized-activated current in pulmonary vein cardiomyocytes.
Daichi Takagi, Yosuke Okamoto, Takayoshi Ohba, Hiroshi Yamamoto, Kyoichi Ono
 P26   Vascular smooth muscle NCX1 is involved in the development of hypoxia-induced pulmonary arterial hypertension
Hideaki Tagashira, Asahi Nagata, Satomi Kita, Tomo Kita, Akinori Iwasaki, Kohtaro Abe, Takahiro Iwamoto
 P27   The role of P2Y6R in cardiovascular homeostasis
Kakeru Shimoda, Kazuhiro Nishiyama,Akiyuki Nishimura, Tomohiro Tanaka, Motohiro Nishida
 P28   Molecular mechanisms of TRPM7 inhibition by oxidative stress
Hana Inoue, Takashi Murayama, Masato Konishi, Michiko Tashiro, and Utako Yokoyama
 P29   Possibility of exercise therapy as a new treatment for cancer patients with cardiac dysfunction by cachexia
Miki Nonaka, Susumu Ueno, Ryo Kakigi, Nagomi Kurebayashi, Takashi Murayama, Kiyoshi Terawaki, Takashi Sakurai, Yasuhito Uezono
 P30   Regulation mechanisms of G-protein-gated inwardly rectifying K+ channel by small molecules
I-Shan Chen, Chang Liu, Michihiro Tateyama, Izhar Karbat, Motonari Uesugi, Eitan Reuveny, Yoshihiro Kubo
 P31   Lethal arrhythmias caused by subcellular expression abnormality as the loss-of-function of Na+ channel: a simulation study
Kunichika Tsumoto, Yu-ichi Kuda, Mamoru Tanida, Yasutaka Kurata
 P32   Regulation of hepatic glucose metabolism by voltage-gated proton channels (VSOP/Hv1) of Kupffer cells
Takafumi Kawai, Kento Kayama, Shoki Tatsumi, Nana Miyawaki, Yoshifumi Okochi, Manabu Abe, Kenji Sakimura, Hiroyasu Yamamoto, Shinji Kihara, Yasushi Okamura.
 P33   IL-1βdecreases TEA-sensitive potassium channels in mouse articular chondrocytes
Shinya Tateno, Yoshiaki Suzuki, Yuji Imaizuki, Hisao Yamamura
 P34   Loss of GPR4, proton-sensing GPCR, improves cardiac function and inflammation after myocardial infarction
Ryusei Ogino, Shunta Itoh, Kenji Watari, Akiomi Nagasaka, Michio Nakaya, Chihiro Mogi, Fumikazu Okajima, Hitoshi Kurose
 P35   The role of serine, a non-essential amino acid, in the production of cytokines in macrophages
Hiroya Ohta, Kento Kurita, Ibuki Shirakawa, Ayaka Ito, Miyako Tanaka, Hiroshi Arima, Yoshihiro Ogawa, Takayoshi Suganami
 P36   Dynamical mechanisms of early afterdepolarizations in ventricular myocytes of long QT syndromes: insights from bifurcation analysis of mathematical models
Yasutaka Kurata, Kunichika Tsumoto, Yuichi Kuda, Mamoru Tanida
 P37   The molecular mechanism of the Ca2+ signaling defects underlying ventricular diastolic dysfunction in diabetic cardiomyopathy
Yoshinori Mikami, Masanori Ito, Taichiro Tomida, Daisuke Ohshima and Satomi Adachi-Akahane
 P38  Voltage-dependence of ICaL blockade in non-selective IKr blockers underlies their opposite effects on early afterdepolarization in drug-induced arrhythmia  
Shingo Murakami, Akira Kimura
 P39   CD34 and PDGFRα+ double positive cells regulating spontaneous activities are dominantly expressed in serosa side in bladder outlet obstruction model
Shuchi Kajioka, Kareman Eljamal, Mitsuho Onimaru, Kentaro Kawagoe and Toshiyuki Sasaguri
 P40   Direct detection of intramolecular dynamics of membrane proteins using X-ray based analysis techniques
Kazuhiro Mio , Shoko Fujimura , Masaki Ishihara , Muneyo Mio , Masahiro Kuramochi , Hiroshi Sekiguchi , Tai Kubo , Yuji C. Sasaki





 Copyright(C) 2019 NIPS All Right Reserved.