2023
Neurons in the deepest part of the neocortex alter their functions with sensory experience
The functional roles of the surviving subplate neurons remain largely unknown. We performed two-photon Ca2+ imaging from L6b neurons with post hoc 3D immunohistochemistry of a sublate neuron marker. L6b/ surviving subplate neurons in V1 showed clear responses to visual stimuli. Chronic two-photon imaging showed that L6b neurons exhibited ocular dominance plasticity. These results indicate that surviving subplate neurons exhibit sensory responses and experience-dependent plasticity.
February 21, 2023