2 細胞器官研究系

2.1 生体膜研究部門

A. 英文原著

  1. Tsutsumi R, Fukata Y, Noritake J, Iwanaga T, Perez F & Fukata M (2008) Identification of G-protein alpha subunit palmitoylating enzyme. Mol Cell Biol (in press).
  2. Ponimaskin E, Dityateva G, Ruonala MO, Fukata M, Fukata Y, Kobe F, Wouters FS, Delling M, Bredt DS, Schachner M & Dityatev A(2008) Fibroblast Growth Factor-Regulated Palmitoylation of the Neural Cell Adhesion Molecule Determines Neuronal Morphogenesis. J Neurosci 28:8897-8907.
  3. Greaves J, Salaun C, Fukata Y, Fukata M & Chamberlain LH(2008) Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein. J Biol Chem 283:25014-25026.

C. 英文総説(査読あり)

  1. Tsutsumi R, Fukata Y & Fukata M(2008) Discovery of protein-palmitoylating enzymes. Pflügers Arch-Eur J Physiol 456:1199-1206.

D. 研究関係著作

  1. 深田正紀, 深田優子(2008) AMPA型グルタミン酸受容体の動体制御機構. 日本神経精神薬理学雑誌 28:131-134.
  2. 堤良平, 深田優子, 深田正紀(2008) タンパク質S-パルミトイル化酵素. 生化学 (in press).

2.2 機能協関研究部門

A. 英文原著

  1. Numata T & Okada Y (2008) Molecular determinants of sensitivity and conductivity of human TRPM7 to Mg2+ and Ca2+. Channels 2:283-286.
  2. Numata T, Sato K, Okada Y & Wehner F (2008) Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis. Apoptosis 13:895-903.
  3. Lee EL, Hasegawa Y, Shimizu T & Okada Y (2008) IK1 channel activity contributes to cisplatin sensitivity of human epidermoid cancer cells. Am J Physiol Cell Physiol 294:C1398-C1406.
  4. Numata T & Okada Y (2008) Proton conductivity through the human TRPM7 channel and its molecular determinants. J Biol Chem 283:15097-15103.
  5. Liu H-T, Sabirov RZ & Okada Y (2008) Oxygen-glucose deprivation induces ATP release via maxi-anion channels in astrocytes. Purinergic Signal 4:147-154.
  6. Liu H-T, Toychiev AH, Takahashi N, Sabirov RZ & Okada Y (2008) Maxi-anion channel as a candidate pathway for osmosensitive ATP release from mouse astrocytes in primary culture. Cell Res 18:558-565.
  7. Dutta AK, Korchev YE, Shevchuk AI, Hayashi S, Okada Y & Sabirov RZ (2008) Spatial distribution of maxi-anion channel on cardiomyocytes detected by smart-patch technique. Biophys J 94:1646-1655.
  8. Shimizu T, Owsianik G, Freichel M, Flockerzi V, Nilius B & Vennekens R (2009) TRPM4 regulates migration of mast cells in mice. Cell Calcium (in press).

C. 英文総説(査読あり)

  1. Shimizu T, Lee EL & Okada Y (2008) Volume-sensitive Cl- channel as a regulator of acquired cisplatin resistance. Anticancer Res 28:75-84.
  2. Okada Y, Sato K, Toychiev AH, Suzuki M, Dutta AK, Inoue H & Sabirov RZ (2009) The puzzles of volume-activated anion channels. “Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases” (Eds. Alvarez-Leefmans FJ & Delpire E), Elsevier, San Diego (in press).
  3. Sabirov RZ & Okada Y (2009) The maxi-anion channel: A classical channel playing novel roles through an unidentified molecular entity. J Physiol Sci (in press).
  4. Okada Y, Sato K & Nuamta T (2009) Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel. J Physiol (in press).

E. その他

  1. 井上華, 岡田泰伸 (2008) 細胞内の水の調節. “水とからだの事典” (佐々木成, 石橋賢一 編), 朝倉書店, 東京, pp 292-299.

2.3 細胞生理研究部門

A. 英文原著
  1. Togashi K, Inada H & Tominaga M (2008) Inhibition of TRPM2 channels by 2-APB. Br J Pharmacol 153:1324-1330.
  2. Wang S, Dai Y, Fukuoka T, Yamanaka H, Kobayashi K, Obata K, Cui X, Tominaga M & Noguchi K (2008) PLC and PKA mediate bradykinin sensitization of TRPA1: a novel mechanism for inflammatory pain. Brain 131:1241-1251.
  3. Xing H, Ling JX, Chen M, Johnson RD, Tominaga M, Wang CY & Gu J (2008) TRPM8 mechanism of autonomic nerve response to cold in respiratory airway. Mol Pain 4:22.
  4. Inada H, Kawabata F, Ishimaru Y, Fushiki T, Matsunami H & Tominaga M (2008) Off-response property of an acid-activated cation channel complex PKD1L3/PKD2L1. EMBO R 9:690-697.
  5. Urisu T, Asano T, Zhang Z, Uno H, Tero R, Junkyu H, Hiroko I, Arima Y, Iwata H, Shibasaki K & Tominaga M (2008) Incubation type Si-based planar ion channel biosensor. Ana Bioanal Chem 391:2703-2709.
  6. Sokabe T, Tsujiuchi S, Kadowaki T & Tominaga M (2008) Drosophila Painless is a Ca2+-requiring channel activated by noxious heat. J Neurosci 28:9929-9938.
  7. Katanosaka K, Banik RK, Giron R, Higashi T, Tominaga M & Mizumura K (2008) Contribution of TRPV1 to the bradykinin-evoked nociceptive behavior and excitation of cutaneous sensory neurons. Neurosci Res 62:168-175.
  8. Fujita F, Uchida K, Moriyama T, Shima A, Shibasaki K, Inada H, Sokabe T & Tominaga M (2008) Intracellular alkalization causes pain sensation through activation of TRPA1. J Clin Invest 118:4049-4057.
D. 研究関係著作
  1. 富永真琴 (2008) 辛味の化学構造とレセプター. “トウガラシ-辛味の科学-” (岩井和夫, 渡辺達夫 編), 幸書房, 東京, pp 68-82.
  2. 稲田 仁, 富永真琴 (2008) TRPチャネルによるインスリン分泌制御. “分子糖尿病学の進歩 2008” (清野進, 渥美義仁, 門脇孝, 春日雅人 編), 金原出版, 東京, pp 8-14.
  3. 富永真琴 (2008) cyclic ADP-riboseによるTRPM2の活性化とインスリン分泌. 内分泌・糖尿病科 25:273-278.
  4. 富永真琴 (2008) 炎症性疼痛におけるTRPイオンチャネルの役割. ペインクリニック 29:179-188.
  5. 富永真琴 (2008) カプサイシン受容体TRPV1. Brain Nerve 60:493-501.
  6. 柴崎貢志, 富永真琴 (2008) 神経系のTRPチャネルと体温. Clinical Neuroscience 26:714-715.
  7. 稲田仁, 富永真琴 (2008) 酸っぱさと唾液の不思議な関係:薄まっても続く酸っぱっさ. Medical Bio 9月号 10-11.
  8. 富永真琴 (2008) 侵害刺激受容体. 生体の科学 59:424-425.