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7 行動・代謝分子解析センター

7.1 遺伝子改変動物作製室

A. 英文原著
  1. Hirabayashi M, Yoshizawa Y, Kato M, Tsuchiya T, Nagao S, Hochi S (2009) Availability of subfertile transgenic rats expressing c-myc gene as recipients for spermatogonial transplantation. Transgenic Res 18:135-141.
  2. Abdalla H, Hirabayashi M, Hochi S (2009) The ability of freeze-dried bull spermatozoa to induce calcium oscillations and resumption of meiosis. Theriogenology 71:543-552.
  3. Hirabayashi M, Kato M, Kitada K, Ohonami, N, Hirao M, Hochi S (2009) Activation regimens for full-term development of rabbit oocytes injected with round spermatids. Mol Reprod Dev 76:573-579.
  4. Uchimura A, Hidaka Y, Hirabayashi T, Hirabayashi M , Yagi T (2009) DNA polymerase δ is required for early mammalian embryogenesis. PLoS ONE 4:e4184.
  5. Abdalla H, Shimada M, Hirabayashi M, Hochi S (2009) A combined treatment of ionomycin with ethanol improves blastocyst development of bovine oocytes harvested from stored ovaries and microinjected with spermatozoa. Theriogenology 72:453-460.
  6. Abdalla H, Hirabayashi M, Hochi S (2009) Demethylation dynamics of the paternal genome in pronuclear-stage bovine zygotes produced by in vitro fertilization and ooplasmic injection of freeze-thawed or freeze-dried spermatozoa. J Reprod Dev 55:433-439.
  7. Wang Y, Kakizaki T, Sakagami H, Saito K, Ebihara S, Kato M, Hirabayashi M, Saito Y, Furuya N, Yanagawa Y (2009) Fluorescent labeling of both GABAergic and glycinergic neurons in vesicular GABA transporter (VGAT)-venus transgenic mouse. Neuroscience 164:1031-1043.
  8. Yoshimi K, Tanaka T, Takizawa A, Kato M, Hirabayashi M, Mashimo T, Serikawa T, Kuramoto T (2009) Enhanced colitis-associated carcinogenesis in a novel Apc mutant rat. Cancer Sci 100:2022-2027.
  9. Noguchi Y, Hirabayashi T, Katori S, Kawamura Y, Sanbo M, Hirabayashi M, Kiyonari H, Nakao K, Uchimura A, Yagi T (2009) Total expression and dual gene-regulatory mechanisms maintained in deletions and duplications of the Protocadherin-alpha cluster. J Biol Chem 284:32002-32014.
  10. Suzuki A, Ammann P, Nishiwaki-Yasuda K, Sekiguchi S, Shogo A, Nagao S, Kaneko R, Hirabayashi M, Oiso Y, Mitsuyasu I, Caverzasio J (2009) Effects of transgenic Pit-1 overexpression on calcium phosphate and bone metabolism. J Bone Miner Metab (in press).
  11. Yoshizawa Y, Kato M, Hirabayashi M, Hochi S (2009) Impaired active demethylation of paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection. Mol Reprod Dev (in press).
  12. Hirabayashi M, Kato M, Kobayashi T, Sanb M, Yagi T, Hochi S, Nakauchi M (2009) Establishment of rat embryonic stem cell lines that can participate into germline chimerae at high efficiency. Mol Reprod Dev (in press).
D. 研究関係著作
  1. Hirabayashi M, Hochi S (2009) Chapter-9. Generation of transgenic rats by ooplasmic injection of sperm cells exposed to exogenous DNA. “Rat genomics: Methods and Protocols” (Eds. Anegon I), Humana Press, Totowa (in press).

7.2 行動様式解析室

A. 英文原著
  1. Tanaka H, Ma J, Tanaka K, Takao K, Komada M, Tanda, K, Suzukki A, Ishibashi T, Baba H, Isa T, Shigemoto R, Ono K, Miyakawa T, Ikenaka K (2009) Mice with altered myelin proteolipid protein gene expression display cognitive deficits accompanied by abnormal neuron-glia interactions and decreased conduction velocities. J Neurosci 29:8363-8371. 【重複あり】
  2. Kaidanovich-Beilin O, Lipina TV, Takao K, Eede M, Hattori S, Lalibert C, Khan M, Okamoto K, Chambers JW, Fletcher PJ, MacAulay K, Doble BW, Henkelman M, Miyakawa T, Roder J, Woodgett JR (2009) Abnormalities in Brain Structure and Behavior in GSK-3α Mutant Mice. Molecular Brain 2:35.
D. 研究関係著作
  1. 服部聡子, 萩原英雄, 高雄啓三, 宮川剛 (2009) マウスでどこまで精神疾患がわかるか. 精神科 15:144-148.
  2. 駒田到和, 高雄啓三, 松尾直毅, 宮川剛 (2009) 第2項 試験法と結果の評価. “安全性薬理試験マニュアル” LIFE-SCIENCE INFORMATION CNTER, pp 54-63.