論文リスト
2019
Katada Y, Kobayashi K, Tsubota K, Kurihara T (2019)
Evaluation of AAV-DJ vector for retinal gene therapy. PeerJ 7:e6317.
Okada Y, Sumioka T, Ichikawa K, Sano H, Nambu A, Kobayashi
K, Uchida K, Suzuki Y, Tominaga M, Reinach PS, Hirai SI, Jester JV,
Miyajima M, Shirai K, Iwanishi H, Kao WW, Liu CY, Saika S (2019)
Sensory nerve supports epithelial stem cell function in healing of
corneal epithelium in mice: the role of trigeminal nerve transient
receptor potential vanilloid 4. Lab Invest 99:210-230.
Kinoshita M, Kato R, Isa K, Kobayashi K, Kobayashi K, Onoe
H, Isa T (2019) Dissecting the circuit for blindsight to reveal the
critical role of pulvinar and superior colliculus. Nat Commun 10:135.
Nomura K, Hiyama TY, Sakuta H, Matsuda T, Lin CH,
Kobayashi K, Kobayashi K, Kuwaki T, Takahashi K, Matsui S, Noda M
(2019) [Na+] increases in body fluids sensed by central Nax induce
sympathetically mediated blood pressure elevations via H+-dependent
activation of ASIC1a. Neuron 101:60-75.
Kato S, Sugawara M, Kobayashi K, Kimura K, Inoue KI,
Takada M, Kobayashi K (2019) Enhancement of the transduction
efficiency of a lentiviral vector for neuron-specific retrograde gene
delivery through the point mutation of fusion glycoprotein type E. J
Neurosci Methods 311:147-155.
Okubo Y, Kanemaru K, Suzuki J, Kobayashi K, Hirose K, Iino
M (2019) Inositol 1,4,5-trisphosphate receptor type 2-independent Ca2+
release from the endoplasmic reticulum in astrocytes. Glia 67:113-124.
2018
Kobayashi K, Kato S, Kobayashi K (2018) Genetic
manipulation of specific neural circuits by use of a viral vector
system. J Neural Transm (Vienna) 125:67-75.
Terada SI, Kobayashi K, Ohkura M, Nakai J, Matsuzaki M
(2018) Super-wide-field two-photon imaging with a micro-optical device
moving in post-objective space. Nat Commun
9:3550.
Kunisawa K, Shimizu T, Kushima I, Aleksic B, Mori D,
Osanai Y, Kobayashi K, Taylor AM, Bhat MA, Hayashi A, Baba H, Ozaki N,
Ikenaka K (2018) Dysregulation of schizophrenia-related aquaporin 3
through disruption of paranode influences neuronal viability. J
Neurochem 147:395-408.
Osanai Y, Shimizu T, Mori T, Hatanaka N, Kimori Y,
Kobayashi K, Koyama S, Yoshimura Y, Nambu A, Ikenaka K (2018) Length
of myelin internodes of individual oligodendrocytes is controlled by
microenvironment influenced by normal and input-deprived axonal
activities in sensory deprived mouse models. Glia
66:2514-2525.
Yoshida E, Terada S, Tanaka TH, Kobayashi K, Ohkura M,
Nakai J, Matsuzaki M (2018) In vivo wide-field calcium imaging of
mouse thalamocortical synapses with an 8K ultra-high-definition
camera. Sci Rep
8:8324.
Ren Q, Ma M, Yang J, Nonaka R, Yamaguchi
A, Ishikawa KI, Kobayashi
K, Murayama S, Hwang SH, Saiki S, Akamatsu W, Hattori N,
Hammock BD, Hashimoto K (2018) Soluble epoxide hydrolase plays a key
role in the pathogenesis of Parkinson's disease.
Proc Natl Acad Sci U S A 115:5815-5823.
Nakano Y, Karube F, Hirai Y,
Kobayashi K, Hioki H, Okamoto S, Kameda H, Fujiyama F (2018)
Parvalbumin-producing striatal interneurons receive excitatory inputs
onto proximal dendrites from the motor thalamus in male mice.
J Neurosci Res
96:1186-1207.
Okamoto S, Sato T, Tateyama M, Kageyama
H, Maejima Y, Nakata M, Hirako S, Matsuo T, Kyaw S, Shiuchi T, Toda C,
Sedbazar U, Saito K, Asgar NF, Zhang B, Yokota S, Kobayashi
K, Foufelle F, Ferré P, Nakazato M, Masuzaki H, Shioda S, Yada
T, Kahn BB, Minokoshi Y (2018) Activation of AMPK-regulated CRH
neurons in the PVH is sufficient and necessary to induce dietary
preference for carbohydrate over fat. Cell Rep
22:706-721.
2017
Kobayashi K, Inoue KI,
Tanabe S, Kato S, Takada M, Kobayashi K (2017) Pseudotyped lentiviral
vectors for retrograde gene delivery into target brain regions. Front
Neuroanat 11:65.
Morishima M, Kobayashi K,
Kato S, Kobayashi K, Kawaguchi Y (2017) Segregated
excitatory-inhibitory recurrent subnetworks in layer 5 of the rat
frontal cortex. Cereb Cortex 27:
5846-5857.
Tsutsui-Kimura I, Natsubori
A, Mori M, Kobayashi K, Drew MR, de Kerchove d’Exaerde A, Mimura M,
Tanaka KF (2017) Distinct roles of ventromedial versus ventrolateral
striatal medium spiny neurons in reward-oriented behavior. Curr Biol
27:3042–3048.
Kondo M, Kobayashi K, Ohkura
M, Nakai J, Matsuzaki M (2017) Two-photon calcium imaging of the
medial prefrontal cortex and hippocampus without cortical invasion.
Elife 6:e26839.
Shintani T, Higashi S,
Suzuki R, Takeuchi Y, Ikaga R, Yamazaki T, Kobayashi K, Noda M (2017)
PTPRJ inhibits leptin signaling, and induction of PTPRJ in the
hypothalamus is a cause of the development of leptin resistance. Sci
Rep 7:11627.
Coutinho EA, Okamoto S,
Ishikawa AW, Yokota S, Wada N, Hirabayashi T, Saito K, Sato T, Takagi
K, Wang CC, Kobayashi K, Ogawa Y, Shioda S, Yoshimura Y, Minokoshi Y
(2017) Activation of SF1 neurons in the ventromedial hypothalamus by
DREADD technology increases insulin sensitivity in peripheral tissues.
Diabetes 66:2372-2386.
Oh YM, Karube F, Takahashi
S, Kobayashi K, Takada M, Uchigashima M, Watanabe M, Nishizawa K,
Kobayashi K, Fujiyama F (2017) Using a novel PV-Cre rat model to
characterize pallidonigral cells and their terminations. Brain Struct
Funct 222:2359-2378.
Matsuda T, Hiyama TY,
Niimura F, Matsusaka T, Fukamizu A, Kobayashi K, Kobayashi K, Noda M
(2017) Distinct neural mechanisms for the control of thirst and salt
appetite in the subfornical organ. Nat Neurosci 20:230-241.
Tohyama T, Kinoshita M,
Kobayashi K, Isa K, Watanabe D, Kobayashi K, Liu M, Isa T (2017)
Contribution of propriospinal neurons to recovery of hand dexterity
after corticospinal tract lesions in monkeys. Proc Natl Acad Sci U S A
114:604-609.
Taruno A, Kashio M, Sun H,
Kobayashi K, Sano H, Nambu A, Marunaka Y (2017) Adeno-associated
virus-mediated gene transfer into taste cells in vivo. Chem Senses
42:69–78.
Osanai Y, Shimizu T, Mori T,
Yoshimura Y, Hatanaka N, Nambu A, Kimori Y, Koyama S, Kobayashi K,
Ikenaka K (2017) Rabies virus-mediated oligodendrocyte labeling
reveals a single oligodendrocyte myelinates axons from distinct brain
regions. Glia 65:93-105.
2016
Kobayashi K, Sano H, Kato S,
Kuroda K, Nakamuta S, Isa T, Nambu A, Kaibuchi K, Kobayashi K (2016)
Survival of corticostriatal neurons by Rho/Rho-kinase signaling
pathway. Neurosci Lett 630:45-52.
Kobayashi K, Kato S, Inoue
K, Takada M, Kobayashi K (2016) Altering entry site preference of
lentiviral vectors into neuronal cells by pseudotyping with envelope
glycoproteins. Methods Mol Biol 1382:175-186.
Sugaya Y, Yamazaki M,
Uchigashima M, Kobayashi K, Watanabe M, Sakimura K, Kano M (2016)
Crucial roles of the endocannabinoid 2-arachidonoylglycerol in the
suppression of epileptic seizures. Cell Rep 16:1405-1415.
Yokoi N, Fukata Y, Sekiya A,
Murakami T, Kobayashi K, Fukata M (2016) Identification of PSD-95
depalmitoylating enzymes. J Neurosci 36:6431-6444.
Nagai T, Nakamuta S, Kuroda
K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y,
Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura
M, Nishi A, Kobayashi K, Yamada K, Amano M, Kaibuchi K (2016)
Phosphoproteomics of the dopamine pathway enables discovery of Rap1
activation as a reward signal in vivo. Neuron 89:550-565.
Ishida A, Isa K, Umeda T,
Kobayashi K, Kobayashi K, Hida H, Isa T (2016) Causal link between the
cortico-rubral pathway and functional recovery through forced impaired
limb use in rats with stroke. J Neurosci 36:455-467.
2015以前の主な業績
Wahl AS, Omlor W, Rubio JC,
Chen JL, Zheng H, Schröter A, Gullo M, Weinmann O, Kobayashi K,
Helmchen F, Ommer B, Schwab ME (2014) Asynchronous therapy restores
motor control by rewiring of the rat corticospinal tract after stroke.
Science 344:1250-1255.
Kato S, Kobayashi K,
Kobayashi K (2014) Improved transduction efficiency of a lentiviral
vector for neuron-specific retrograde gene transfer by optimizing the
junction of fusion envelope glycoprotein. J Neurosci Methods
227:151-158.
Sooksawate T, Isa K, Matsui
R, Kato S, Kinoshita M, Kobayashi K, Watanabe D, Kobayashi K, Isa T
(2013) Viral vector-mediated selective and reversible blockade of the
pathway for visual orienting in mice. Front Neural Circuits 7:162.
Hirano M, Kato S, Kobayashi
K, Okada T, Yaginuma H, Kobayashi K (2013) Highly efficient retrograde
gene transfer into motor neurons by a lentiviral vector pseudotyped
with fusion glycoprotein. PLoS One 8:e75896.
Kato S, Kuramochi M,
Takasumi K, Kobayashi K, Inoue K, Takahara D, Hitoshi S, Ikenaka K,
Shimada T, Takada M, Kobayashi K (2011) Neuron-specific gene transfer
through retrograde transport of lentiviral vector pseudotyped with a
novel type of fusion envelope glycoprotein. Hum Gene Ther
22:1511-1523.
Kobayashi K, Masuda T,
Takahashi M, Miyazaki J, Nakagawa M, Uchigashima M, Watanabe M,
Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K (2011) Rho/Rho-kinase
signaling pathway controls axon patterning of a specified subset of
cranial motor neurons. Eur J Neurosci 33:612-621.
Kato S, Kobayashi K, Inoue
K, Kuramochi M, Okada T, Yaginuma H, Morimoto K, Shimada T, Takada M,
Kobayashi K (2011) A lentiviral strategy for highly efficient
retrograde gene transfer by pseudotyping with fusion envelope
glycoprotein. Hum Gene Ther 22:197-206.
Kato S, Inoue K, Kobayashi
K, Yasoshima Y, Miyachi S, Inoue S, Hanawa H, Shimada T, Takada M,
Kobayashi K (2007) Efficient gene transfer via retrograde transport in
rodent and primate brains using a human immunodeficiency virus type
1-based vector pseudotyped with rabies virus glycoprotein. Hum Gene
Ther 18:1141-1151.
Kobayashi K, Takahashi M,
Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K,
Kobayashi K (2004) Survival of developing motor neurons mediated by
Rho GTPase signaling pathway through Rho-kinase. J Neurosci
24:3480-3488.
Matsushita N, Kobayashi K,
Miyazaki J, Kobayashi K (2004) Fate of transient catecholaminergic
cell types revealed by site-specific recombination in transgenic mice.
J Neurosci Res 78:7-15.
Kobayashi K, Kuroda S,
Fukata M, Nakamura T, Nagase T, Nomura N, Matsuura Y, Yoshida-Kubomura
N, Iwamatsu A, Kaibuchi K (1998) p140Sra-1 (specifically
Rac1-associated protein) is a novel specific target for Rac1 small
GTPase. J Biol Chem 273:291-295.