| Our main interest lies in elucidation of the mechanism of transduction
and integration of neural information in the nervous system. More specifically,
we are trying to understand the basic properties of neural information
processing between neurons or among a group of neurons constituting a local
network. We are also interested in the pathophysiological mechanism how
a single gene mutation leads to a symptom (such as ataxia, epilepsy and
learning and memory deficits), particularly in Ca2+ channel mutant and Ca2+/calmodulin-dependent protein kinase IIα mutant mice. Additionally, we
have recently started to make a computational approach, incorporating computer-based
neurons into brain slice measurements (dynamic clamp), together with computational
simulation of network functions. |
26.Mar.2013
