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Publication list 2018     

Original papers


Other publications


Publication list 2017     

Original papers

  1. Erami E, Azhdari-Zarmehri H, Imoto K, Furue H (2017) Characterization of Nociceptive Behaviors Induced by Formalin in the Glabrous and Hairy Skin of Rats.Basic Clin Neurosci. 2017 Jan;8(1):37-42. doi: 10.15412/J.BCN.03080105. [PubMed]

  2. Takayama Y, Furue H, Tominaga M (2017) 4-isopropylcyclohexanol has potential analgesic effects through the inhibition of anoctamin 1, TRPV1 and TRPA1 channel activities. Sci Rep. 2017 Feb 22;7:43132. doi: 10.1038/srep43132.[PubMed]

  3. Jang IJ, Davies AJ, Akimoto N, Back SK, Lee PR, Na HS, Furue H, Jung SJ, Kim YH, Oh SB (2017) Acute inflammation reveals GABAA receptor-mediated nociception in mouse dorsal root ganglion neurons via PGE2 receptor 4 signaling.Physiol Rep.2017 Apr;5(8). pii: e13178. doi: 10.14814/phy2.13178.[PubMed]

  4. Koga K, Kanehisa K, Kohro Y, Shiratori-Hayashi M, Tozaki-Saitoh H, Inoue K, Furue H, Tsuda M (2017) Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours.Sci Rep. 2017 Jul 5;7(1):4739. doi: 10.1038/s41598-017-04972-3.[PubMed]

  5. Cormelia Koeberle S, Tanaka S, Kuriu T, Iwasaki H, Koeberle A, Schulz A, Helbing DL, Yamagata Y, Morrison H, Okabe S (2017) Developmental stage-dependent regulation of spine formation by calcium-calmodulin-dependent protein kinase IIα and Rap1. Sci Rep. 2017 Oct 17;7(1):13409. doi: 10.1038/s41598-017-13728-y. [PubMed] [Scientific Reports]

  6. Vuong PM, Nguyen HT, Katano T, Matsumura S, Saito A, Yamada A, Furue H, Ito S (2017) Impaired peripheral nerve regeneration in type-2 diabetic mouse model.Eur J Neurosci. 2017 Nov 9. doi: 10.1111/ejn.13771.[PubMed]

  7. Nakamori H, Naitou K, Horii Y, Shimaoka H, Horii K, Sakai H, Yamada A, Furue H, Shiina T, Shimizu Y(2017)Medullary raphe nuclei activate the lumbosacral defecation center through the descending serotonergic pathway to regulate colorectal motility in rats.Am J Physiol Gastrointest Liver Physiol. 2017 Nov 22:ajpgi.00317.2017. doi: 10.1152/ajpgi.00317.2017. [PubMed]

  8. Kawatani M, Akimoto N, Yamada A, Furue H, Kawatani M (2017) Noradrenergic effects in rat sacral autonomic nucleus using in vitro slice patch-clamp recordings.Biomed Res. 2017;38(6):359-369. doi: 10.2220/biomedres.38.359.[PubMed]

Other publications

  1. Yoshimura M, Furue H (2017) In vivo electrophysiological analysis of pain mechanisms using whole animals, Pain. 2017 Feb 24. doi: 10.1097/j.pain.0000000000000844.[PubMed]

  2. 御領憲治、古江秀昌、脳幹における痛みの抑制と慢性疼痛発現の機構、医学のあゆみ 260(2), 144-148, 2017-01-14 医歯薬出版  

  3. 歌 大介、井本 敬二、古江 秀昌(2017)ラット脊髄後角膠様質細胞への侵害受容シナプス伝達に対する TRPA1 チャネル作動薬の応答解析 ─In vitro および in vivo パッチクランプ解析を用いて─、PAIN RESEARCH Vol.32,170-190

Publication list 2016     

Original papers

  1. Naitou K, Nakamori H, Shiina T, Ikeda A, Nozue Y, Sano Y, Yokoyama T, Yamamoto Y, Yamada A, Akimoto N, Furue H, Shimizu Y (2016) Stimulation of dopamine D2-like receptors in the lumbosacral defecation centre causes propulsive colorectal contractions in rats.J Physiol. 2016 Mar 21. doi: 10.1113/JP272073.[PubMed]

  2. Kurabe M, Furue H, Kohno T (2016) Intravenous administration of lidocaine directly acts on spinal dorsal horn and produces analgesic effect: An in vivo patch-clamp analysis. Sci Rep. 2016 May 18;6:26253. doi: 10.1038/srep26253.[PubMed]

  3. Kozuka Y, Kawamata M, Furue H, Ishida T, Tanaka S, Namiki A, Yamakage M (2016) Changes in synaptic transmission of substantia gelatinosa neurons after spinal cord hemisection revealed by analysis using in vivo patch-clamp recording. Mol Pain 12: 1-14. doi: 10.1177/1744806916665827.[PubMed]

  4. Katano T, Fukuda M, Furue H, Yamazaki M, Abe M, Watanabe M, Nishida K, Yao I, Yamada A, Hata Y, Okumura N,Nakazawa T, Yamamoto T, Sakimura K, Takao T, Ito S (2016) Involvement of brain-enriched guanylate kinase-associated protein (BEGAIN) in chronic pain after peripheral nerve injury. eNeuro Oct 2016,ENEURO.0110-16.2016 .doi: 10.1523/ENEURO.0110-16.2016[PubMed]

  5. Choi S, Yamada A, Kim W, Kim SK, Furue H Noradrenergic inhibition of spinal hyperexcitation elicited by cutaneous cold stimuli in rats with oxaliplatin-induced allodynia: electrophysiological and behavioral assessments.J Physiol Sci (in press) 2016 Nov 28.doi: 10.1007/s12576-016-0505-9[PubMed]

Other publications

  1. Satake S, Inoue T, Imoto K (2016) Synaptic multivesicular release in the cerebellar cortex: its mechanism and role in neural encoding and processing. Cerebellum 2016 Apr;15(2):201-7. doi: 10.1007/s12311-015-0677-5.[PubMed]

Publication list 2015     

Original papers


  1. Nakao A, Miki T, Shimono K, Oka H, Numata T, Kiyonaka S, Matsushita K, Ogura H, Niidome T, Noebels JL, Wakamori M, Imoto K, Mori Y (2015) Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering. Pflügers Archiv 467:737-752. [PubMed]

  2. Mori Y, Tomonaga D, Kalashnikova A, Furuya F, Akimoto N, Ifuku M, Okuno Y, Beppu K, Fujita K, Katafuchi T, Shimura H, Churilov LP, Noda M (2015) Effects of 3,3',5-triiodothyronine on microglial functions.Glia. 2015 May;63(5):906-20. doi: 10.1002/glia.22792.[PubMed]

  3. Yokoi N, Fukata Y, Kase D, Miyazaki T, Jaegle M, Ohkawa T, Takahashi N, Iwanari H, Mochizuki Y, Hamakubo T, Imoto K, Meijer D, Watanabe M, Fukata M (2015) Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy. Nat Med 21:19-26. [PubMed]

  4. Takayama Y, Uta D, Furue H, Tominaga M (2015) Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons. Proc Natl Acad Sci USA 112:5213-5218. [PubMed]

  5. Kase D, Uta D, Ishihara H, Imoto K (2015) Inhibitory synaptic transmission from the substantia nigra pars reticulata to the ventral medial thalamus in mice. Neurosci Res 97:26-35. [PubMed]

  6. Yamagata Y, Nairn AC (2015) Contrasting features of ERK1/2 activity and synapsin I phosphorylation at the ERK1/2-dependent site in the rat brain in status epilepticus induced by kainic acid in vivo. Brain Res 1625:314-323. [PubMed][Brain Research][生理研HP][NIPS HP]

  7. Tonomura S, Ebara S, Bagdasarian K, Uta D, Ahissar E, Meir I, Lampl I, Kuroda D, Furuta T, Furue H, Kumamoto K (2015) Structure-function correlations of rat trigeminal primary neurons: Emphasis on club-like endings, a vibrissal mechanoreceptor.Proc Jpn Acad Ser B Phys Biol Sci. 2015;91(10):560-76. doi: 10.2183/pjab.91.560. [PubMed]

Other publications

  1. 山田彬博,古江秀昌(2015)神経障害性痛で生じるClイオン濃度勾配は,GABAで痛みが生じるほど大きな変化なのですか?.LiSA Vol.22 No.2 2015.130-131

Publication list 2014     

Original papers

  1. Takeuchi Y, Asano H, Katayama Y, Muragaki Y, Imoto K, Miyata M (2014) Large-scale somatotopic refinement via functional synapse elimination in the sensory thalamus of developing mice. J Neurosci 34:1258-1270. [PubMed]

  2. Satake S, Imoto K(2014) Cav2.1 channels control multivesicular release by relying on their distance from exocytotic Ca2+ sensors at rat cerebellar granule cells. J Neurosci 34:1462-1474. [PubMed]

  3. Funai Y, Pickering AE, Uta D, Nishikawa K, Mori T, Asada A, Imoto K, Furue H (2014) Systemic dexmedetomidine augments inhibitory synaptic transmission in the superficial dorsal horn through activation of descending noradrenergic control: an in vivo patch-clamp analysis of analgesic mechanisms. Pain 155:617-628. [PubMed]

  4. Ohtani Y, Miyata M, Hashimoto K, Tabata T, Kishimoto Y, Fukaya M, Kase D, Kassai H, Nakao K, Hirata T, Watanabe M, Kano M, Aiba A (2014) The synaptic targeting of mGluR1 by its carboxyl-terminal domain is crucial for cerebellar function. J Neurosci 34:2702-2712. [PubMed]

  5. Hickey L, Li Y, Fyson SJ, Watson TC, Perrins R, Hewinson J, Teschemacher AG, Furue H, Lumb BM, Pickering AE (2014) Optoactivation of locus ceruleus neurons evokes bidirectional changes in thermal nociception in rats. J Neurosci 34:4148-4160. [PubMed]

  6. Ohkawa T, Satake S, Yokoi N, Miyazaki Y, Ohshita T, Sobue G, Takashima H, Watanabe O, Fukata Y, Fukata M (2014) Identification and characterization of GABAA receptor autoantibodies in autoimmune encephalitis. J Neurosci 34:8151-8163. [PubMed]

  7. Kon N, Yoshikawa T, Honma S, Yamagata Y, Yoshitane H, Shimizu K, Sugiyama Y, Hara C, Kameshita I, Honma K, Fukada Y (2014) CaMKII is essential for the cellular clock and coupling between morning and evening behavioral rhythms. Genes Dev 28:1101-1110. [PubMed]

  8. Nishida K, Matsumura S, Taniguchi W, Uta D, Furue H, Ito S (2014) Three-dimensional distribution of sensory stimulation-evoked neuronal activity of spinal dorsal horn neurons analyzed by in vivo calcium imaging. PLoS One 9:e103321. [PubMed]

Other publications

  1. 古江秀昌(2014)下行性制御機構:セロトニン系、ノルアドレナリン系.日本医師会雑誌143巻特別号(1)痛みのマネジメントupdate, p42-3.

  2. 山肩葉子(2014)シナプシン. 脳科学辞典 DOI:10.14931/bsd.5428

Publication list 2013     

Original papers

  1. Yamagata Y, Kaneko K, Kase D, Ishihara H, Nairn AC, Obata K, Imoto K (2013) Regulation of ERK1/2 mitogen-activated protein kinase by NMDA-receptor-induced seizure activity in cortical slices. Brain Res 1507:1-10. [PubMed][Brain Research][生理研HP][NIPS HP]

  2. Ikeda K, Satake S, Onaka T, Sugimoto H, Takeda N, Imoto K, Kawakami K (2013)Enhanced inhibitory neurotransmission in the cerebellar cortex of Atp1a3-deficient heterozygous mice.J Physiol591(Pt 13):3433-49.[PubMed]

  3. Akimoto N, Honda K, Uta D, Beppu K, Ushijima Y, Matsuzaki Y, Nakashima S, Kido MA, Imoto K, Takano Y, Noda M (2013) CCL-1 in the spinal cord contributes to neuropathic pain induced by nerve injury. Cell Death Dis 4:e679.[PubMed]

Other publications

  1. 宍戸恵美子 「あしたばケースレポート」(公益市民団体あしたば 2013年予定)

  2. 宍戸恵美子 「話す」(行動科学ブックレット 2013年予定)

  3. Konishi S, Satake S (2013) Physiological interactions between neurons and glia: roles of transporters in the control of intersynaptic crosstalk. In Glial Cells: Embryonic Development, Types/Functions and Role in Disease. (Eds. Kaur C, Ling EA) New York: Nova Science Publishers, 177-192.

Publication list 2012 

Original papers

  1. Kase D, Inoue T, Imoto K (2012) Roles of the subthalamic nucleus and subthalamic HCN channels in absence seizures. J Neurophysiol 107:393-406. [PubMed]

  2. Sugiyama D, Hur SW, Pickering AE, Kase D, Kim SJ, Kawamata M, Imoto K, Furue H(2012) In vivo patch-clamp recording from locus coeruleus neurones in the rat brainstem. J Physiol 590:2225-2231. [PubMed]

  3. Takeuchi Y, Yamasaki M, Nagumo Y, Imoto K, Watanabe M, Miyata M (2012) Rewiring of afferent fibers in the somatosensory thalamus of mice caused by peripheral sensory nerve transection. J Neurosci 32:6917-6930. [PubMed]

  4. Satake S, Inoue T, Imoto K (2012) Paired-pulse facilitation of multivesicular release and intersynaptic spillover of glutamate at rat cerebellar granule cell-interneurone synapses. J Physiol 590:5653-5675. [PubMed]

  5. Saito Y, Inoue T, Zhu G, Kimura N, Okada M, Nishimura M,Kimura N, Murayama S, Kaneko S, Shigemoto R, Imoto K,Suzuki T (2012)Hyperpolarization-activated cyclic nucleotide gated channels:a potential molecular link between epileptic seizures and Aβgeneration in Alzheimer’s disease.Mol Neurodegener 7:50.[PubMed]

  6. Xie DJ, Uta D, Feng PY, Wakita M, Shin MC, Furue H, Yoshimura M (2012) Identification of 5-HT receptor subtypes enhancing inhibitory transmission in the rat spinal dorsal horn in vitro. Molecular pain 8:58.[PubMed]

Other publications

  1. 宍戸恵美子(2012)自閉症スペクトラムとシナプス蛋白質のアンバランス.BRAIN and NERVE 64(1):65-70
      
  2. 古江秀昌,加藤剛,馬場洋(2012)ノルアドレナリン.Bone Joint Nerve

  3. Kase D, Imoto K (2012) The role of HCN channels on membrane excitability in the nervous system. J Signal Transduct 2012:619747.[PubMed]

  4. 古江秀昌,井本敬二,杉山大介,川真田樹人,舟井優介,西川精宣 (2012)下行性ノルアドレナリン痛覚抑制機構とその活動制御.麻酔61増刊:S30-40.

  5. Furue H (2012) In Vivo Blind Patch-Clamp Recording Technique. In: Patch Clamp Techniques (Okada Y, ed), pp 171-182. Totowa: Springer.

  6. 宍戸恵美子、井本敬二(2012)幼児の早期介入はどうして有効なのか?.行動科学 51:37−44.

Publication list 2011

Original papers

  1. Nagumo Y, Takeuchi Y, Imoto K, Miyata M (2011) Synapse- and subtype-speciifc modulaton of synaptic transmission by nicotinic acetylcholine receptor in the ventrobasal thalamus. Neurosci Res,2011 Mar;69(3):203-13. [PubMed]
      
  2. Jingshan Lu, Tayo Katano, Daisuke Uta, Hidemasa Furue, and Seiji Ito(2011)Rapid S-nitrosylation of actin by NO-generating donors and in inflammatory pain model mice.Molecular Pain 2011, 7:101.[PubMed]

Other publications

  1. 伊佐 正,井本敬二,川口泰雄(2011)スライスパッチクランプ法.最新パッチクランプ実験技術法.岡田泰伸 編.吉岡書店:86‐95.

  2. 古江秀昌(2011).In vivoブラインドパッチ法.最新パッチクランプ実験技術法.岡田泰伸 編.吉岡書店:115-120.

  3. 山肩葉子,井本敬二(2011)長期記憶の分子機構.Clinical Neuroscience 29:777-781.

  4. 宍戸恵美子(2011) 「教えて、のばす!発達障害をかかえた子ども」.少年写真新聞社. 平岩幹男(監修)、宍戸恵美子(著)

  5. 宍戸恵美子(2011)自閉症スペクトラムとシナプス蛋白質のアンバランス,Brain and Nerve,医学書院

  6. 宍戸恵美子(2011)自閉症療育をめぐってー自閉症とその療育−.子育て支援ハンドブック.日本小児科連絡協議会

  7. 佐竹伸一郎 (2011) 神経伝達物質の細胞膜型トランスポーター. トランスポートソー ムの世界:膜輸送研究の源流から未来へ.(金井好克、竹島 浩、森 泰生、久保義弘 編)京都廣川書店. 214-225.

  8. 佐竹伸一郎、小西史朗、井本敬二 (2011) ニューロン型グルタミン酸トランスポー ターが制御する異種シナプス間クロストーク. 脳21 14, 320-325.


Publication list 2010

Original papers

  1. Yanagisawa Y, Furue H, Kawamata T, Uta D, Yamamoto J, Furuse S, Katafuchi T, Imoto K, Iwamoto Y and Yoshimura M (2010) Bone cancer induces a unique central sensitization through synaptic changes in a wide area of the spinal cord. Mol Pain 2010, 6:38. [Molecular Pain] [PubMed]
       
  2. Uta D, Furue H, Pickering A.E, Rashid M.H,Mizuguchi-Takase H, Katafuchi T, Imoto K, Yoshimura M (2010) TRPA1-expressing primary afferents synapse with a morphologically identified subclass of substantia gelatinosa neurons in the adult rat spinal cord. Eur J Neurosci 31:1960-1973 [PubMed]
      
  3. Georgiev S.K, Furue H, Baba H, Kohno T (2010) Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons. Molecular Pain 2010, 6:25 [PubMed]
       
  4. Hachisuka J, Furue H, Furue M, and Yoshimura M (2010) Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo. J Neurophysiol 104:271-279 [PubMed]

  5. Grossman AW, Aldridge GM, Lee KJ, Zeman MK, Jun CS, Azam HS, Arii T, Imoto K, Greenough WT, Rhyu IJ (2010) Developmental characteristics of dendritic spines in the dentate gyrus of Fmr1 knockout mice. Brain Res 1355:221-227.[PubMed]

  6. Satake S, Song S-Y, Konishi S, Imoto K (2010) Glutamate transporter EAAT4 in Purkinje cells controls intersynaptic diffusion of climbing fiber transmitter mediating inhibition of GABA release from interneurons. Eur J Neurosci 32:1843-1853. [PubMed]   
     

Other publications

  1. 古江秀昌, 杉山大介 (2010) 生理学の立場から光学異性体の末梢神経(後根神経節細胞)への作用の違い.浅田章, 西川精宣編.レボブピバカインの基礎と臨床.克誠堂出版, 東京,pp51-64
        
  2. 古江秀昌,歌大介 (2010) 局所麻酔薬光学異性体の痛覚伝達選択的な遮断効果 ―基礎生理学的な検討―.日本臨床麻酔学会誌 30:535-544.
       

Publication list 2009

Original papers

  1. Miyata M, Imoto K (2009) Contrary roles of kainate receptors in transmitter release at corticothalamic synapses onto thalamic relay and reticular neurons. J Physiol 587:999-1012. [PubMed]

  2. Yamagata Y, Kobayashi S, Umeda T, Inoue A, Sakagami H, Fukaya M, Watanabe M, Hatanaka N, Totsuka M, Yagi T, Obata K, Imoto K, Yanagawa Y, Manabe T, Okabe S (2009) Kinase-dead knock-in mouse reveals an essential role of kinase activity of Ca2+/calmodulin-dependent protein kinase IIalpha in dendritic spine enlargement, long-term potentiation, and learning. J Neurosci 29:7607-18. [PubMed][生理研HP][NIPS HP]

  3. Itoh H, Sakaguchi T, Ding WG, Watanabe E, Watanabe I, Nishio Y, Makiyama T, Ohno S, Akao M, Higashi Y, Zenda N, Kubota T, Mori C, Okajima K, Haruna T, Miyamoto A, Kawamura M, Ishida K, Nagaoka I, Oka Y, Nakazawa Y, Yao T, Jo H, Sugimoto Y, Ashihara T, Hayashi H, Ito M, Imoto K, Matsuura H, Horie M (2009) Latent genetic backgrounds and molecular pathogenesis in drug-induced long-QT syndrome. Circ Arrhythm Electrophysiol 2:511-523.  


Other publications

  1. 井本敬二 (2009) ストア作動性チャネル. Clinical Neuroscience vol27;480.

  2. Wakamori M, Imoto K (2009) Voltage-gated calcium channels. in "Handbook of Neurochemistry and Molecular Neurobiology, 3rd ed" (Eds Lajtha A, Mikoshiba K) Springer, New York, USA, pp 543-558


Publication list 2008

Original papers

  1. Inoue T, Strowbridge BW (2008) Transient activity induces a long-lastingig increase in the excitability of olfactory bulb interneurons. J Neurophysiol 99:187-199. [PubMed]

Other publications

  1. 井上 剛, 井本 敬二  (2008) ダイナミッククランプ法を用いて神経回路網を操作する. 日本神経回路学会誌 15:117-125.

Publication list 2007

Original papers

  1. Itoh H, Tsuji K, Sakaguchi T, Nagaoka I, Oka Y, Nakazawa Y, Yao T, Jo H, Ashihara T, Ito M, Horie M, Imoto K (2007) A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome. Int J Cardiol 121:239-248. [PubMed]

  2. Lee KJ, Jung JG, Arii T, Imoto K, Rhyu IJ (2007) Morphological changes in dendritic spines of Purkinje cells associated with motor learning. Neurobiol Learn Mem 88:445-450. [PubMed]

Other publications

  1. Miyata M (2007) Distinct properties of corticothalamic and primary sensory synapses to thalamic neurons. Neurosci Res 59:377-382. [PubMed]

  2. 山肩 葉子 (2007) 脳内におけるリン酸化シグナル伝達-Ca2+/カルモジュリン依存性プロテインキナ-ゼ IIの新たな役割. Clinical Neuroscience 25: 260-261.

Publication list 2006

Original papers

  1. Satake S, Song SY, Cao Q, Satoh H, Rusakov DA, Yanagawa Y, Ling EA, Imoto K, Konishi S (2006) Characterization of AMPA receptors targeted by the climbing fiber transmitter mediating presynaptic inhibition of GABAergic transmission at cerebellar interneuron-Purkinje cell synapses. J Neurosci 26:2278-2289. [PubMed]

  2. Sasaki S, Huda K, Inoue T, Miyata M, Imoto K (2006) Impaired feedforward inhibition of the thalamocortical projection in epileptic Ca2+ channel mutant mice, tottering. J Neurosci 26:3056-3065 . [PubMed]

  3. Tallini YN, Ohkura M, Choi BR, Ji G, Imoto K, Doran R, Lee J, Plan P, Wilson J, Xin HB, Sanbe A, Gulick J, Mathai J, Robbins J, Salama G, Nakai J, Kotlikoff MI (2006) Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2. Proc Natl Acad Sci USA 103:4753-4758. [PubMed]

  4. Itoh H, Horie M, Ito M, Imoto K (2006) Arrhythmogenesis in the short-QT syndrome associated with combined HERG channel gating defects: a simulation study. Circulation J 70:502-508. [PubMed] [J-Stage]

  5. Yamagata Y, Imoto K, Obata K (2006) A mechanism for the inactivation of Ca2+/calmodulin-dependent proteinkinase II during prolonged seizure activity and its consequence after the recovery from seizure activity in rats in vivo. Neuroscience 14:981-992. [PubMed]

  6. Inoue T, Murakami M, Watanabe S, Inokuma Y, Kirino Y (2006) In vitro odor-aversion conditioning in a terrestrial mollusk. J Neurophysiol 95:3898-3903. [PubMed]

  7. Miyata M, Imoto K (2006) Different composition of glutamate receptors in corticothalamic and lemniscal synaptic responses and their roles in the firing responses of ventrobasal thalamic neurons in juvenile mice. J Physiol 575:161-174. [PubMed]

  8. Inoue T, Imoto K (2006) Feedforward inhibitory connections from multiple thalamic cells to multiple regular-spiking cells in layer 4 of the somatosensory cortex. J Neurophysiol 96:1746-1754. [PubMed]
  9. Kodama T, Itsukaichi-Nishida Y, Fukazawa Y, Wakamori M, Miyata M, Molnar E, Mori Y, Shigemoto R, Imoto K (2006) A CaV2.1 calcium channel mutation rocker reduces the number of postsynaptic AMPA receptors in parallel fiber-Purkinje cell synapses. Eur J Neurosci 24:2993-3007.

Other publications

  1. 宮田麻理子 (2006) 炎症性疼痛と代謝型グルタミン酸受容体.Clinical Neuroscience 24:180-184.

Publication list 2005

Original papers

  1. Kirino Y, Inoue T, Watanabe S (2005) Behavioral Determination of Odor Preference is Coded by the Oscillation Frequency in a Collective Oscillating Network of a Terrestrial Mollusk. Chem Senses Suppl 1:i154-i155.

  2. Kodama T, Imai H, Doi T, Chisaka O, Shichida Y, Fujiyoshi Y (2005) Expression and localization of an exogenous G protein-coupled receptor fused with the rhodopsin C-terminal sequence in the retinal rod cells of knockin mice. Exp Eye Res 80:859-869.[PubMed]

  3. Itoh H, Shimizu M, Mabuchi H, Imoto K (2005) Clinical and electrophysiological characteristics of Brugada syndrome caused by a missense mutation in the S5-pore site of SCN5A. J Cardiovasc Electrophysiol 16:378-383. [PubMed]

  4. Itoh H, Shimizu M, Tanaka S, Mabuchi H, Imoto K (2005) A novel missense mutation in the SCN5A gene associated with Brugada syndrome bidirectionally affecting blocking actions of antiarrhythmic drugs. J Cardiovasc Electrophysiol 16:486-493. [PubMed]

  5. Ohkura M, Matsuzaki M, Kasai H, Imoto K, Nakai J (2005) Genetically encoded bright Ca2+ probe applicable for dynamic Ca2+ imaging of dendritic spines. Anal Chem 77:5861-5869. [PubMed]

Other publications

  1. 伊藤 英樹、井本 敬二 (2005) Na+チャネル異常による不整脈疾患 ―いかに分子異常を病態と結びつけるか―. 生体の科学 56:230-234.
  2. 井本 敬二 (2005) イオンチャネルと神経情報伝達 In "脳・神経科学集中マスター" (真鍋 俊也 編) pp 62-69 羊土社.
  3. 井本 敬二、佐々木 幸恵 (2005) イオンチャネルと神経疾患.日本神経精神薬理学雑誌 25:189-196.

  4. 井本 敬二、伊藤 英樹 (2005) SCN5Aタンパク(SCNA5A). 生体の科学 56:444-445.

  5. 宮田麻理子 (2005) 大脳皮質―視床投射の動的機構 In "ブレインサイエンスレビュー2005"pp 236-250 クバプロ出版.

 

Publication list 2004

Original papers

  1. Inoue T, Inokuma Y, Watanabe S, Kirino Y (2004) In vitro study of odor-evoked behavior in a terrestrial mollusk. J Neurophysiol 91:372-381.[PubMed]

  2. Murakami M, Watanabe S, Inoue T, Kirino Y (2004) Odor-evoked responses in the olfactory center neurons in the terrestrial slug. J Neurobiol 58:369-378. [PubMed]

  3. Satake S, Saitow F, Rusakov D, Konishi S (2004) AMPA receptor-mediated presynaptic inhibition at cerebellar GABAergic synapses: a characterization of molecular mechanisms. Eur J Neurosci 19:2464-2474. [PubMed]

  4. Hartmann J, Blum R, Kovalchuk Y, Adelsberger H, Kuner R, Durand GM, Miyata M, Kano M, Offermanns S, Konnerth A (2004) Distinct roles of Galpha(q) and Galpha11 for Purkinje cell signaling and motor behavior. J Neurosci 24:5119-5130. [PubMed]

  5. Zhang R, Nagata T, Hayashi T, Miyata M, Kawakami Y (2004) Intracerebroventricular injection of trazodone produces 5-HT receptor subtype mediated anti-nociception at the supraspinal and spinal levels. Eur Neuropsychopharmacol 14:419-424. [PubMed]

  6. Yamagata Y, Obata K (2004) Ca2+/calmodulin-dependent protein kinase II is reversibly autophosphorylated, inactivated and made sedimentable by acute neuronal excitation in rats in vivo. J Neurochem 91:745-754. [PubMed]

  7. Matsuyama Z, Yanagisawa NK, Aoki Y, Black JL 3rd, Lennon VA, Mori Y, Imoto K, Inuzuka T (2004) Polyglutamine repeats of spinocerebellar ataxia 6 impair the cell-death-preventing effect of CaV2.1 Ca2+ channel--loss-of-function cellular model of SCA6. Neurobiol Dis 17:198-204. [PubMed]

Other publications

  1. Imoto K (2004) Ion channels, in "Encyclopedia of Endocrine Diseases" (ed. Martini L), Elsevier Academic Press, Amsterdam, Boston.

  2. 井本 敬二 (2004) カルシウムチャネル変異とシナプス伝達の変化.蛋白質核酸酵素 49:405-410.

  3. 宮田 麻理子 (2004) 小脳のシナプス伝達と可塑性 運動学習の分子基盤.Molecular Medicine 41:1102-1108.

  4. 宮田 麻理子 (2004) 炎症性疼痛における視床mGluR1-PLC beta 4カスケードの役割.神経研究の進歩.

  5. 宮田 麻理子 (2004) "大脳皮質‐視床投射の動的機構", in ブレインサイエンスレビュー 2005. クバプロ, 東京

 

Publication list 2003

Original papers

  1. Huda K, Matsunami K (2003) Influence of dopamine on ventrolateral thalamic inputs in cat motor cortex. Brain Res 963:178-189. [PubMed]

  2. Ikeda K, Onaka T, Yamakado M, Nakai J, Ishikawa TO, Taketo MM, Kawakami K (2003) Degeneration of the amygdala/piriform cortex and enhanced fear/anxiety behaviors in sodium pump alpha2 subunit (Atp1a2)-deficient mice. J Neurosci 23:4667-4676. [PubMed]

  3. Mori M, Konno T, Morii T, Nagayama K, Imoto K (2003) Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe. Biochem Biophys Res Comm 307:290-296. [PubMed]

  4. Miyata M, Kashiwadani H, Fukaya M, Hayashi T, Wu D, Suzuki T, Watanabe M, Kawakami Y (2003) Contribution of thalamic phospholipase C beta-4 via the metabotropic glutamate receptor type 1 to inflammatory pain in mice. J Neurosci 23: 8098-8108. [PubMed]

  5. Akiba I, Seki T, Mori M, Iizuka M, Nishimura S, Sasaki S, Imoto K, Barsoumian EL (2003) Stable expression and characterization of human PN1 and PN3 sodiumchannels. Receptors Channels. 9:291-299. [PubMed]

Other publications

  1. Yamagata Y (2003) New aspects of neurotransmitter release and exocytosis: Dynamic and differential regulation of synapsin I phosphorylation by acute neuronal excitation in vivo. J Pharmacol Sci 93:22-29. [PubMed]

Publication list 2002

Original papers

  1. Hara Y, Wakamori M, Ishii M, Maeno E, Nishida M, Yoshida T. Yamada H, Shimizu S, Mori E, Kudoh J, Shimizu N, Kurose H, Okada Y, Imoto K, Mori Y (2002) LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Molecular Cell 9:163-173. [PubMed]

  2. Morii T, Sato S, Hagihara M, Mori Y, Imoto K, Makino K (2002) Structure-based design of a leucine zipper protein with new DNA contacting region. Biochemistry 41:2177-2183. [PubMed]

  3. Morii T, Sugimoto K, Makino K, Otsuka M, Imoto K, Mori Y (2002) A new fluorescent biosensor for inositol trisphosphate. J Am Chem Soc 124:1138-1139. [PubMed]

  4. Matsushita K, Wakamori M, Rhyu I.-J, Arii T, Oda S, Mori Y, Imoto K (2002) Bidirectional alterations in cerebellar synaptic transmission of tottering and rolling Ca2+ channel mutant mice. J Neurosci 22:4388-4398. [PubMed]

  5. Proenza C, O'Brien J, Nakai J, Mukherjee S, Allen PD, Beam KG (2002) Identification of a region of RYR1 that participates in allosteric coupling with the a1S (CaV1.1) II-III loop. J Biol Chem 277: 6530-6535.[PubMed]

  6. Kato K, Wakamori M, Mori Y, Imoto K, Kitamura K (2002) Inhibitory effects of cilnidipine on peripheral and brain N-type Ca2+ channels expressed in BHK cells. Neuropharmacology 42:1099-1108.[PubMed

  7. Protasi F, Paolini C, Nakai J, Beam KG, Franzini-Armstrong C, Allen PD (2002) Multiple regions of RyR1 mediate functional and structural interactions with a1S-DHPR in skeletal muscle. Biophys J 83:3230-3244. [PubMed]

Other publications

  1. Mori Y, Inoue R, Ishii M, Hara Y, Imoto K (2002) Dissecting recetpor-mediated Ca2+ influx pathways:TRP channels and their native counterparts. Jpn J Pharmacol 87:245-252. [PubMed]

  2. Imoto K (2002) Voltage-dependent Na+ channel. in "Encyclopedic Reference of Molecular Pharmacology" (ed. Offermanns S, Rosenthal W), Springer-Verlag,Heidelberg.

  3. 井本 敬二,松下 かおり (2002) 電位依存性Na+チャネル・Ca2+チャネルと神経疾患.医学のあゆみ 201:1128-1132.

  4. 中井淳一,大倉正道 (2002) GFPを用いた蛍光カルシウムプローブG-CaMPの開発.比較生理生化学 19:135-145.

  5. Nakai J, Ohkura M (2002) Probing calcium ions with biosensors. Biotechnology and Genetic Engineering Reviews .
 

Publication list 2001

Original papers

  1. Nakai J, Ohkura M & Imoto K (2001) A high signal-to-noise Ca2+ probe composed of a single green fluorescent protein. Nature Biotechnology 19: 137-141. [PubMed]

  2. Ino M, Yoshinaga T, Wakamori M, Miyamoto N, Takahashi E, Sonoda J, Kagaya T, Oki T, Nagasu T, Nishizawa Y, Tanaka I, Imoto K, Aizawa S, Koch S, Schwartz A, Niidome T, Sawada K, Mori Y (2001) Functional disorder of sympathetic nervous system in mice lacking ?1B subunit (Cav 2.2) of N-type calcium channel. Proc Natl Acad Sci USA 98:5323-5328. [PubMed]

  3. Sugawara T, Tsurubuchi Y, Agarwala KL, Ito M, Fukuma G, Mazaki-Miyazaki E, Nagafuji H, Noda M, Imoto K, Wada K, Mitsudome A, Kaneko S, Montal M, Nagata K, Hirose S, & Yamakawa K (2001) A missense mutation of the Na+ channel alphaII subunit gene Nav1.2 in a patient with febrile and afebrile seizures causes channel dysfunction. Proc Natl Acad Sci USA 98: 6384-6389. [PubMed]

  4. Huda K, Salunga TL & Matsunami K (2001) Dopaminergic inhibition of excitatory inputs onto pyramidal tract neurons in cat motor cortex. Neurosci Lett 307:175-178. [PubMed]

  5. Hatakeyama S, Wakamori M, Ino M, Miyamoto N, Takahashi E, Yoshinaga T, Sawada K, Imoto K, Tanaka I, Yoshizawa T, Nishizawa Y, Mori Y, Niidome T, Shoji S (2001) Differential nociceptive responses in mice lacking the ?1B subunit of N-type Ca2+ channels. NeuroReport 12:2423-2427. [PubMed]



Publication list 2000

Original papers

  1. Bichet D, Cornet V, Geib S, Carlier E, Volsen S, Hoshi T, Mori Y & De Waard M (2000) The I-II loop of Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit. Neuron 25,177-190. [PubMed]

  2. Yamazaki Y, Yagi T, Ozaki T, & Imoto K (2000) In vivo gene transfer to mouse spermatogenic cells using green fluorescent protein as a marker. J Exp Zool 286: 212-218. [PubMed]

  3. Mori M, Konno T, Ozawa T, Murata M, Imoto K, & Nagayama K (2000) Novel interaction of the voltage-dependent sodium channel (VDSC) with calmodulin: does VDSC acquire calmodulin-mediated Ca2+-sensitivity? Biochemistry. 39: 1316-1323. [PubMed]

  4. Shibata R, Nakahira K, Shibasaki K, Wakazono Y, Imoto K, & Ikenaka K (2000) A-Type K+ current mediated by the Kv4 channel regulates the generation of action potential in developing cerebellar granule cells. J Neurosci. 20: 4145-4155. [PubMed]

  5. Iwasa K, Takamori M, Konami K, & Mori Y (2000) Recombinant calcium channel is recognized by Lambert-Eaton myasthenic syndrome antibodies. Neurology 54, 757-759. [PubMed]

  6. Yamada H, Wakamori M, Hara Y, Takahashi Y, Konishi K, Imoto K, & Mori Y (2000) Spontaneous single-channel activity of neuronal TRP5 channel recombinantly expressed in HEK293 cells. Neurosci Lett 285: 111-114. [PubMed]

  7. Mori Y, Wakamori M, Oda Si, Fletcher CF, Sekiguchi N, Mori E, Copeland NG, Jenkins NA, Matsushita K, Matsuyama Z, & Imoto K (2000) Reduced voltage sensitivity of activation of P/Q-type Ca2+ channels is associated with the ataxic mouse mutation rolling nagoya. J Neurosci 20, 5654-62. [PubMed]

  8. Nishimura S, Iizuka M, Akiba I, Wakamori M, Imoto K, & Barsoumian EL (2000) Stable expression of human homomeric and heteromeric AMPA receptor subunits in HEK293 cells. Receptors Channels 7: 139-150. [PubMed]

  9. Iizuka M, Nishimura S, Wakamori M, Akiba I, Imoto K, & Barsoumian EL. (2000) The lethal expression of the GluR2flip/GluR4flip AMPA receptor in HEK293 cells. Eur J Neurosci 12:3900-3908. [PubMed]

Other papers

  1. 古市 貞一、森 泰生 (2000) 電位依存性カルシウムチャネル. Clinical Neuroscience 18: 267-273.

  2. 井本 敬二 (2000) 電位依存性ナトリウムチャネル. Clinical Neuroscience 18: 274-277.

  3. Ertel E, Campbell KP, Harpold MM, Hofmann F, Mori Y, Perez-Reyes E, Schwartz A, Snutch T, Tanabe T, Birnbaumer L, Tsien RW & Catterall WA (2000) Nomenclature of Voltage-Gated Calcium Channels. Neuron 25, 533-535.

  4. 井上隆司、森泰生、伊東祐之  新しい標的分子としてのTRP関連蛋白質:受容体作動性陽イオン チャネルとの分子的相関  蛋白質 核酸 酵素 (4月増刊号:最先端創薬・戦略的アプローチと 先端的医薬品:長尾拓、成宮周、加藤隆一、宮本英七 編)  45, 1038-1046 (2000).

  5. 古市貞一、森泰生  カルシウムチャネル  Clinical Neuroscience (特集 チャネロパチー:岡本幸一 編) 18 (3), 27-33 (中外医学社、2000).

  6. 森泰生、若森実  電位依存性チャネル  脳神経科学イラストレイテッド (in press) (森寿、真鍋俊也、渡辺雅彦、岡野栄之、宮川剛 編、 羊土社、2000).

  7. Imoto K. Structure and function of voltage-dependent Na+ channel. in "Handbook of Experimental Pharmacology", Volume 147, Pharmacology of ionic channel functions: activatiors and inhibitors (ed. Endo M, Kurachi Y, Mishina M), pp. 3-26, Springer-Verlag,Heidelberg, 2000.

Publication list 1999

Original papers

  1. Matsuyama Z, Wakamori M, Mori Y, Kawakami H, Nakamura S & Imoto K (1999) Direct alteration of the P/Q type Ca2+ channel property by polyglutamine expansion in spinocerebellar ataxia 6 (SCA6). J Neuroscience 19 (RC14): 1-5. [PubMed]

  2. Nakai J, Gao L, Xin C, Pasek DA & Meissner G (1999) Evidence for a role of C-terminus in Ca2+ inactivation of skeletal muscle Ca2+ release channel (ryanodine receptor). FEBS Lett 459:154-158. [PubMed]

  3. Aizawa Y, Sugiura Y, Ueno M, Mori Y, Imoto K, Makino K & Morii T (1999) Stability of the dimerization domain effects the cooperative DNA binding of short peptides. Biochemistry 38: 4008-4017. [PubMed]

  4. Boccaccio A, Moran O, Imoto K & Conti F (1999) Tonic and phasic TTX-block of sodium channels with point mutations in the outer pore region. Biophys J 77: 229-40. [PubMed]

  5. Matsuyama Z, Izumi I, Kameyama M, Kawakami H & Nakamura S (1999) The effect of CAT trinucleotide interruptions on the age at onset of spinocerebellar ataxia type 1 (SCA1). J Med Genet 36: 546-548. [PubMed]

  6. Matsuyama Z, Kawakami H, Maruyama H, Harada H, Nakata K, Yamaguchi Y & Nakamura S (1999) Variation in the number of CAG repeats in the Machado-Joseph disease gene (MJD1) in the Japanese population. J Nuerol Sci 166: 71-73. [PubMed]

  7. Walker D, Bichet D, Grieb S, Mori E, Cornet V, Snutch TP, Mori Y & DeWaard M (1999) A new beta-subtype specific interaction in alpha1A subunit controls P/Q-type Ca2+ channel activation. J Biol Chem 274: 12383-12395. [PubMed]

  8. Wakamori M, Mikala G & Mori Y (1999) Auxiliary subunits operate as a molecular switch in determining gating behavior of unitary N-type Ca2+ channel currents. J Physiol 517: 659-672. [PubMed]

  9. Takahashi E, Murata Y, Oki T, Miyamoto N, Mori Y, Takada N, Wanifuchi H, Yagami K, Niidome T, Tanaka I & Katayama K (1999) Isolation and functional characterization of the 5'-upstream region of mouse P/Q-type Ca2+ channel alpha1A subunit gene. Biochem Biophys Res Comm 260: 54-59. [PubMed]

  10. Okada T, Inoue R, Yamazaki K, Maeda A, Kurosaki T, Yamakuni T, Tanaka I, Shimizu S, Ikenaka K, Imoto K, and Mori Y (1999) Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7: Ca2+-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor. J Biol Chem 274: 27359-27370. [PubMed]

  11. Furukawa T, Yamanaka T, Midera T, Sagawa T, Mori Y & Nukada T (1999) Selectivities of dihydropyridine derivatives in blocking Ca2+ channel subtypes expressed in Xenopus oocytes. J Pharmacol Exp Ther 291: 464-473. [PubMed]

  12. Ishii H, Kinoshita E, Kimura T, Yakehiro M, Yamaoka K, Imoto K, Mori Y & Seyama I (1999) Point-mutations related to the loss of batrachotoxin binding abolish the gryanotoxin effect in Na+ channel isoforms. Jpn J Physiol 49: 457-461. [PubMed]

Other papers

  1. Uneyama H, Takahara A, Wakamori M, Mori Y & Yoshimoto R (1999) Pharmacology of N-type Ca2+ channels distributed in cardiovascular system. Int J Molecular Medecine 3: 455-466. [PubMed]

  2. 森 泰生 (1999) イオンチャネル. "脳と神経:分子神経生物科学入門" (金子 章道、川村 光毅、植村 慶一 編) pp. 128-136、共立出版、東京

  3. 森 泰生、小林 力 (1999) 電位依存性Ca2+チャネルの構造・機能と その異常.現代医療 31: 912-918.

  4. 井本 敬二 (1999) 電位依存性Na+チャネル. 現代医療 31: 905-911.

  5. 森 泰生、岡田 峯陽、清水 俊一 (1999) 受容体活性化される Ca2+流入機構:容量性Ca2+流入とTRP蛋白質. 日本薬理学雑誌 114: 149-160.

Publication list 1998

Original papers

  1. Wakamori M, Strobeck M, Niidome T, Teramoto T, Imoto K & Mori Y (1998) Functional characterization of ion permeation pathway in the N-type Ca2+ channel. J Neurophysiol 79:622-634. [PubMed]

  2. Mori Y, Takada Y, Okada T, Wakamori M, Imoto K, Wanifuchi H, Oka H, Oba A, Ikenaka K & Kurosaki K (1998) Differential distribution of TRP Ca2+ channel isoforms in mouse brain. NeuroReport 9:507-515. [PubMed]

  3. Okada T, Shimizu S, Wakamori M, Maeda A, Kurosaki T, Takada N, Imoto K & Mori Y (1998) Molecular cloning and functional characterization of a novel receptor-activated TRP Ca2+ channel from mouse brain. J Biol Chem 273:10279-10287. [PubMed]

  4. Wakamori M, Yamashita M & Ikemoto Y (1998) Halothane increases open probability of glycine-activated channel current in rat central neurones. Br J Anaesth 80:840-842. [PubMed]

  5. Nakai J, Sekiguchi N, Rando TA, Allen PD & Beam KG (1998) Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels. J Biol Chem 273:13403-13406. [PubMed]

  6. Furukawa T, Nukada T, Mori Y, Wakamori M, Fujita Y, Ishida H, Fukuda K, Kato S & Yoshii M (1998) Differential interactions of the C terminus and the cytoplasmic I-II loop of neuronal Ca2+ channels with G-protein alpha and beta-gamma subunits. I. molecular determination. J Biol Chem 273:17585-17594. [PubMed]

  7. Furukawa T, Miura R, Mori Y, Strobeck M, Suzuki K, Ogihara Y, Asano T, Morishita R, Hashii M, Higashida H, Yoshii M, Nukada T (1998) Differential interactions of the C terminus and the cytoplasmic I-II loop of neuronal Ca2+ channels with G-protein alpha and beta-gamma subunits. II. Evidence for direct binding. J Biol Chem 273:17595-17603 [PubMed]

  8. Yamazaki K, Okada T, Mori Y & Tanaka I (1998) Genetic mapping of mouse transient receptor potential (Trrp) genes responsible for capacitative calcium entry channels to chromosomes 3,7,9, and X. Genomics 51:303-305. [PubMed]

  9. Letts VA, Felix R, Biddlecome GH, Arikkath J, Mahaffey CL, Valenzuela A, Bartlett II FS, Mori Y, Campbell KP & Frankel WN (1998) The mouse stargazer gene encodes a neuronal Ca2+ channel gamma subunit. Nature Genetics 19:340-347. [PubMed]

  10. Nakai J, Tanabe T, Konno T, Adams BA & Beam KG (1998) Localization in the II-III loop of the dihydropyridine receptor of a sequence critical for excitation-contraction coupling. J Biol Chem 273:24983-24986. [PubMed]

  11. Wakamori M, Yamazaki K, Matsunodaira H, Teramoto T, Tanaka I, Niidome T, Sawada K, Nishizawa Y, Sekiguchi N, Mori E, Mori Y & Imoto K (1998) Single tottering mutations responsible for the neuropathic phenotype of the P-type calcium channel. J Biol Chem 273: 34857-34867. [PubMed]

Other papers

  1. 松山 善次郎、川上 秀史、村田 芳夫、中村 重信 (1998) Spinocerebellar ataxia type 6 (SCA6). 神経内科 49:238-242.

  2. 森 泰生 (1998) Ca2+チャネルの構造・機能とその病態. Mebio 6:44-53.

  3. 森 泰生、井本 敬二 (1988) 受容体活性化されるCa2+ 流入機構 容量性Ca2+流入とTRP蛋白質. 蛋白質核酸酵素 43:1567-1576.

  4. 井本 敬二 (1998) 神経から筋肉へ興奮伝達. “岩波講座  現代医学の基礎 第6巻 脳・神経の科学 I ニューロン”(久野 宗、三品 昌美 編)pp. 25-42、 岩波書店、東京.

  5. 宍戸 恵美子 (1998) ショウジョウバエのシナプス形成を制御する 新しいタンパク質Capricious. 実験医学 16:1917-1920.

  6. Kobayashi T & Mori Y (1998) Ca2+ channel antagonists and neuroprotection from cerebral ischemia. Eur J Pharmacol 363:1-15 .

Publication list 1997

Original papers

  1. Nakai J, Ogura T, Protasi F, Franzini-Armstrong C, Allen PD, Beam KG. (1997) Functional nonequality of the cardiac and skeletal ryanodine receptor, Proc Natl Acad Sci USA 94: 1019-1022.

  2. Garcia J, Nakai J, Imoto K, Beam K G (1997) Role of S4 Segments and the leucine heptad motif in the activation of an L-type calcium channel. Biophys J 72: 2515-2523.

  3. Dirksen RT, Nakai J, Gonzarez A, Imoto K, Beam KG (1997) The S5-S6 linker of repeat I is a critical determinant of L-type Ca2+ channel conductance. Biophys J 73: 1402-1409.

  4. Furukawa T, Nukada T, Suzuki K, Fujita Y, Mori Y, Nishimura M, Yamanaka M (1997) Voltage and pH dependent block of cloned N-type Ca2+ channels by amlodipine. Br J Parmacol 121: 1136-1140.

  5. Kobayashi T, Strobeck M, Schwartz A, Mori Y (1997) Inhibitory effects of a new neuroprotective dilitiazem analogue, T-477, on cloned brain Ca2+ channels expressed in Xenopus oocytes. Eur J Parmacol 332: 313-320.

  6. Nakashima Y, Nishimura S, Maeda A, Hakamata Y, Nakai J, Allen PD, Imoto K, Kita T. (1997) Molecular cloning and characterization of a human brain ryanodine receptor. FEBS Lett 417:157-162.

Other papers

  1. 井本 敬二 (1997) 神経系とカルシウム--分子生物学的研究の成果と 今後の問題点-- 小児神経学の進歩 第26集、129-138

  2. 中井 淳一 (1997) リアノジン受容体・カルシウム放出チャネルと悪性高熱 最新医学 51:36-41

  3. 井本 敬二 (1997) 分子生物学的実験のための準備と基礎技術. 日本生理学会誌 59:271-278

  4. 森 泰生 (1997) Mutagenesisによるレセプター、チャネルの 構造機能解析. 日本生理学会誌

  5. 森島 繁、森 泰生、井本 敬二 (1997) 電位依存性カチオンチャネルと 神経・筋・心疾患、In チャネルとトランスポーター:その働きと病気 分子医科学で病気を識るシリーズ 5 (岡田泰伸、清野 進 編) 78-100 メジカルビュー社、東京

Publication list 1996

Original papers

  1. Helmchen F, Imoto K, Sakmann B (1996) Ca2+ buffering and action potential evoked Ca2+ signaling in dendrites of pyramidal neurons. Biophys J 70: 1069-1081. [PubMed]

  2. Schlief T, Schonherr R, Imoto K, Heinemann SH. (1996) Pore characteristics of rat brainII channels mutated in the selectivity filter domain. European Biophys J 25: 75-91. [PubMed]

Other papers

  1. Mori Y, Mikala G, Varadi G, Kobayashi T, Koch S, Wakamori M, Schwartz A (1996) Molecular pharmacology of voltage-dependent calcium channels. Jap J Pharmacol 72: 83-109.

  2. 井本 敬二 (1996) Ca2+チャネルの構造と機能. Clinical Neuroscience 14,143-146,1996.

  3. 月田 承一郎、井本 敬二、高井 義美、大橋 正人 (1996) 細胞の構造と機能 −総説−. 月田 承一郎 編 ”分子医科学シリーズ 2 細胞:構造と機能” pp 1-42, メジカルビュー社.