Publication List (1997-2010)
2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997
2014
K. Sato-Numata, T. Numata & Y. Okada (2014) Temperature sensitivity
of acid-sensitive outwardly rectifying (ASOR) anion channels in cortical
neurons is involved in hypothermic neuroprotection against acidotoxic necrosis.
Channels (in press)
Y. Okada (2014) Significance of AVD in apoptosis induction: Requirements
for its careful examination in in vitro experiments. J. Physiol. (London)
On Line Issue (published on January 27, 2014): Comments for Cross Talk:
Rebuttal from S.N. Orlov, M.M. Model & R. Grygorczyk. J Physiol December
15, 2013 591 (24) 6129
T. Okada, T. Akita, K. Sato-Numata, M.R. Islam & Y. Okada (2014) A
newly cloned ClC-3 isoform, ClC-3d, as well as ClC-3a mediates Cd2+-sensitive outwardly rectifying anion currents. Cell. Physiol. Biochem. 33, 539-556
2013
K.Sato-Numata, T. Numata, T. Okada & Y. Okada (2013) Acid-sensitive outwardly rectifying (ASOR) anion channels in human epithelial cells are highly sensitive to temperature and independent of ClC-3. Pflügers Arch. 465, 1535-1543
T. Shimizu, T.Iehara, K. Sato, T. Fujii, H. Sakai & Y. Okada (2013) TMEM16F is a component of a Ca2+-activated Cl− channel but not a volume-sensitive outwardly rectifying Cl− channel. Am. J. Physiol. Cell Physiol.304, C748-C759
R.Z. Sabirov, R.S. Kurbannazarova, N.R. Melanova, Y. Okada (2013) Volume-sensitive anion channels mediate osmosensitive glutathione release from rat thymocytes. PLoS One 8(1), e55646
2012
E. Maeno, T. Tsubata & Y. Okada (2012) Apoptotic volume decrease (AVD) is independent of mitochondrial dysfunction and initiator caspase activation. Cells 1, 1156-1167
H. Uramoto, T. Okada & Y. Okada (2012) Protective role of cardiac CFTR activation upon early reperfusion against myocardial infarction. Cell. Physiol. Biochem. 30, 1023-1038
Y. Hasegawa, T. Shimizu, N. Takahashi & Y. Okada (2012) The apoptotic volume decrease is an upstream event of MAP kinase activation during staurosporine-induced apoptosis in HeLa cells. Int. J. Mol. Sci. 13, 9363-9379
Y. Okada (ed.) (2012) “Patch Clamp Techniques - From Beginning to Advanced Protocols” Springer, Tokyo, 439pp
T. Akita, M. Ohara & Y. Okada (2012) Patch-clamp techniques: General remarks. In,“Patch Clamp Techniques - From Beginning to Advanced Protocols” (ed. Y. Okada), pp21-42, Springer, Tokyo
R.Z. Sabirov, Y.E. Korchev & Y. Okada (2012) Smart-patch technique. In,“Patch Clamp Techniques - From Beginning to Advanced Protocols” (ed. Y. Okada), pp379-388, Springer, Tokyo
R.Z. Sabirov & Y. Okada (2012) Ion channel pore sizing in patch-clamp experiments. In,“Patch Clamp Techniques - From Beginning to Advanced Protocols” (ed. Y. Okada), pp389-402, Springer, Tokyo
H. Matsumoto, K. Shibasaki, M. Uchigashima, A. Koizumi, M. Kurachi, Y. Moriwaki, H. Misawa, K. Kawashima, M. Watanabe, S. Kishi & Y. Ishizaki (2012) Localization of acetylcholine-related molecules in the retina: Implication of the communication from photoreceptor to retinal pigment epithelium. PLoS One (in press)
A. Koizumi, K.F. Tanaka & A. Yamanaka (2012) Manipulation of neuronal and cellular activity by ectopic expression of Melanopsin. Neurosci. Res. (in press)
T. Tsunematsu, K.F. Tanaka, A. Yamanaka & A. Koizumi (2012) Ectopic expression of melanopsin in orexin/hypocretin neurons enables control of wakefulness of mice in vivo by blue light. Neurosci. Res. (in press)
M. R. Islam, H. Uramoto, T. Okada, R.Z. Sabirov & Y. Okada (2012) Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells. Am. J. Physiol. Cell Physiol. 303, C924-C935
K. Dezaki, E. Maeno, K. Sato, T. Akita & Y. Okada (2012) Early-phase occurrence of K+ and Cl- efflux in addition to Ca2+ mobilization is a prerequisite to apoptosis in HeLa cells. Apoptosis 17, 821-831
Y. Ando-Akatsuka,T. Shimizu, T. Numata & Y. Okada (2012) Involvements of the ABC protein ABCF2 and α-actinin-4 in regulation of cell volume and anion channels in human epithelial cells. J Cell Physiol 227, 3498-3510
T. Numata, K. Sato, J. Christmann, R. Marx, Y. Mori, Y. Okada & F. Wehner (2012) The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel (HICC) in HeLa cells, and the ecto-enzyme CD38 mediates its activation. J Physiol (London) 590, 1121-1138
2011
T. Akita, S.V. Fedorovich & Y. Okada (2011) Ca2+ nanodomain-mediated component of swelling-induced volume-sensitive outwardly rectifying anion current triggered by autocrine action of ATP in mouse astrocytes. Cell Physiol Biochem 28, 1181-1190
S. Moritoh, K. Sato, Y. Okada & A. Koizumi (2011) Endogenous ATP positive retinal cells in AVP-eGFP transgenic rat identified by immunohistochemistry and RT-PCR. Molecular Vision 17, 3254-3261
R.S. Kurbannazarova, S.V. Bessonova, Y. Okada & R.Z. Sabirov (2011) Swelling-activated anion channels are essential for volume regulation of mouse thymocytes. Int. J. Mol. Sci. 12, 9125-9137
T. Akita & Y. Okada (2011) Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca2+ nanodomains in mouse astrocytes. J. Physiol. (London) 589, 3909-3927
O.V. Krasilnikov, R.Z. Sabirov & Y. Okada (2011) ATP hydrolysis-dependent asymmetry of the conformation of CFTR channel pore. J. Physiol. Sci. 61, 267-278
K. Sato, T. Numata, T. Saito, Y. Ueta & Y. Okada (2011) V2 receptor-mediated autocrine role of somatodendritic releas e of AVP in rat vasopressin neurons under hypo-osmotic conditions. Science Signaling 4 (157), ra5
2010
S. Moritoh, K.F. Tanaka, H. Jouhou, K. Ikenaka & A. Koizumi (2010) Organotypic tissue culture of adult rodent retina followed by particle-mediated acute gene transfer in vitro. PLoS One 5, e12917
A. Koizumi, M. Takayasu & H. Takayasu (2010) Asymmetric inhibitory connections enhance directional selectivity in a three-layer simulation model of retinal networks. J. Integr. Neurosci. 9, 337-350
T. Ohbuchi, K. Sato, H. Suzuki, Y. Okada, G. Dayanithi, D. Murphy & Y. Ueta (2010) Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus. J. Physiol. 588, 2147-2162
H. Inoue, N. Takahashi, Y. Okada & M. Konishi (2010) Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice. Am. J. Physiol. Cell Physiol. 298, C900-C909
M. Subramanyam, N. Takahashi, Y. Hasegawa, T. Mohri & Y. Okada (2010) Inhibition of a protein kinase Akt1 by apoptosis signal-regulating kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase. J. Biol. Chem. 285, 6109-6117
A.F. James, R.Z Sabirov & Y. Okada (2010) Clustering of protein kinase
A-dependent CFTR chloride channels in the sarcole mma of guinea-pig ventricular
myocytes. Biochem. Biophys. Res. Commun. 391, 841-845
2009
A.F. James, R.Z Sabirov & Y. Okada (2009) Clustering of protein kinase A-dependent CFTR chloride channels in the sarcolem ma of guinea-pig ventricular myocytes. Biochem. Biophys. Res. Commun. (in press) [doi: 10.1016/j.bbrc.2009.11.149]A.H. Toychiev, R.Z. Sabirov, N. Takahashi, Y. Ando-Akatsuka, H.-T Liu, T. Shintani, M. Noda & Y. Okada (2009) Activati on of the maxi-anion channel by protein tyrosine dephosphorylation. Am. J. Physiol. Cell Physiol. 297, C990-C1000
H.-T. Liu, T. Akita, T. Shimizu, R.Z. Sabirov & Y. Okada (2009) Bradykinin-induced astrocyte-neuron signaling: glutamat e release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels. J. Physiol. (London) 587, 2197-2209
Y. Okada, K. Sato & T. Numata (2009) Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel. J. Physiol. (London) 587, 2141-2149
Y. Okada, K. Sato, A.H. Toychiev, M. Suzuki, A.K. Dutta, H. Inoue & R.Z. Sabirov (2009) The puzzles of volume-activated anion channels. In, "Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecule s to Diseases" (eds. F.J. Alvarez-Leefmans & E. Delpire), Elsevier, San Diego, pp 283-306
R. Z. Sabirov & Y. Okada (2009) The maxi-anion channel: A classical
channel playing novel roles through an unidentified molecular entity. J. Physiol. Sci. 59, 3-21
2008
P. Fuerst, A. Koizumi, R.H. Masland & R. Burges (2008) Neurite arborization
and mosaic spacing in the mouse retina require DSCAM. Nature. 451, 470-474
Y. Okada, A. Matsumoto, T. Shimazaki, R. Enoki, A. Koizumi, S. Ishii, Y. Itoyama, G. Sobue & H. Okano (2008) Spatio-Temporal Recapitulation of Central Nervous System Development By Murine ES Cell-Derived Neural Stem/Progenitor Cells. Stem Cells. 26, 3086-98
T.C. Jakobs, A. Koizumi & R.H. Masland (2008) The spatial distribution of glutamatergic inputs to dendrites of retinal ganglion cells. J. Comp. Neurol. 510, 221-36
B. Lin, A. Koizumi, N. Tanaka, S. Panda & R.H. Masland (2008) Restoration of visual function in retinal degeneration mice by ectopic expression of melanopsin. Proc. Natl. Acad. Sci. U. S. A. 105,16009-14
T. Numata & Y. Okada (2008) Molecular determinants of sensitivity and conductivity of human TRPM7 to Mg2+ and Ca2+. Channels 2, 283-286E.L. Lee, Y. Hasegawa, T. Shimizu & Y. Okada (2008) IK1 channel activity contributes to cisplatin sensitivity of human epidermoid cancer cells. Am. J. Physiol. Cell Physiol. 294, C1398 - C1406
T. Numata, K. Sato, Y. Okada & F. Wehner (2008) Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis. Apoptosis 13, 895-903
T. Numata & Y. Okada (2008) Proton conductivity through the human TRPM7 channel and its molecular determinants. J. Biol. Chem. 283, 15097-15103
H.-T. Liu, R.Z. Sabirov & Y. Okada (2008) Oxygen-glucose deprivation induces ATP release via maxi-anion channels in as trocytes. Purinergic Signalling 4, 147-154
H.-T. Liu, A.H. Toychiev, N. Takahashi, R.Z. Sabirov & Y. Okada (2008) Maxi-anion channel as a candidate pathway for osmosensitive ATP release from mouse astrocytes in primary culture. Cell Research 18, 558-565
A.K. Dutta, Y.E. Korchev, A.I. Shevchuk, S. Hayashi, Y. Okada & R.Z. Sabirov (2008) Spatial distribution of maxi-anion c hannel on cardiomyocytes detected by smart-patch technique. Biophys. J. 94, 1646-1655
T. Shimizu, E.L. Lee & Y. Okada (2008) Voleme-sensitive Cl channel
as a regulator of acquired cisplatin resistance. Anticancer Res. 28, 75-84
2007
T. Shimizu, E. Maeno & Y. Okada (2007) Prerequisite role of persistent
cell shrinkage in apoptosis of human epithelial cells. Acta Physiologica Sinica 59, 512-516
M.V. Zamaraeva, R.Z. Sabirov, K. Manabe & Y. Okada (2007) Ca2+-dependent glycolysis activation mediates apoptotic ATP elevation in HeLa cells.
Biochem. Biophys. Res. Commun. 363, 687-693
T. Numata, F. Wehner & Y. Okada (2007) A novel inhibitor of hypertonicity-induced
cation channels in HeLa cells. J. Physiol. Sci. 57, 249-252
H. Inoue, H. Ohtaki, T. Nakamachi, S. Shioda & Y. Okada (2007) Anion
channel blockers attenuate delayed neuronal cell death induced by transient
forebrain ischemia. J. Neurosci. Res. 85, 1427-1435
F. Wehner, T. Numata, M. Subramaniam, N. Takahashi & Y. Okada (2007)
Signalling events employed in the hypertonic activation of cation channels
in HeLa cells. Cell. Physiol. Biochem. 20, 75-82
H.-Y. Wang, T. Shimizu, T. Numata & Y. Okada (2007) Role of acid-sensitive
outwardly rectifying anion channels in acidosis-induced cell death in human
epithelial cells Pflugers Arch. Eur. J. Physiol. 454, 223-233
E.L. Lee, T. Shimizu, T. Ise, T. Numata, K. Kohno & Y. Okada (2007)
Impaired activity of volume-sensitive Cl channel is involved in cisplatin
resistance of cancer cells. J. Cell. Physiol. 211, 513-521
H. Inoue & Y. Okada (2007) Role of volume-sensitive chloride channel
in excitotoxic neuronal injury. J. Neurosci. 27, 1445-1455
T. Numata, T. Shimizu & Y. Okada (2007) Direct mechano-stress sensitivity of TRPM7 channel. Cell. Physiol. Biochem. 19, 01-08
T. Numata, T. Shimizu & Y. Okada (2007) TRPM7 is a stretch- and swelling-activated
cation channel involved in volume regulation in human epithelial cells.
Am. J. Physiol. Cell Physiol. 292, C460-C467
2006
T. Shimizu, F. Wehner & Y. Okada (2006) Inhibition of hypertonicity-induced
cation channels sensitizes HeLa cells to shrinkage-induced apoptosis.
Cell. Physiol. Biochem. 18, 295-302
E. Maeno, N. Takahashi & Y. Okada (2006) Dysfunction of regulatory
volume increase is a key component of apoptosis. FEBS Lett. 580, 6513-6517
Y. Okada, T. Shimizu, E. Maeno, S. Tanabe, X. Wang & N. Takahashi (2006)
Volume-sensitive chloride channels involved in apoptotic volume decrease
and cell death. J. Membrane Biol. 209, 21-29
Y. Okada (2006) Foreword: Ion channel roles in cell death induction. J.Membrane Biol. 209, 1-2
Y. Okada (2006) Cell volume-sensitive chloride channel: Phenotypic properties
and molecular identity. In, "Mechanisms and Significance of Cell Volume
Regulation" (ed. F. Lang), pp 9-24 Karger, Basel
M. Nukui, T. Shimizu & Y.Okada (2006) Normotonic cell shrinkage induced by Na+ deprivation results in apoptotic cell death in human epithelial HeLa cells. J. Physiol. Sci. 56, 335-339
H.-T. Liu, B.A. Tashmukhamedov, H. Inoue, Y. Okada & R.Z. Sabirov
(2006) Roles of two types of anion channels in glutamate release from
mouse astrocytes under ischemic or osmotic stress. Glia 54, 343-357
E. Maeno, T. Shimizu & Y. Okada (2006) Normotonic cell shrinkage induces apoptosis under extracellular low Cl- conditio ns in human lymphoid and epithelial cells. Acta Physiologica 187, 217-222
R.Z. Sabirov, T. Sheiko, H.-T. Liu, D. Deng, Y. Okada & W.J. Craigen
(2006) Genetic demonstration that the plasma membrane maxi-anion channel
and voltage-dependent anion channels (VDACS) are unrelated proteins. J. Biol. Chem. 281, 1897-1904
2005
H. Kida, T. Miyoshi, K. Manabe, N. Takahashi, T. Konno, S. Ueda, T. Chiba,
T. Shimizu, Y. Okada & S. Morishima (2005) Roles of aquaporin-3 water
channels in volume-regulatory water flow in a human epithelial cell line.
J. Membrane Biol. 208, 55-64
J. Wang, H. Xu, S. Morishima, S. Tanabe, K. Jishage, S. Uchida, S. Sasaki, Y. Okada & T. Shimizu (2005) Single-channel p roperties of volume-sensitive Cl- channel in ClC-3-deficient cardiomyocytes. Jpn. J. Physiol. 55, 379-383
T. Ise, T. Shimizu, E.L. Lee, H. Inoue, K. Kohno & Y. Okada (2005) Roles of volume-sensitive Cl- channel in cisplatin-induced apoptosis in human epidermoid cancer cells. J. Membrane Biol. 205, 139-145
R. Z. Sabirov & Y. Okada (2005) ATP release via anion channels. Purinergic Signalling 1, 311-328
X. Wang, N. Takahashi, H. Uramoto & Y. Okada (2005) Chloride channel inhibition prevents ROS-dependent apoptosis induced by ischemia-reperfusion in mouse cardiomyocytes. Cell. Physiol. Biochem. 16, 147-154
Y. Okamura, A. Nishino, Y. Murata, K. Nakajo, H. Iwasaki, Y. Ohtsuka, M.
Tanaka-Kunishima, N. Takahashi, Y. Hara, T. Yos hida, M. Nishida, H. Okado,
H. Watari, I. A. Meinertzhagen, N. Satoh, K. Takahashi, Y. Satou, Y. Okada
& Y. Mori (2005) Comprehensive analysis of the ascidian genome reveals
novel insights into the molecular evolution of ion channel genes. Physiolog. Genomics 22, 269-282
M.V. Zamaraeva, R.Z. Sabirov, E. Maeno, Y. Ando-Akatsuka, S.V. Bessonova
& Y. Okada (2005) Cells die with increased cyt osolic ATP during apoptosis:
A bioluminescence study with intracellular luciferase. Cell Death & Differentiation 12, 1390-1397
H. Inoue, S. Mori, S. Morishima & Y. Okada (2005) Volume-sensitive chloride channels in mouse cortical neurons: characterization and role in volume regulation. Eur. J. Neurosci. 21, 1648-1658
N. Takahashi, X.-M. Wang, S. Tanabe, H. Uramoto, K. Jishage, S. Uchida, S. Sasaki & Y. Okada (2005) ClC-3-independent se nsitivity of apoptosis to Cl- channel blockers in mouse cardiomyocytes. Cell. Physiol. Biochem. 15, 263-270
Y. Okada, E. Maeno, T. Nabekura & S. Mori (2005) Essential role of anion channel in induction of apoptotic and necrotic cell death. In "Ion Channels in the Pulmonary Vasculature" (ed. J. X.-J. Yuan), pp 527-544, Taylor & Francis: Boca Raton, FL
S. Tanabe, X.-M. Wang, N. Takahashi, H. Uramoto & Y. Okada (2005) HCO3--independent rescue
from apoptosis by stilbene derivatives in rat cardiomyocytes. FEBS
Lett. 579, 517-522
2004
Y. Okada, E. Maeno & S. Mori (2004) Anion channel involved in induction
of apoptosis and necrosis. In, "Cell Volume and Signaling" (Eds. Lauf PK & Adragna NC),
pp 205-209, Springer, NY
S. Hayashi, A. Hazama, A. K. Dutta, R. Z. Sabirov & Y. Okada (2004) Detecting ATP release by a biosensor method. Sci. STKE 2004 258, pl-14
V.I. Ternovsky, Y. Okada & R.Z. Sabirov (2004) Sizing the pore of the volume-sensitive anion channel by differential polymer partitioning. .FEBS Lett. . 576, 433-436
A.K. Dutta, R.Z. Sabirov, H. Uramoto & Y. Okada (2004) Role of ATP-conductive anion channel in ATP release from neonatal rat cardiomyocytes in ischemic or hypoxic conditions. J. Physiol. (London) 559, 799-812
K. Manabe, T. Shimizu, S. Morishima & Y. Okada (2004) Regulatory volume increase after secretory volume decrease in colonic epithelial cells under muscarinic stimulation. Pflugers Arch. Eur. J. Physiol. 448, 596-604
R.Z. Sabirov & Y. Okada (2004) Wide nanoscopic pore of maxi-anion channel suits its function as an ATP-conductive pathway. Biophys. J. 87, 1672-1685
T. Shimizu, T. Numata & Y. Okada (2004) A role of reactive oxygen species in apoptotic activation of volume-sensitive Cl- channel. Proc. Natl. Acad. Sci. USA 101, 6770-6773
W. Gong, H. Xu, T. Shimizu, S. Morishima, S. Tanabe, T. Tachibe, S. Uchida, S. Sasaki & Y. Okada (2004) ClC-3-independent, PKC-dependent activity of volume-sensitive Cl- channel in mouse ventricular cardiomyocytes. Cell. Physiol. Biochem. 14, 213-224
Y. Okada, E. Maeno, T. Shimizu, K. Manabe, S. Mori & T. Nabekura (2004) Dual roles of plasmalemmal chloride channels in induction of cell death. Pflugers Arch. Eur. J. Physiol. 448, 287-295
Ravshan Z. Sabirov and Yasunobu Okada (2004) ATP-conducting maxi-anion channel: A new player in stress-sensory transduction. Jpn. J. Physiol. 54, 7-14
Y. Okada (2004) Ion channels and transporters involved in cell volume regulation and sensor mechanisms. Cell Biochem. Biophys. 41, 233-258
X.-D. Zhang, S. Morishima, Y. Ando-Akatsuka, N. Takahashi, T. Nabekura,
H. Inoue, T. Shimizu & Y. Okada (2004) Expression of novel isoforms
of the ClC-1 chloride channel in astrocytic glial cells in vitro. Glia 47, 46-57
2003
H. Uramoto, N. Takahashi, A.K. Dutta, R.Z. Sabirov, Y. Ando-Akatsuka, S.
Morishima & Y. Okada (2003) Ischemia-induced enhancement of CFTR expression
on the plasma membrane in neonatal rat ventricular myocytes. Jpn.
J. Physiol. 53, 357-365
H. Ohtaki, S. Mori, T. Nakamachi, K. Dohi, L. Yin, S. Endo, Y. Okada & S. Shioda (2003) Evaluation of neuronal cell death after a new global ischemia model in infant mice. Acta Neurochir. Suppl. 86, 97-100
F. Wehner, T. Shimizu, R. Sabirov & Y. Okada (2003) Hypertonic activation of a non-selective cation conductance in HeLa cells and its contribution to cell volume regulation. FEBS Lett. 551, 20-24
Y. Okada, E. Maeno, T. Nabekura & S. Mori (2003) Prerequisite roles of anion channel in induction of apoptotic and necrotic cell death. In "Ion Channels in the Pulmonary Vasculature" (ed. J. X.-J. Yuan) Marcel Dekker, NY (in press)
J.-Y. Lapointe, P.D. Bell, R.Z. Sabirov & Y. Okada (2003) Calcium-activated non-selective cation channel in macula densa cells. Am. J. Physiol. 285, F275-F280
L.F. Barros, T. Kanaseki, R. Sabirov, S. Morishima, J. Castro, C.X. Bittner, E. Maeno, Y. Ando-Akatsuka & Y. Okada (2003) Apoptotic and necrotic blebs in epithelial cells display similar neck diameters but different kinase dependency. Cell Death Differ. 10, 687-697
I.F. Abdullaev, R.Z. Sabirov & Y. Okada (2003) Upregulation of swelling-activated Cl- channel sensitivity to cell volume by activation of EGF receptors in murine mammary cells. J. Physiol. (London) 549, 749-758
P.D. Bell, J.-Y. Lapointe, R.Z. Sabirov, S. Hayashi, J. Peti-Peterdi, K. Manabe, G. Kovacs & Y. Okada (2003) Macula densa cell signaling involves ATP release through a maxi anion channel. Proc. Natl. Acad. Sci. (USA) 100, 4322-4327
T. Nabekura, S. Morishima, T.L. Cover, S. Mori, H. Kannan, S. Komune & Y. Okada (2003) Recovery from lactacidosis-induced glial cell swelling with the aid of exogenous anion channels. Glia 41, 247-259
J. Wang, S. Morishima & Y. Okada (2003) IK channels are involved in
the regulatory volume decrease in human epithelial cells. Am. J. Physiol. 284, C77-C84
2002
S. Mori, S. Morishima, M. Takasaki & Y. Okada (2002) Impaired activity
of volume-sensitive anion channel during lactacidosis-induced swelling
in neuronally differentiated NG108-15 cells. Brain Res. 957,
1-11
Y. Ando-Akatsuka, I.F. Abdullaev, E.L. Lee, Y. Okada & R.Z. Sabirov
(2002) Down-regulation of volume-sensitive Cl- channels by CFTR is mediated by the second nucleotide-binding
domain. Pflugers Arch. Eur. J. Physiol. 445, 177-186
A.K. Dutta, Y. Okada & R.Z. Sabirov (2002) Regulation of an ATP-conductive
large-conductance anion channel and swelling-induced ATP release by arachidonic
acid. J. Physiol.
(London) 542, 803-816
S.-S. Zhou, A. Takai & Y. Okada (2002) Regulation of cardiac CFTR Cl- channel activity by
a Mg2+-dependent protein phosphatase. Pflugers Arch. Eur.
J. Physiol. 444, 327-334
J. Peti-Peterdi, S. Morishima, P.D. Bell & Y. Okada (2002) Two-photon
excitation fluorescence imaging of the living juxtaglomerular apparatus.
Am. J. Physiol. 283,
F197-F201
Y. Hara, M. Wakamori, M. Ishii, E. Maeno, M. Nishida, T. Yoshida, H. Yamada,
S. Shimizu, E. Mori, J. Kudoh, N. Shimizu, H. Kurose, Y. Okada, K.Imoto
& Y. Mori (2002) LTRPC2 Ca2+-permeable
channel activated by changes in redox status confers susceptibility to
cell death. Molecular Cell 9, 163-173
2001
Y. Okada, E. Maeno, T. Shimizu, K. Dezaki, J. Wang & S. Morishima.
(2001) Receptor-mediated control of regulatory volume decrease (RVD) and
apoptotic volume decrease (AVD). J. Physiol. (London) 532, 3-16 [Topical
Review]
R.Z. Sabirov, A.K. Dutta & Y. Okada. (2001) Volume-dependent ATP-conductive large-conductance anion channel as a pathway for swelling-induced ATP release. J. Gen. Physiol. 118, 251-266
H.-T. Fan, S. Morishima, H. Kida & Y. Okada. (2001) Phloretin differentially inhibits volume-sensitive and cAMP-activated, but not Ca-activated, Cl- channels. Br. J. Pharmacol. 133, 1096-1106
Y. Okada & E. Maeno. (2001) Apoptosis, cell volume regulation and volume-regulatory
chloride channels. Comp. Biochem. Physiol. Part A. 130, 377-383
2000
S. Shimizu, S. Morishima & Y. Okada (2000) Ca2+-sensing receptor-mediated
regulation of volume-sensitive Cl- channels in human epithelial
cells. J. Physiol. (London) 528, 457-472
A. Hazama, H. Fan, I. Abdullaev, E. Maeno, S. Tanaka, Y. Ando-Akatsuka & Y. Okada (2000) Swelling-activated, cystic fibrosis transmembrane conductance regulator-augmented ATP release and Cl- conductances in C127 cells. J. Physiol. (London) 523, 1-11
K. Dezaki, T. Tsumura, E. Maeno & Y. Okada (2000) Receptor-mediated facilitation of cell volume regulation by swelling-induced ATP release in human epithelial cells. Jpn. J. Physiol. 50, 235-241
S. Morishima, T. Shimizu, H. Kida & Y. Okada (2000) Volume expansion sensitivity of swelling-activated Cl- channel in human epithelial cells. Jpn. J. Physiol. 50, 277-280
E. Maeno, Y. Ishizaki, T. Kanaseki, A. Hazama & Y. Okada (2000) Normotonic cell shrinkage due to disordered volume regulation is an early prerequisite to apoptosis. Proc. Natl. Acad. Sci. USA 97, 9487-9492
Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E. M. Wright (eds). (2000) "Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels" Elsevier, Amsterdam
A. Hazama, Y. Ando-Akatsuka, H.-T. Fan, S. Tanaka & Y. Okada. (2000) CFTR-dependent and -independent ATP release induced by osmotic swelling. In, ""Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels" (eds. Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E. M. Wright) pp 429-431.Elsevier, Amsterdam
T. Shimizu, S. Morishima & Y. Okada. (2000) Effect of extracellular Ca2+ on volume sensitivity of the swelling-activated Cl- channel in human epithelial cells. In, "Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels" (eds. Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E. M. Wright) pp 271-272, Elsevier, Amsterdam
H.-T. Fan, H. Kida, S. Morishima & Y. Okada. (2000) Phloretin inhibits a regulatory volume decrease in human epithelial cells. In, "Control and Disease of Sodium Dependent Transportation Proteins and Ion Channels" (eds. Y. Suketa, E. Carafoli, M. Lazdunski, K. Mikoshiba, Y. Okada & E. M. Wright) pp 281-282, Elsevier, Amsterdam
Y. Okada, A. Hazama, I. Abdullaev, S. Tanaka, Y. Ando-Akatsuka, T. Shimizu,
R. Z. Sabirov, S. Hayashi & H.-T. Fan. (2000) Cell volume-sensitive
Cl- channel and ATP release. In, "Control and Disease of Sodium Dependent
Transportation Proteins and Ion Channels" (eds. Y. Suketa, E. Carafoli,
M. Lazdunski, K. Mikoshiba, Y. Okada & E. M. Wright) pp 261-264, Elsevier,
Amsterdam
1999
Hazama A, Shimizu T, Ando-Akatsuka Y, Hayashi S, Tanaka S, Maeno E &
Okada Y (1999) Swelling-induced, CFTR-independent ATP release from a human
epithelial cell line. Lack of correlation with volume-sensitive Cl-
channels. J Gen Physiol 114, 525-533
Sabirov RZ, Azimov RR, Ando-Akatsuka Y, Miyoshi T & Okada Y (1999) Na+ sensitivity of ROMK1 K+ channel: Role of the Na+/H+ antiporter. J Membrane Biol 172, 67-76
Okada Y (1999) A scaffolding
for regulation of volume-sensitive Cl- channels. J Physiol
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1998
Nakamura T, Arii S, Monden K, Furutani M, Takeda Y, Imamura M, Tominaga M & Okada Y (1998) Expression of the Na/Ca exchanger emerges in hepatic stellate cells after activation in association with liver fibrosis. Proc Natl Acad Sci USA 95, 5389-5394.
Liu Y, Oiki S, Tsumura T, Shimizu T & Okada Y (1998) Glibenclamide blocks volume-sensitive Cl- channels by dual mechanisms. Am J Physiol 275, C343-C351.
Okada Y, Oiki S, Hazama A & Morishima S (1998) Criteria for the molecular identification of the volume-sensitive outwardly rectifying Cl- channel. J Gen Physiol 112, 1-3.
Tsumura T, Hazama A, Miyoshi T, Ueda S & Okada Y (1998) Activation of cAMP-dependent Cl- currents in guinea-pig Paneth cells without relevant evidence for CFTR expression. J Physiol (London) 512, 765-777.
Zhou S-S, Hazama A & Okada Y (1998) Tyrosine kinase-independent extracellular action of genistein on the CFTR Cl- channel in guinea pig ventricular myocytes and CFTR-transfected mouse fibroblasts. Jpn J Physiol 48, 389-396.
Hazama A, Hayashi S & Okada Y (1998) Cell surface measurements of ATP release from single pancreatic b cells using a novel biosensor technique. Pflugers Arch Eur J Physiol 437, 31-35.
Higuchi T, Suga S, Tsuchiya T, Hisada H, Morishima S, Okada Y & Maeshima M (1998) Molecular cloning, water channel activity and tissue specific expression of two isomers of radish vacuolar aquaporin. Plant Cell Physiol 39, 905-913.
Sabirov RZ, Morishima S & Okada Y (1998) Probing the water permeability of ROMK1 and amphotericin B channels using Xenopus oocytes. Biochim Biophys Acta 1368, 19-26.
Okada Y (ed.) (1998) "Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery" Elsevier, Amsterdam
Okada Y, Tominaga M, Tominaga T, Hazama A, Tsumura T, Morishima S, Oiki S, Ueda K, Miyoshi T & Miwa A (1998) Volume sensor anion channel. In "Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery" (ed. Okada Y) pp 15 - 22, Elsevier, Amsterdam.
Hazama A, Miwa A, Miyoshi T, Shimizu T & Okada Y (1998) ATP release from swollen or CFTR-expressing epithelial cells. In "Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery" (ed. Okada Y) pp 93 - 98, Elsevier, Amsterdam.
Oiki S, Kubo M & Okada Y (1998) Electrophysiological properties of volume-regulated Cl- channels in intestinal epithelial cells. In "Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery" (ed. Okada Y) pp 125-129, Elsevier, Amsterdam.
Morishima S, Kida H, Ueda S, Chiba T & Okada Y (1998) Water movement during cell volume regulation. In "Cell Volume Regulation: The Molecular Mechanism and Volume Sensing Machinery" (ed. Okada Y) pp 209 - 212, Elsevier, Amsterdam.
Okada Y (1998) Cell volume-sensitive
chloride channel. In "Cell Volume Regulation" (ed. Lang F) (Contrib.
Nephrol. vol. 123) pp 21-33, Karger, Basel.
1997
A. Miwa, K. Ueda & Y. Okada. (1997) Protein kinase C-independent correlation
between P-glycoprotein expression and volume sensitivity of Cl-
channel. J. Membrane Biol. 157, 63-69
R.Z. Sabirov, Y. Okada & S. Oiki. (1997) Two-sided action of protons on an inward rectifier K+ channel. Pflugers Arch. Eur. J. Physiol. 433, 428-434
S.-S. Zhou, A. Takai & Y. Okada. (1997) Phosphatase-mediated enhancement of cardiac cAMP-activated Cl- conductance by a Cl- channel blocker, anthracene-9-carbocylate. Circul. Res. 81, 219-228
Y. Liu, J. Zhao, Y.-H. Ji, S. Oiki, A. Hazama, S. Morishima, R. Sabirov, S.-S. Zhou, S. Hayashi, T. Tsumura, T. Ito, K. Furuya & Y. Okada. (1997) The venom of scorpion B. martensi selectively inhibits transient outward K+ currents in neonatal rat ventricular cells and Kv+ channel currents in NG108-15 cells. Biomed. Res. 18, 383-388
R.Z. Sabirov, T. Tominaga, A. Miwa, Y. Okada & S. Oiki. (1997) A conserved arginine residue in the pore region of an inward rectifier K channel (IRK1) as an external barrier for cationic blockers. J. Gen. Physiol. 110, 665-677
Y. Okada, S. Okiki, M. Tominaga, M. Kubo, A. Miwa, T. Tominaga, T. Tsumura & K. Ueda. (1997) Volume-sensitive Cl- channel in human epithelial cells: Regulation by ATP and relation to P-glycoprotein. Jpn. J. Physiol. 47 (Suppl. 1) S19-S20
Y. Okada. (1997) Volume expansion-sensing outward rectifier Cl channel: A fresh start to the molecular identity and volume sensor. Am. J. Physiol. 273, C755-C789
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