2016

Masataka Kunii, Mica Ohara-Imaizumi, Noriko Takahashi, Masaki Kobayashi, Ryosuke Kawakami, Yasumitsu Kondoh, Takeshi Shimizu, Siro Simizu, Bangzhong Lin, Kazuto Nunomura, Kyota Aoyagi, Mitsuyo Ohno, Masaki Ohmuraya, Takashi Sato, Shin-ichiro Yoshimura, Ken Sato, Reiko Harada, Yoon-Jeong Kim, Hiroyuki Osada, Tomomi Nemoto, Haruo Kasai, Tadahiro Kitamura, Shinya Nagamatsu, and Akihiro Harada
“The opposite roles of SNAP23 in the exocrine and endocrine pancreas”
J. Cell Biol. vol. 215(1), pp. 121- 138,(2016) DOI: 10.1083/jcb.201604030

Ayano Tanabe, Terumasa Hibi, Sari Ipponjima, Kenji Matsumoto, Masafumi Yokoyama, Makoto Kurihara, Nobuyuki Hashimoto, Tomomi Nemoto
“Transmissive liquid crystal device for correcting primary coma aberration and astigmatism in biospecimen in two-photon excitation laser scanning microscopy”,
J. Biomed. Opt. vol. 21, No. 12, 121503-1 - 121503-10, (2016) doi: 10.1117/1.JBO.21.12.121503

Ayano Tanabe, Terumasa Hibi, Sari Ipponjima, Kenji Matsumoto, Masafumi Yokoyama, Makoto Kurihara, Nobuyuki Hashimoto, Tomomi Nemoto
“Transmissive liquid-crystal device correcting primary coma aberration and astigmatism in laser scanning microscopy”,
Proc. SPIE, p . 9717-1 (2016)　 doi:10.1117/12.2209459

2015

Ayano Tanabe, Terumasa Hibi, Sari Ipponjima, Kenji Matsumoto, Masafumi Yokoyama, Makoto Kurihara, Nobuyuki Hashimoto, Tomomi Nemoto
”Correcting spherical aberrations in biospecimen using transmissive liquid crystal device in two-photon excitation laser scanning microscopy”
J. Biomed. Opt. 20(10), pp: 101204-1 – 101204-11 (2015)

Kohei Otomo, Terumasa Hibi, Takashi Murata, Hirotaka Watanabe, Ryosuke Kawakami, Hiroshi Nakayama, Mitsuyasu Hasebe, Tomomi Nemoto
“Multi-point scanning two-photon excitation microscopy utilising a high-peak-power 1042-nm laser”
Anal. Sci. Vol. 31, No. 4, pp. 307-313. (2015) 表紙に採用, Hot Article Award受賞

Ryosuke Kawakami, Kazuaki Sawada, Yuta Kusama, Yi-Cheng Fang, Shinya Kanazawa, Yuichi Kozawa, Shunichi Sato, Hiroyuki Yokoyama and　Tomomi Nemoto
“In vivo two-photon imaging of mouse hippocampal neurons in dentate gyrus using a light source based on a high-peak power gain-switched laser diode”
Biomed. Opt. Express Vol. 6, Issue 3, pp. 891-901 (2015)

Tanabe A, Hibi T, Matsumoto K, Yokoyama M, Kurihara M, Ipponjima S, Hashimoto N, Nemoto T.
Transmissive liquid crystal devices correcting the spherical aberrations in laser scanning microscopy
Proc. SPIE Bios. p. 9335-1,(2015) doi:10.1117/12.2076342

Yuka Aoyagi, Ryosuke Kawakami, Hisayuki Osanai, Terumasa Hibi, Tomomi Nemoto
A Rapid Optical Clearing Protocol using 2,2-Thiodiethanol for Microscopic Observation of Fixed Mouse Brain”,
PLoS ONE 10(1): e0116280. doi:10.1371/journal.pone.0116280　被引用回数トップ25% (207.7.4)

M. Nakao, S. Takemoto, T. Sugiura, K. Sawada, R. Kawakami, T. Nemoto and T. Matsuda
"Interactive Visual Exploration of Overlapping Similar Structures for Three-dimensional Microscope Images",
BMC Bioinformatics 15(1):415. (2015) doi: 10.1186/s12859-014-0415-x

2014

Megumi Nakao*†, Shintaro Takemoto†, Tadao Sugiura†, Kazuaki Sawada†, Ryosuke Kawakami†, Tomomi Nemoto† and Tetsuya Matsuda
"Interactive Visual Exploration of Overlapping Similar Structures for Three-dimensional Microscope Images" BMC Bioinformatics vol. 15, article# 415 (2014) doi:10.1186/s12859-014-0415-x

Yuka Aoyagi, Ryosuke Kawakami, Hisayuki Osanai, Terumasa Hibi, Tomomi Nemoto
“A Rapid Optical Clearing Protocol using 2,2’-Thiodiethanol for Microscopic Observation of Fixed Mouse Brain” PLoS ONE vol. 10, No. 1, Article#: e0116280. e0116280-1 - e0116280-13 doi:10.1371/journal.pone.0116280

Kohei Otomo†, Terumasa Hibi†, Yuichi Kozawa,Makoto Kurihara,Nobuyuki Hashimoto, Hiroyuki Yokoyama,Shunichi Sato, Tomomi Nemoto*
“Two-Photon Excitation STED Microscopy by Utilizing Transmissive Liquid Crystal Devices” Optics Expressvol. 22, No, 23, pp. 28215-28221 (2014) †equally contributed

Tomomi Nemoto
“Development of novel two-photon microscopy for living brain and neuron” Microscopy vol. 63 (suppl 1), pp. i7-i8 (2014) doi: 10.1093/jmicro/dfu087

Yusuke Oshima, Takaeshi Imamura, Atsuko Shintani, Hiroko Kajiura-Kobayashi, Terumasa Hibi, Takeharu Nagai, shigenori Nonaka, Tomomi Nemoto
“Ultrasensitive imaging of Ca2+ dynamics in pancreatic acinar cells of Yellow Cameleon-Nano transgenic mice” Int. J. Mol. Sci. vol. 15, No. 11, pp: 19971-86.

Megumi Nakao, Kosuke Kurebayashi, Tadao Sugiura, Tetsuo Sato, Kazuaki Sawada, Ryosuke Kawakami, Tomomi Nemoto, Kotaro Minato, Tetsuya Matsuda
“Visualizing in vivo Brain Neural Structures Using Volume Rendered Feature Spaces” Computers in Biology and Medicine vol. 53, pp. 85-93. (2014) doi: 10.1016/j.compbiomed.2014.07.007

Satoshi Asano, Tomomi Nemoto, Tomoya Kitayama, Kae Harada, Jun Zhang, Kana Harada, Isei Tanida, Masato Hirata, and Takashi, Kanematsu
“Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretion” Biology Open vol. 3, No. 6, pp. 463-474. (2014) doi: 10.1242/bio.20147591

Yuta Kusama,Yuichiro Tanushi,Masami Yokoyama,Ryosuke Kawakami,Terumasa Hibi,Yuichi Kozawa,Tomomi Nemoto,Shunichi Sato,and Hiroyuki Yokoyama*
“7-ps optical pulse generation from a 1064-nm gain-switched laser diode and its application for two-photon microscopy”
Optics Express, vol. 22, No. 5, pp. 5746-5753 (2014) doi: 10.1364/OE.22.005746

Sari Ipponjima, Terumasa Hibi, Yuichi Kozawa, Hibiki Horanai, Hiroyuki Yokoyama, Shunichi Sato, Tomomi Nemoto
"Improvement of lateral resolution and extension of depth of field in two-photon microscopy by a higher-order radially polarized beam"
Microscopy, vol. 63, No. 1, pp. 23-32. (2014) doi: 10.1093/jmicro/dft041

Daisuke Takao, Tomomi Nemoto, Takaya Abe, Hiroshi Kiyonari, Hiroko Kajiura-Kobayashi, Hidetaka Shiratori, Shigenori Nonaka
”Asymmetric distribution of dynamic calcium signals in the node of mouse embryo during left–right axis formation”
Developmental Biol, vol. 376, No.1, pp. 23-30. (2013) doi: 10.1016/j.ydbio.2013.01.018

Ryosuke Kawakami, Kazuaki Sawada, Aya Sato, Terumasa Hibi, Yuichi　Kozawa, Shunichi Sato, Hiroyuki Yokoyama, and Tomomi Nemoto
"Visualizing hippocampal neurons with in vivo two-photon microscopy　using a 1030 nm picosecond pulse laser"
Scientific Rep., vol. 3, Article #1014. pp: 1014-1 – 1014-7(2013) doi:10.1038/srep01014

Sho Ogata, Takashi Miki, Susumu Seino, Seiichi Tamai, Haruo Kasai, Tomomi Nemoto
”A Novel Function of Noc2 in Agonist-Induced Intracellular Ca2+ Increase during Zymogen-Granule Exocytosis in Pancreatic Acinar Cells”
PLoS ONE, 7(5): e37048. doi:10.1371/journal.pone.0037048

Ayano Tanabe, Yuka Saito, Makoto Kurihara, Nobuyuki Hashimoto,Yuichi Kozawa, Shunichi Sato, Terumasa Hibi, Tomomi Nemoto
“Observation of PDLCs by SHG laser scanning microscopy using a liquid crystal vector beam generator”
Proc SPIE, p. 8279-20 (2012) doi:10.1117/12.907076

Hiroyuki Inada, Miho Watanabe, Taku Uchida, Hitoshi Ishibashi, Hiroaki Wake, Tomomi Nemoto, Yuchio Yanagawa, Atsuo Fukuda, Junichi Nabekura
“GABA regulates the multidirectional tangential migration of GABAergic interneurons in living neonatal mice”
PLoS ONE, Vol. 6, No. 12, e27048 (epub)(2011) doi：10.1371/journal.pone.0027048

Yuichi Kozawa†, Terumasa Hibi†, Aya Sato, Hibiki Horanai, Makoto Kurihara, Nobuyuki Hashimoto, Hiroyuki Yokoyama, Tomomi Nemoto, and Shunichi Sato (†: equally contributed)
"Lateral resolution enhancement of laser scanning microscopy by higher-order radially polarized mode beam"
Optics Express, Vol. 19, Issue 17, pp. 15947-15954 (2011) doi: 10.1364/OE.19.015947

Masato Sawada, Naoko Kaneko, Hiroyuki Inada, Hiroaki Wake, Yasuko Kato, Yuchio Yanagawa, Kazuto Kobayashi, Tomomi Nemoto, Junichi Nabekura, and Kazunobu Sawamoto
"Sensory input regulates spatial and subtype-specific patterns of neuronal turnover in the adult olfactory bulb"
J. Neurosci., vol.31, pp. 11587-11596 (2011) doi: 10.1523/JNEUROSCI.0614-11.2011

Yukihiko Ebisuno, Koko Katagiri, Tomoya Katakai, Yoshihiro Ueda, Tomomi Nemoto, Hiroyuki Inada, Junichi Nabekura, Takaharu Okada, Reiji Kannagi, Toshiyuki Tanaka, Masayuki Miyasaka, Nancy Hogg,* Tatsuo Kinashi
“Rap1 controls lymphocyte adhesion cascade and interstitial migration within lymph nodes in a RAPL-dependent and -independent manners”
Blood, 115(4):804-14 (2010) doi:10.1182/blood-2009-03-211979

Tomomi Nemoto
"Potential of “in vivo” Two-photon microscopy in visualization of 3D structure and functional information in living body”
J. Pharmacolog. Sci., vol.112, p. 45P (2010)

Tomomi Nemoto
“Two-photon microscopic analysis of sequential compound exocytosis”
J. Phyisiol. Sci., vol. 60, p. S45-S45 (2010)

Naoto Matsuda, Hui Lu, Yuko Fukata, Jun Noritake, Hongfeng Gao, Sujay Mukherjee, Tomomi Nemoto, Masaki Fukata, Mu-ming Poo
“Differential Activity-Dependent Secretion of Brain-Derived Neurotrophic Factor from Axon and Dendrite”
J. Neurosci., 29(45), 14185-98 (2009)

Eriko Ohta, Tomohiro Itoh, Tomomi Nemoto, Jiro Kumagai, Shigeru B.H. Ko, Kenichi Ishibashi, Mayuko Ohno, Keiko Uchida, Akihito Ohta, Eisei Sohara, Shinichi Uchida, Sei Sasaki, *Tatemitsu Rai
“Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis”
Am. J. Physiol. Cell Physiol., 297(6):C1368-78 (2009) doi: 10.1152/ajpcell.00117.2009

Yusuke Takatsuru, Dai Fukumoto, Miki Yoshitomo, Tomomi Nemoto, Hideo Tsukada, *Junichi Nabekura
“Neuronal circuit remodeling in the contralateral cortical hemisphere during functional recovery from cerebral infarction”
J. Neurosci., vol.29, pp.10081-6 (2009) doi:10.1523/JNEUROSCI.1638-09.2009

Wataru Tomosugi, Tomoki Matsuda, Tomomi Tani, Ippei Kotera, Kenta Saito, Kazuki Horikagwa, Tomomi Nemoto, and *Takeharu Nagai
“An ultramarine fluorescent protein with high photostability and pH insensitivity”
Nature Methods, vol.6, pp.351-353 (2009) doi: 10.1038/NMETH.1317

Takashi Kanematsu, Tomomi Nemoto, Masato Hirata
“Deficiency of PRIP gene in mice exhibits a phenotype of hyperinsulinemia”
J. Pharmacolog. Sci., vol.111, p. 45P, (2009)

Masato Sawada, Naoko Kaneko, Hiroaki Wake, Hiroyuki Inada, Yasuko Kato, Yuchio Yanagawa, Kazuto Kobayashi, Tomomi Nemoto, Junichi Nabekura, and Kazunobu Sawamoto
“In vivo imaging of sensory input-dependent neurogenesis in the adult olfactory bulb”
Neurosci. Res., vol. 65, p. S54-S54 (2009) doi: 10.1016/j.neures.2009.09.130

Takatsuru Y, Fukumoto D, Yoshitomo M, Nemoto T, Tsukada H, Nabekura J.
“The functional remodeling of contralateral hemisphere during the recovery from the focal infarction in somatosensory cortex”
J. Phyisiol. Sci., vol. 59, p. 372-372 (2009)

Eriko Ohta, Tomohiro Itoh, Tomomi Nemoto, Jiro Kumagai, Shigeru B.H. Ko, Kenichi Ishibashi, Mayuko Ohno, Keiko Uchida, Akihito Ohta, Eisei Sohara, Shinichi Uchida, Sei Sasaki, Tatemitsu Rai
“Pancreas-specific aquaporin12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis”
J. Phyisiol. Sci., vol. 59, p. 399-399 (2009)

Takashi Kanematsu, Tomomi Nemoto, Masato Hirata Masato
“PRIP-KO mice exhibit a phenotype of hyperinsulinemia”
J. Pharmocolg. Sci., vol. 109 p. 92P-92P (2009)

2008

Tomomi Nemoto
“Principle and potential of two-photon microscopy”
Neurosci. Res.vol. 61, p. S27-S27 (2008)

2007

*Chiming Wei, Takeharu Nagai, Wenchi Wei, Tomomi Nemoto, Muhammad Awais, Osamu Niwa, Ryoji Kurita, Yashinobu Baba
“New advances in Nanomedicine: Diagnosis and Preventive Medicine”
Med. Clin. N. Am., vol.91, pp.871-879 (2007) doi: 10.1016/j.mcna.2007.05.002

Hiroaki Wake, Tomomi Nemoto, and Junichi Nabekura,
“Long term observation of fine structural plasticity of neurons and glias in damaged cerebral cortex of living mice”
Neurosci. Res., vol. 58, p. S12-S12 (2007) doi: 10.1016/j.neures.2007.06.070

2006

*Haruo Kasai, Takuya Kishimoto , Tomomi Nemoto , Hiroyasu Hatakeyama , Ting-Ting Liu , Noriko Takahashi
“Two-photon excitation imaging of exocytosis and endocytosis and their spatial organizations”
Adv. Drug Deliv. Rev., vol.58, pp.850-77 (2006) doi: 10.1016/j.addr.2006.07.008

Takuya Kishimoto, Ryoichi Kimura, Ting-Ting Liu, Tomomi Nemoto, Noriko Takahashi and *Haruo Kasai
“Vacuolar sequential exocytosis of large dense-core vesicles in adrenal medulla”
EMBO J., vol.25, pp.673-82 (2006) doi: 10.1038/sj.emboj.7600983

Hiroyasu Hatakeyama, Takuya Kishimoto, Tomomi Nemoto, Haruo Kasai and *Noriko Takahashi
“Rapid glucose sensing by protein kinase A for insulin exocytosis in mouse pancreatic islets”
J. Physiol., vol.570, pp.271-282 (2006) DOI: 10.1113/jphysiol.2005.096560

2005

Ting-ting Liu, Takuya Kishimoto, Hiroyasu Hatakeyam, Tomomi Nemoto, Noriko Takahashi, *Haruo Kasai
“Exocytosis and endocytosis of small vesicles in PC12 cells studied with TEPIQ (two-photon extracellular polar-tracer imaging-based quantification) analysis”
J. Physiol., vol. 568, pp. 917-29 (2005) DOI: 10.1113/jphysiol.2005.094011

Takuya Kishimoto, Ting-ting Liu, Hiroyasu Hatakeyama, Tomomi Nemoto, Noriko Takahashi, *Haruo Kasai
“Sequential compound exocytosis of large dense-core vesicles in PC12 cells studied with TEPIQ (two-photon extracellular polar-tracer imaging-based quantification) analysis”
J. Physiol., vol.568, pp.905-15 (2005) DOI: 10.1113/jphysiol.2005.094003

Takuya Kishimoto , Ting-ting Liu , Tomomi Nemoto & Noriko Takahashi
“A new quantitative (TEPIQ) analysis for diameters of exocytic vesicles and its application to pancreatic islets”
J. Physiol., vol.568, pp.891-903 (2005) DOI: 10.1113/jphysiol.2005.093047

Akihiro Oshima, Tatsuya Kojima, Kenji Dejima, Yasuo Hisa, Haruo Kasai, and *Tomomi Nemoto
“Two-photon microscopic analysis of acetylcholine-induced mucus secretion in guinea pig nasal glands”
Cell Calcium, vol.37, pp.349-357 (2005) DOI: 10.1016/j.ceca.2004.12.003

Yasuyuki Hayakawa, Tomomi Nemoto, Masamitsu Iino, *Haruo Kasai
“Rapid Ca2+-dependent increase in oxygen consumption by mitochondria in single mammalian central neurons”
Cell Calcium, vol.37, pp.359-370 (2005) DOI: 10.1016/j.ceca.2004.11.005

2004

Tomomi Nemoto, Tatsuya Kojima, Akihiro Oshima, Haruhiko Bito and Haruo Kasai
“Stabilization of exocytosis by dynamic F-actin coating of zymogen granules in pancreatic acini”
Biol. Chem., vol.279, pp.37544-37550 (2004)

2003

Takahashi, N., Kishimoto, T., Nemoto, T., Kasai, H.
“Two-photon imaging of insulin exocytosis in the pancreatic islets”
J. Pharmacolog. Sci., vol.91, pp.32P-32P (Suppl.), (2003)

2002

Noriko Takahashi, Takuya Kishimoto, Tomomi Nemoto, Takashi Kadowaki, *Haruo Kasai
“Fusion pore dynamics and insulin granule exocytosis in the pancreatic islet”
Science, vol.297, pp.1349-52 (2002) DOI:10.1126/science.1073806

Mitsuhiko Noda, Shigeo Yamashita, Noriko Takahashi, Kazuhiro Eto, Linming Shen, Kazuo Izumi, Samira Daniel, Yoshiharu Tsubamoto, Tomomi Nemoto, Masamitsu Iino, Haruo Kasai, Geoffrey W.G. Sharp, and *Takashi Kadowaki
“Switch to anaerobic glucose metabolism with NADH accumulation in the ß-cell model of mitochondrial diabetes: Characteristics of ßHC9 cells deficient in mitochondrial DNA transcription”
J. Biol. Chem. DOI: 10.1074/jbc.M207690200

Tomomi Nemoto, Ryoichi Kimura, Akira Tachikawa, Akiko Miwa, Haruo Okado, Yasushi Miyashita, Masamitsu Iino, Takashi Kadowaki and Haruo Kasai
“Two-photon excitation imaging of pancreatic islet with various fluorescent probes.”
Diabetesvol.S1, pp.25-28 (2002) DOI: 10.2337/diabetes.51.2007.S25

2001

Tomomi Nemoto, Ryoichi Kimura, Koichi Ito, Akira Tachikawa, Yasushi Miyashita, Masamitsu Iino, and *Haruo Kasai
“Sequential Replenishment Mechanism of Exocytosis in Pancreatic Acini”
Nature Cell Biol.vol.3, pp.253-258 (2001) DOI: 10.1038/35060042

Masanori Matsuzaki, Graham C. R. Ellis-Davies, Tomomi Nemoto, Yasushi Miyashita, Masamitsu Iino, *Haruo Kasai
“Dendritic spine geometry is ciritical for functional AMPA receptor expression in hippocampal CA1 pyramidal neurons”
Nature Neurosci.vol.4, No.11, pp.1086-1092 (2001) DOI: 10.1038/nn736

Noriko Takahashi, Tomomi Nemoto , Haruo Kasai
“Two-photon excitation imaging of insulin exocytosis from intact pancreatic islet of Langerhans”
DIABETOLOGIAvol.44, p.231 (2001)

1998

Go Uchida, Yuuki Mizukami, Tomomi Nemoto, Yoshimi Tsuchiya
“Sliding Motion of Magnetizable Beads Coated with Chara Motor Protein in a Magnetic Field”
J. Phys. Soc. Jpn., vol. 67, pp. 345-350 (1998)

1995

Tomomi Nemoto, Go Uchida, Atsuko Takamatsu, Yoshimi Tsuchiya
“Stochastic Behaviors of Organelle Motion in Nitella Internodal Cells”
Biochem. Biophys. Res. Comm., vol.214, No.3, pp.1102-1107 (1995) DOI: 10.1006/bbrc.1995.2399

Go Uchida, Tomomi Nemoto, Yoshimi Tsuchiya
“Characteristics of Sliding Motions of Small Organelles in a Nitella Internodal Cell
J. Phys. Soc. Jpn., vol.64, No.12, pp.4959-4963 (1995) DOI: 10.1143/JPSJ.64.4959