Takemura Lab Seminar: Mauro Costagli (University of Genoa, Italy)
Date & Time
March 28th (Thursday), 2024
11:00-12:00
Venue
Myodaiji Area Seminar Room A/B, National Institute for Physiological Sciences
Registration
Co-host
Frontiers of Life Sciences [Spin-L]
Language
English
Speaker
Mauro Costagli (Associate Professor of Applied Medical Technical Sciences at University of Genoa, Italy / Visiting Scientist at RIKEN Center for Brain Sciences, Wakoshi, Japan)
Title and abstract
Title: Quantitative Susceptibility Mapping: a tool to investigate brain anatomy and function with Magnetic Resonance Imaging
Abstract: Quantitative Susceptibility Mapping (QSM) is a recently established MRI-based technique allowing the non-invasive assessment of magnetic susceptibility of biological tissues. In brain imaging, QSM is used not only to enrich anatomical neuroimaging - principally via the assessment of tissue iron content and myelination - but also to support functional neuroimaging (fMRI) by providing a measure of magnetic properties of venous blood susceptibility dynamics, dependent on the varying balance between oxygenated and deoxygenated hemoglobin in response to neuronal activity. This seminar will guide the attendees from basic, conventional MRI based on Gradient-Recalled Echo (GRE), through all the aspects that enable improved qualitative susceptibility weighted imaging and quantitative susceptibility mapping in the brain. Representative applications in clinical brain research and neuroscience will be illustrated. The most up-to-date consensus recommendations of the International QSM community for implementing susceptibility mapping in brain research will also be illustrated, highlighting this technique's potentiality and limitations.
*This seminar is supported by the Japanese Society for the Promotion of Science.