Takemura Lab Seminar: Mauro Costagli (University of Genoa, Italy)
日時
2024年3月28日（木） 11:00-12:00
会場
オンサイト: 生理学研究所明大寺地区セミナー室A/B
参加登録
共催
共同利用・共同研究システム形成事業 「学際領域展開ハブ形成プログラム」【スピン生命フロンティア (Spin-L)】
使用言語
英語
演者
Mauro Costagli (Associate Professor of Applied Medical Technical Sciences at University of Genoa, Italy / Visiting Scientist at RIKEN Center for Brain Sciences, Wakoshi, Japan)
タイトル・抄録
Title: Quantitative Susceptibility Mapping: a tool to investigate brain anatomy and function with Magnetic Resonance Imaging
Abstract: Quantitative Susceptibility Mapping (QSM) is a recently established MRI-based technique allowing the non-invasive assessment of magnetic susceptibility of biological tissues. In brain imaging, QSM is used not only to enrich anatomical neuroimaging - principally via the assessment of tissue iron content and myelination - but also to support functional neuroimaging (fMRI) by providing a measure of magnetic properties of venous blood susceptibility dynamics, dependent on the varying balance between oxygenated and deoxygenated hemoglobin in response to neuronal activity. This seminar will guide the attendees from basic, conventional MRI based on Gradient-Recalled Echo (GRE), through all the aspects that enable improved qualitative susceptibility weighted imaging and quantitative susceptibility mapping in the brain. Representative applications in clinical brain research and neuroscience will be illustrated. The most up-to-date consensus recommendations of the International QSM community for implementing susceptibility mapping in brain research will also be illustrated, highlighting this technique's potentiality and limitations.
*This seminar is supported by the Japanese Society for the Promotion of Science.