生理学研究所 総合生理研究系 生体システム研究部門

業績Publications

  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010
  • 2009
  • 2008
  • 2007
  • 2006
  • 2005
  • 2004
  • 2003
  • 2002

2018

Original paper
Wakabayashi M, Koketsu D, Kondo H, Sato S, Ohara K, Polyakova Z, Chiken S, Hatanaka N, Nambu A (2018) Development of stereotaxic recording system for awake marmosets (Callithrix jacchus). Neurosci Res (in press) doi: 10.1016/j.neures.2018.01.001
Ebina T, Masamizu Y, Tanaka YR, Watakabe A, Hirakawa R, Hirayama Y, Hira R, Terada S, Koketsu D, Hikosaka K, Mizukami H, Nambu A, Sasaki E, Yamamori Y, Matsuzaki M (2018) Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks. Nat Neurosci (in press) DOI: 10.1038/s41467-018-04286-6
Endo K, Ishigaki S, Masamizu Y, Fujioka Y, Watakabe A, Yamamori T, Hatanaka N, Nambu A, Okado H, Katsuno M, Watanabe H, Matsuzaki M, Sobue G (2018) Silencing of FUS in the common marmoset (Callithrix jacchus) brainvia stereotaxic injection of an adeno-associated virus encoding shRNA. Neurosci Res 130: 56-64. doi: 10.1016/j.neures.2017.08.006

2017

Original paper
Ozaki M, Sano H, Sato S, Ogura M, Mushiake H, Chiken S, Nakao N, Nambu A (2017) Optogenetic activation of the sensorimotor cortex reveals “local inhibitory and global excitatory” inputs to the basal ganglia. Cerebral Cortex 27: 5716-5726. doi: 10.1093/cercor/bhx234
大脳皮質から大脳基底核へ情報が伝わる様子を、光を使って解明
-『必要な運動を引き起こし、不要な運動を抑制する』しくみ-
Iwamuro H, Tachibana Y, Ugawa Y, Saito N, Nambu A (2017) Information processing from the motor cortices to the subthalamic nucleus and globus pallidus and their somatotopic organizations revealed electrophysiologically in monkeys. Eur J Neurosci 46: 2684-2701. DOI: 10.1111/ejn.13738
Shouno O, Tachibana Y, Nambu A, Doya K (2017) Computational Model of Recurrent Subthalamo-Pallidal Circuit for Generation of Parkinsonian Oscillations. Front. Neuroanat. 11:21. doi: 10.3389/fnana.2017.00021
Baladron J, Nambu A, Hamker F (2017) The subthalamic nucleus-external globus pallidus loop biases exploratory decisions towards known alternatives: a neuro-computational study. Eur J Neurosci (in press) DOI: 10.1111/ejn.13666
Bouchekioua Y, Tsutsui-Kimura I, Sano H, Koizumi M, Tanaka KF, Yoshida K, Kosaki Y, Watanabe S, Mimura M (2017) Striatonigral direct pathway activation is sufficient to induce repetitive behaviors. Neurosci Res (in press) doi: 10.1016/j.neures.2017.09.007.
Tsutsui-Kimura I, Takiue H, Yoshida K, Xu M, Yano R, Ohta H, Nishida H, Bouchekioua Y, Okano H, Uchigashima M, Watanabe M, Takata N, Drew MR, Sano H, Mimura M, Tanaka KF (2017) Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation. Nat Commun 8:14304. doi: 10.1038/ncomms14304.
Osanai Y, Shimizu T, Mori T, Yoshimura Y, Hatanaka N, Nambu A, Kimori Y, Koyama S, Kobayashi K, Ikenaka K (2017) Rabies virus-mediated oligodendrocyte labeling reveals a single oligodendrocyte myelinates axons from distinct brain regions. Glia 65: 93-105. doi: 10.1002/glia.23076.
Taruno A, Kashio M, Sun H, Kobayashi K, Sano H, Nambu A, Marunaka Y (2017) Adeno-associated virus-mediated gene transfer into taste cells in vivo. Chemical Senses 42: 69-78. doi:10.1093/chemse/bjw10
Review in Japanese
知見 聡美、南部 篤 (2017) 脳深部刺激療法(DBS)の作用機.Frontiers in Parkinson Disease 10: 86-89.
南部 篤(2017)大脳皮質—大脳基底核ループとその機能. Clinical Neuroscience 35: 43-47

2016

Original paper
Horie M, Mekada K, Sano H, Kikkawa Y, Chiken S, Someya T, Saito K, Hossain MD, Nameta M, Abe K, Sakimura K, Ono K, Nambu A, Yoshiki A, Takebayashi H (2016) Characterization of novel dystonia musculorum mutant mice: implications for central nervous system abnormality. Neurobiol Dis 96: 271-283. doi: 10.1016/j.nbd.2016.09.016
Darbin O, Jin X, Von Wrangel C, Schwabe K, Nambu A, Naritoku DK, Krauss JK, Alam M (2016) Neuronal Entropy-Rate Feature of Entopeduncular Nucleus in Rat Model of Parkinson's Disease. Int J Neural Syst 26: 1550038. doi: 10.1142/S0129065715500380
Kobayashi K, Sano H, Kato S, Kuroda K, Nakamuta S, Isa T, Nambu A, Kaibuchi K, Kobayashi K (2016) Survival of corticostriatal neurons by Rho/Rho-kinase signaling pathway. Neurosci Lett 630: 45-52. doi: 10.1016/j.neulet.2016.07.020.
Reviews
Chiken S, Nambu A (2016) Mechanism of Deep Brain Stimulation: Inhibition, Excitation or Disruption? The Neuroscientist 22: 313-322. doi: 10.1177/1073858415581986
Review in Japanese
南部 篤、知見 聡美 (2016) DBSのメカニズム.Clinical Neuroscience 34: 201-214.

2015

Original paper
Chiken S, Sato A, Ohta C, Kurokawa M, Arai S, Maeshima J, Sunayama-Morita T, Sasaoka T, Nambu A (2015) Dopamine D1 receptor-mediated transmission maintains information flow through the cortico-striato-entopeduncular direct pathway to release movements. Cerebral Cortex 25: 4885-4897. doi: 10.1093/cercor/bhv209
ドーパミン神経伝達は、大脳基底核における運動情報伝達と、運動発現に不可欠
Sano H, Murata H, Nambu A (2015) Zonisamide reduces nigrostriatal dopaminergic neurodegeneration in a mouse genetic model of Parkinson's disease. J Neurochemi 134: 371-381
Reviews
Nambu A, Tachibana Y, Chiken S (2015) Cause of parkinsonian symptoms: Firing rate, firing pattern or dynamic activity changes? Basal Ganglia 5(1):1-6 doi: 10.1016/j.baga.2014.11.001
Book chapter in Japanese
南部 篤(2015)大脳基底核の機能解剖. 橋本信夫(監)「脳神経外科プラクティス 6, 脳神経外科医が知っておくべきニューロサイエンスの知識」文光堂 pp75-76
知見 聡美、南部 篤(2015)視床の機能解剖.橋本信夫(監)「脳神経外科プラクティス 6, 脳神経外科医が知っておくべきニューロサイエンスの知識」文光堂 pp 77-78.
佐野裕美、小林和人、南部 篤(2015)大脳基底核による運動制御と病態生理.三品昌美編「分子脳科学:分子から脳機能と心に迫る」 化学同人 pp44-55
南部 篤(2015)強化学習. 里宇明元、牛場潤一(監)神経科学の最前線とリハビリテーション:脳の可塑性と運動. 医歯薬出版 pp31-36

2014

Original paper
Horie M, Watanabe K, Bepari AK, Nashimoto J, Araki K, Sano H, Chiken S, Nambu A, Ono K, Ikenaka K, Kakita A, Yamamura K, Takebayashi H (2014) Disruption of actin-binding domain-containing Dystonin protein causes dystonia musculorum in mice. Eur J Neurosci 40: 3458-3471. DOI: 10.1111/ejn.12711
Reviews
Chiken S, Nambu A (2014) Disrupting neuronal transmission: mechanism of DBS? Front Syst Neurosci 8:33. doi: 10.3389/fnsys.2014.00033
Nambu A, Tachibana Y (2014) Mechanism of parkinsonian neuronal oscillations in the primate basal ganglia: some considerations based on our recent work. Front Syst Neurosci 8:74 doi: 10.3389/fnsys.2014.00074
Book chapter
Nambu A (2014) Functional circuitry of the basal ganglia. Deep Brain Stimulation for Neurological Disorders. Ed. Itakura T, Springer, pp1-11
Nambu A, Chiken S (2014) Mechanism of DBS: Inhibition, Excitation, or Disruption? Deep Brain Stimulation for Neurological Disorders. Ed. Itakura T, Springer, pp13-20
Review in Japanese
橘 吉寿、彦坂 興秀、南部 篤 (2014) 大脳基底核の神経回路と行動選択. Clinical Neuroscience 32: 33-35
佐野 裕美、南部 篤 (2014) 無動、寡動、舞踏運動の病態生理. Clinical Neuroscience 32: 80-82
南部 篤、橘 吉寿 (2014) パーキンソン病と脳のオシレーション. Clinical Neuroscience 32: 768-771
Book chapter in Japanese
南部 篤(2014)大脳皮質と大脳基底核. 標準生理学第8版, 医学書院, pp 342-366
南部 篤(2014)大脳基底核. カンデル神経科学(訳書), メディカル•サイエンス•インターナショナル, pp 963-978

2013

Original paper
Chiken S, Nambu A (2013) High-frequency pallidal stimulation disrupts information flow through the pallidum by GABAergic inhibition. J Neurosci 33: 2268-2280. doi: 10.1523/JNEUROSCI.4144-11.2013.
Sano H, Chiken S, Hikida T, Kobayashi K, Nambu A (2013) Signals through the striatopallidal indirect pathway stop movements by phasic excitation in the substantia nigra. J Neurosci 33: 7583-7594. doi: 10.1523/JNEUROSCI.4932-12.2013.
Sotoyama H, Namba H, Chiken S, Nambu A, Nawa H (2013) Exposure to the cytokine EGF leads to abnormal hyperactivity of pallidal GABA neurons: implications for schizophrenia and its modeling. J Neurochemi 126: 518-528. doi: 10.1111/jnc.12223.
Chen S, Shin D, Watanabe H, Nakanishi Y, Kambara H, Yoshimura N, Nambu A, Isa T, Nishimura Y, Koike Y (2013) Prediction of hand trajectory from electrocorticography signals in primary motor cortex. PLoS One 8(12): e83534. DOI: 10.1371/journal.pone.0083534
Miyachi S, Hirata Y, Inoue K, Lu X, Nambu A, Takada M (2013) Multisynaptic projections from the ventrolateral prefrontal cortex to hand and mouth representations of the monkey primary motor cortex. Neurosci Res 76:141-149. DOI: 10.1016/j.neures.2013.04.004
Reviews
Obeso JA, Guridi J, Nambu A, Crossman A (2013) Motor manifestations and basal ganglia output activity: the paradox continues. Mov Disord 28: 416-418. doi: 10.1002/mds.25358
Takada M, Hoshi E, Saga Y, Inoue KI, Miyachi S, Hatanaka N, Inase M, Nambu A (2013) Organization of two cortico–basal ganglia loop circuits that arise from distinct sectors of the monkey dorsal premotor cortex. Basal Ganglia – An Integrative View. DOI: 10.5772/54822
Takada M, Inoue K, Koketsu D, Kato S, Kobayashi K, Nambu A (2013) Elucidating information processing in primate basal ganglia circuitry: a novel technique for pathway-selective ablation mediated by immunotoxin. Front Neural Circuits 7: 140. doi: 10.3389/fncir.2013.00140
Review in Japanese
南部 篤 (2013) 大脳基底核. 藤永保 (監修) 最新心理学事典 平凡社, pp492-494
南部 篤 (2013) 大脳基底核疾患の病態生理. 辻省次、高橋良輔 (編) パーキンソン病と運動異常 中山書店, pp12-20

2012

Original paper
Inoue KI, Koketsu D, Kato S, Kobayashi K, Nambu A, Takada M (2012) Immunotoxin-mediated tract targeting in the primate brain: selective elimination of the cortico-subthalamic "hyperdirect" pathway. PLoS ONE 7(6): e39149
Takahara D, Inoue KI, Hirata Y, Miyachi S, Nambu A, Takada M, Hoshi E (2012) Multisynaptic projections from the ventrolateral prefrontal cortex to the dorsal premotor cortex in macaques - anatomical substrate for conditional visuomotor behavior. Eur J Neurosci 36: 3365-3375
Shin D, Watanabe H, Kambara H, Nambu A, Isa T, Nishimura Y, Koike Y (2012) Prediction of muscle activities from electrocorticograms in primary motor cortex of primates. PLoS ONE 7(10): e47992
Watanabe H, Sato M, Suzuki T, Nambu A, Nishimura Y, Kawato M, Isa T (2012) Reconstruction of movement-related intracortical activity from micro-electrocorticogram array signals in monkey primary motor cortex. J Neural Eng 9:036006
Bepari AK, Sano H, Tamamaki N, Nambu A, Tanaka KF, Takebayashi H (2012) Identification of optogenetically activated striatal medium spiny neurons by Npas4 expression. PLoS ONE 7(12): e52783 DOI: 10.1371/journal.pone.0052783
Reviews
Nambu A (2012) GABA-B receptor: possible target for Parkinson's disease therapy. Exp Neurol 233: 121-122
Book chapter
Nambu A (2012) Dystonia. Neuroscience in the 21st Century. Eds Pfaff, Springer, vol 2: pp1143-1148
Review in Japanese
南部 篤 (2012) 大脳基底核疾患の病態生理. 臨床神経学 52:1198-1200
知見 聡美、南部 篤 (2012) 大脳基底核の運動制御における抑制性ニューロン. Clinical Neuroscience 30: 1381-1384
Book chapter in Japanese
南部 篤 (2012) モデルマウスの神経活動からジストニアの病態を考える. 長谷川一子 (編) ジストニア2012 中外医学社, pp194-202

2011

Original paper
Saga Y, Hirata Y, Takahara D, Inoue K, Miyachi S, Nambu A, Tanji J, Takada M, Hoshi E (2011) Origins of multisynaptic projections from the basal ganglia to rostrocaudally distinct sectors of the dorsal premotor area in macaques. Eur J Neurosci 33: 285-297
Nishibayashi H, Ogura M, Kakishita K, Tanaka S, Tachibana Y, Nambu A, Kita K, Itakura T (2011) Cortically evoked responses of human pallidal neurons recorded during stereotactic neurosurgery. Mov Disord 26: 469-476
Yumoto N, Lu X, Henry TR, Miyachi S, Nambu A, Fukai T, Takada M (2011) A neural correlate of the processing of multi-second time intervals in primate prefrontal cortex. PLoS ONE 6(4): e19168.
Takara S, Hatanaka N, Takada M, Nambu A (2011) Differential activity patterns of putaminal neurons with inputs from the primary motor cortex and supplementary motor area in behaving monkeys. J Neurophysiol 106: 1203-1217
Nishibayashi H, Nambu A, Tachibana Y, Itakura T (2011) Re; Cortically evoked responses of human pallidal neurons. Mov Disord 26: 2583-2584
Tachibana Y, Iwamuro H, Kita H, Takada M, Nambu A (2011) Subthalamo-pallidal interactions underlying parkinsonian neuronal oscillations in the primate basal ganglia. Eur J Neurosci 34: 1470-1484
Reviews
Nambu A (2011) Somatotopic organization of the primate basal ganglia. Front Neuroanat 5: 26
Nambu A, Chiken S, Shashidharan P, Nishibayashi H, Ogura M, Kakishita K, Tanaka S, Tachibana Y, Kita H, Itakura T (2011) Reduced pallidal output causes dystonia. Front Syst Neurosci 5: 89
Review in Japanese
南部 篤 (2011) 線条体における運動手続き記憶. Clinical Neuroscience 29: 172-176
南部 篤 (2011) 臨床に役立つ大脳基底核の解剖と生理. 神経治療学 28: 19-23
南部 篤 (2011) 大脳基底核における可塑性. Clinical Neuroscience 29: 782-786
南部 篤 (2011) 気になる脳部位 視床下核. 分子精神医学 11: 203-206

2010

Original paper
Hashimoto M, Takahara D, Hirata Y, Inoue KI, Miyachi S, Nambu A, Tanji J, Takada M, Hoshi E (2010) Motor and non-motor projections from the cerebellum to rostrocaudally distinct sectors of the dorsal premotor cortex in macaques. Eur J Neurosci 31: 1402-1413

2009

Original paper
Hatanaka N, Tokuno H, Nambu A, Takada M (2009) Transdural doppler ultrasonography monitors cerebral blood flow changes in relation to motor tasks. Cereb Cortex 19: 820-831.
Book Chapters
Nambu A (2009) Basal ganglia: physiological circuits. In: Squire LR (ed.) Encyclopedia of Neuroscience, volume 2, pp. 111-117. Oxford: Academic Press.
Nambu A (2009) Dynamic model of the basal ganglia functions and movement disorders. In: Nakanish S, Kageyama R, Watababe D (eds.) Systems Biology: The Challenge of Complexity, pp. 91-97. Springer, Tokyo
Nambu A, Hatanaka N, Takara S, Tachibana Y, Takada M (2009) Information processing in the striatum of behaving monkeys. The Basal Ganglia IX. Eds Groenewegen HJ, Voorn P, Berendse HW, Mulder AB, Cools AR, Springer, pp41-48
Iwamuro H, Tachibana Y, Sato N, Nambu A (2009) Organization of motor cortical inputs to the subthalamic nucleus in the monkey. The Basal Ganglia IX. Eds Groenewegen HJ, Voorn P, Berendse HW, Mulder AB, Cools AR, Springer, pp109-117
Takada M, Inoue K, Miyachi S, Okado H, Nambu A (2009) Prevention of calbindin recruitment into nigral dopamine neurons from MPTP-induced degeneration in Macaca fascicularis. The Basal Ganglia IX. Eds Groenewegen HJ, Voorn P, Berendse HW, Mulder AB, Cools AR, Springer, pp377-385
Review in Japanese
南部 篤 (2009) 直接路・間接路・ハイパー直接路の機能. Brain and Nerve 61: 360-372
南部 篤 (2009) 大脳基底核のsomatotopy. Brain and Nerve 61: 1383-1394
南部 篤 (2009) 大脳基底核における興奮性および抑制性アミノ酸による神経伝達. 生体の科学 60: 348-349
南部 篤 (2009) 大脳基底核の機能. Clinical Neuroscience 27: 769-773
知見 聡美、南部 篤 (2010) モデルマウスの神経活動からジストニアの病態を考察する. 実験医学 28(5) 661-666
南部 篤 (2009) 大脳皮質と大脳基底核. 標準生理学第7版 医学書院, pp 354-379

2008

Original paper
Tachibana Y, Kita H, Chiken S, Takada M, Nambu A (2008) Motor cortical control of internal pallidal activity through glutamatergic and GABAergic inputs in awake monkeys. Eur J Neurosci 27: 238-253
Chiken S, Shashidharan P, Nambu A (2008) Cortically evoked long-lasting inhibition of pallidal neurons in a transgenic mouse model of dystonia. J Neurosci 28: 13967-13977
Reviews
Nambu A (2008) Basal ganglia: physiological circuits. New Encyclopedia of Neuroscience

2007

Original paper
Kita H, Chiken S, Tachibana Y, Nambu A (2007) Serotonin modulates pallidal neuronal activity in the awake monkey. J Neurosci 27: 75-83
Lu X, Miyachi S, Ito Y, Nambu A, Takada M (2007) Topographic distribution of output neurons in cerebellar nuclei and cortex to somatotopic map of primary motor cortex. Eur J Neurosci 25: 2374-2382
Kanamatsua T, Otsuki T, Tokuno H, Nambuc A, Takada M, Okamoto K, Watanabe H, Umeda M, Tsukada Y (2007) Changes in the rates of the tricarboxylic acid (TCA) cycle and glutamine synthesis in the monkey brain with hemiparkinsonism induced by intracarotid infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): Studies by non-invasive 13C-magnetic resonance spectroscopy. Brain Res 1181: 142-148.
Reviews
Nambu A (2007) Globus Pallidus internal segment. GABA and the Basal Ganglia: From Molecules to Systems. Prog Brain Res 160. Eds Tepper JM, Abercrombie ED, Bolam JP, Elsevier, Amsterdam pp135-150
Review in Japanese
南部 篤 (2007) 大脳基底核をめぐる6つの問題 Annual Review神経 15-26
Book chapter in Japanese
南部 篤 (2007) 大脳基底核をめぐる6つの問題 Annual Review神経 15-26
南部 篤 (2007) 脳の損傷・病態モデルによる研究:パーキンソン病を中心に ブレイン・マシン・インターフェース 脳と機械をつなぐ,オーム社 pp126-138
南部 篤 (2007) 大脳基底核の神経回路から大脳基底核疾患の病態を理解する 神経変性疾患のサイエンス 南山堂 pp156-169

2006

Original paper
Kita H, Chiken S, Tachibana Y, Nambu A (2006) Origins of GABAA and GABAB receptor mediated responses of globus pallidus induced after stimulation of the putamen in the monkey. J Neurosci 26: 6554-6562
Miyachi S, Lu X, Imanishi M, Sawada K, Nambu A, Takada M (2006) Somatotopically arranged inputs from putamen and subthalamic nucleus to primary motor cortex. Neurosci Res 56: 300-308
Review in Japanese
南部 篤 (2006) DBSに神経生理学が寄与できること 臨床脳波 48: 327-336
南部 篤 (2006) 人物往来 佐々木和夫 Clinical Neuroscience 24: 608

2005

Original paper
Miyachi S, Lu X, Inoue S, Iwasaki T, Koike S, Nambu A, Takada M (2005) Organization of multisynaptic inputs from prefrontal cortex to primary motor cortex as revealed by retrograde transneuronal transport of rabies virus. J Neurosci 25: 2547-2556
Kita H, Tachibana Y, Nambu A, Chiken S (2005) Balance of monosynaptic excitatory and disynaptic inhibitory responses of the globus pallidus induced after stimulation of the subthalamic nucleus in the monkey. J Neurosci 25: 8611-8619
Kaneda K, Tachibana Y, Imanishi M, Kita H, Shigemoto R, NambuA, Takada M (2005) Downregulation of metabotropic glutamate receptor 1a in globus pallidus and substantia nigra of parkinsonian monkeys. Eur J Neurosci 22: 3241-3254
Hatanaka N, Tokuno H, Nambu A, Inoue T, Takada M (2005) Input-output organization of jaw movement-related areas in monkey frontal cortex. J Comp Neurol 492: 401-425
Reviews
Nambu A (2005) A new approach to understand the pathophysiology of Parkinson's disease. J Neurol 252 [Suppl 4]: 1-4
Book chapter
Nambu A, Tachibana Y, Kaneda K, Tokuno H, Takada M (2005) Dynamic model of basal ganglia functions and parkinson's disease. The Basal Ganglia VIII. Eds Bolam JP, Ingham CA, Magill PJ, Springer pp307-312
Takada M, Kaneda K, Tachibana Y, Imanishi M, Kita H, Shigemoto R, Nambu A (2005) Down regulation of a metabotropic glutamate receptor in the parkinsonian basal ganglia. The Basal Ganglia VIII. Eds Bolam JP, Ingham CA, Magill PJ, Springer pp255-263
Kita H, Tachibana Y, Nambu A (2005) Glutamatergic and GABAergic control of pallidal activity in monkeys. The Basal Ganglia VIII. Eds Bolam JP, Ingham CA, Magill PJ, Springer pp545-554
Book chapter in Japanese
南部 篤 (2005) 大脳皮質と大脳基底核. 標準生理学第6版 医学書院 pp 359-386
南部 篤 (2005) 定位脳手術のための生理学. 定位脳手術入門 医学書院 pp19-33

2004

Original paper
Tachibana Y, Nambu A, Hatanaka N, Miyachi S, Takada M (2004) Input-output organization of the rostral part of the dorsal premotor cortex, with special reference to the corticostriatal projection. Neurosci Res 48: 45-57
Takada M, Nambu A, Hatanaka N, Tachibana Y, Miyachi S, Taira M, Inase M (2004) Organization of prefrontal outflow toward frontal motor-related areas in macaque monkeys. Eur J Neurosci 19: 3328-3342
Kita H, Nambu A, Kaneda K, Tachibana Y, Takada M (2004) Role of ionotropic glutamatergic and GABAergic inputs on the firing activity of neurons in the external pallidum in awake-monkeys. J Neurophysiol 92: 3069-3084
Book Chapter
Nambu A (2004) A New Dynamic Model of Cortico-Basal Ganglia Loop. Brain Mechanisms for the Integration of Posture and Movement. Prog Brain Res 143. eds Mori S, Stuart DG, Wiesendanger M, Elsevier, Amsterdam, pp461-466
Review in Japanese
南部 篤 (2004) 脳深部刺激療法の作用機序 21, 7 262-269
南部 篤 (2004) 定位脳手術のための生理学 脳神経外科 32: 179-191

2003

Original paper
Akazawa T, Takada M, Nambu A (2003) Activity and distribution patterns of monkey pallidal neurons in response to peripheral nerve stimulation. Neurosci Lett 339: 161-165
Fujiwara-Tsukamoto Y, Isomura Y, Nambu A, Takada M (2003) Excitatory GABA input directly drives seizure-like rhythmic synchronization in mature hippocampal CA1 pyramidal cells. Neuroscience 119: 265-275
Kaneda K, Imanishi M, Nambu A, Shigemoto R, Takada M (2003) Differential expression patterns of mGluRIα in monkey nigral dopamine neurons. Neuroscience 14: 947-950
Hatanaka N, Tokuno H, Hamada I, Inase M, Ito Y, Imanishi M, Hasegawa N, Akazawa T, Nambu A, Takada M (2003) Thalamocortical and intracortical connections of monkey cingulate motor areas. J Comp Nerurol 462: 121-138
Isomura Y, Ito Y, Akazawa T, Nambu A, Takada M (2003) Neural coding of "attention for action" and "response selection" in primate anterior cingulated cortex. J Neurosci 23: 8002-8012
Review in Japanese
南部 篤 (2003) 大脳基底核の動的モデルとパーキンソン病 機能的脳神経外科 42: 44-48
金澤 一郎、南部 篤、谷口 真、服部 信孝、村田 美穂、石井 賢二 (2003) パーキンソン病 (座談会) KINESIS 8: 2-18
南部 篤 (2003) 基底核の機能 BRAIN MEDICAL 15: 248-259

2002

Original paper
Isomura Y, Fujiwara-Tsukamoto Y,Imanishi M, Nambu A, Takada M (2002) Distance-dependent Ni2+-sensitivity of synaptic plasticity in apical dendrites of hippocampal CA1pyramidal cells. J Neurophysiol 87: 1169-1174
Kitano K, Cateau H, Kaneda K, Nambu A, Takada M, Fukai T (2002) Two-state membrane potential transitions of striatal spiny neurons as evidenced by numerical simulations and electrophysiological recordings in awake monkeys. J Neurosci
Kaneda K, Nambu A, Tokuno H, Takada M (2002) Differential processing patterns of motor information via striatopallidal and striatonigral projections. J Neurophysiol 88: 1420-1432
Nambu A, Kaneda K, Tokuno H, Takada N (2002) Organization of corticostriatal motor inputs in monkey putamen. J Neurophysiol 88: 1830-1842
Reviews
Nambu A, Tokuno H, Takada M(2002) Functional significance of the cortico-subthalamo-pallidal 'hyperdirect' pathway. Neurosci Res 43: 111-117
Book Chapters
Nambu A, Tokuno H, Hamada I, Kita H, Imanishi M, Akazawa T, Ikeuchi Y, Hasegawa N (2002) Excitatorycortical inputs to pallidal neurons through the cortico-subthalamo-pallidal hyperdirect pathway in the monkey. The Basal GangliaVI. eds Graybiel, DeLong MR, Kitai ST, Kluwer Academic/Plenum Publishers, New York, pp217-223
Takada M, Hamada I, Tokuno H, Inase M Ito Y, Hasegawa N, Ikeuchi Y, Imanishi M, Akazawa T, Hatanaka N, Nambu A (2002) Corticostriatal projections from the cingulate motor areas in the macaque monkey. The Basal Ganglia VI. eds Graybiel, DeLong MR, Kitai ST, Kluwer Academic/Plenum Publishers, New York, pp419-428
Yamaji Y, Matsumura M, Kojima J,Tokuno H, Nambu A, Inase M, Imai H, Takada M (2002) Differential reductions in dopaminergic innervation of the motor-related areas of the frontal lobe in MPTP-treated monkeys. The Basal Ganglia VI. eds Graybiel, DeLong MR, Kitai ST, Kluwer Academic/Plenum Publishers, New York, pp159-167
Nambu A, Kaneda K, Tokuno H, Takada M (2002) Partly converging but largely segregated corticostriatal projections from the primary motor cortex and the supplementary motor area. The Basal Ganglia VII. eds Nicholson LFB, Faul RLM, Kluwer Academic/Plenum Publishers, New York, pp147-153
Takada M, Matsumura M, Kojima J, Yamaji Y, Inase M, Tokuno H, Nambu A, Imai H (2002) Protection against nigrostriatal dopamine cell death by pedunculopontine tegmental nucleus lesions. The Basal Ganglia VII. eds Nicholson LFB, Faul RLM, Kluwer Academic/Plenum Publishers, New York, pp67-76
Review in Japanese
高田 昌彦、南部 篤 (2002) 皮質 - 視床下核投射の機能的意義. 脳の科学 24, 437-444
南部 篤 (2002) 大脳基底核の機能 - パーキンソン病理解のために. 臨床リハ 12: 1095-1101
南部 篤 (2002) 大脳基底核の動的モデルとパーキンソン病. 機能的脳神経外科 41: 98-99

PAGE TOP