業績Publication
2015
- Yatsu R, Miyagawa S, Kohno S, Saito S, Lowers RH, Ogino Y, Fukuta N, Katsu Y, Ohta Y, Tominaga M, Guillette LJ Jr, Iguchi T*.
TRPV4 associates environmental temperature and sex determination in the American alligator.
Sci Rep. 5:18581, 2015, Dec.
PMID:26677944
日本語要旨
- Kim M, Goto T, Yu R, Uchida K, Tominaga M, Kano Y, Takahashi N, Kawada T*.
Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system
Sci Rep. 5:18013, 2015, Dec.
PMID:26673120
- Watanabe M, Suzuki Y*, Uchida K, Miyazaki N, Murata K, Matsumoto S, Kakizaki H, Tominaga M.*
Trpm7 contributes to intercellular junction formation in mouse urothelium.
J Biol Chem. 290(50):29882-29892, 2015,Dec.
PMID:26504086
日本語要旨
- Suzuki N, Mihara H, Nishizono H, Tominaga M, Sugiyama T.
Protease-Activated Receptor-2 Up-Regulates Transient Receptor Potential
Vanilloid 4 Function in Mouse Esophageal Keratinocyte.
Dig Dis Sci. 60(12):3570-8357, 2015, Dec.
PMID:26233549
- Kurashina T, Dezaki K*, Yoshida M, Sukma Rita R, Ito K, Taguchi M, Miura
R, Tominaga M, Ishibashi S, Kakei M, Yada T*.
GHSR and downstream cAMP/TRPM2 signaling account for insulinostatic and glycemic effects of ghrelin.
Sci. Rep.5: 14041, 2015, Sep.
PMID:26370322
- Nishimoto R, Kashio M, Tominaga M*.
Propofol-induced pain sensation involves multiple mechanisms in sensory neurons
Pflugers Arch. 467: 2011-2020, 2015, Sep.
PMID:25301522
- Jang Y, Lee SH, Lee B, Jung S,Khalid A, Uchida K, Tominaga M, Jeon D*, Oh U*.
TRPM2, a Susceptibility Gene for Bipolar Disorder, Regulates Glycogen Synthase Kinase-3 Activity in the Brain
J Neurosci. 35(34):11811-11823, 2015, Aug.
PMID:26311765
- Peng G#, Kashio M#, Morimoto T, Li T, Zhu J, Tominaga M, Kadowaki T*.
Plant-Derived Tick Repellents Activate the Honey Bee Ectoparasitic Mite TRPA1.
Cell Reports. 12(2):190-202, 2015, July
表紙を飾りました!!
日本語要旨
# equal contribution
PMID:26146083
- Yoshiyama M*, Mochizuki T, Nakagomi H, Miyamoto T, Kira S, Mizumachi R,Sokabe T, Takayama Y, Tominaga M, Takeda M.
Functional roles of TRPV1 and TRPV4 in control of lower urinary tract activity: dual analysis of behavior and reflex during the micturition cycle.
Am J Physiol Renal Physiol. 308(10):F1128-1134. 2015, May
PMID:25761879
- Kashio M, Tominaga M*.
Redox signal-mediated enhancement of the temperature sensitivity of Transient Receptor Potential Melastatin 2 (TRPM2) elevated glucose-
induced insulin secretion from pancreatic islets.
J Biol Chem. 290(19):12435-12442, 2015, May
PMID:25817999
- Hatakeyama Y, Takahashi K, Tominaga M, Kimura H, Ohta T*.
Polysulfide evokes acute pain through the activation of nociceptive TRPA1 in mouse sensory neurons.
Mol Pain. 2;11(1):24. 2015, May
PMID:25934637
- Takayama Y, Uta D, Furue H, Tominaga M*.
Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons
PNAS. 112(16):5213-5218, 2015, Apr.
日本語要旨
PMID:25848051
- Saito S*, Tominaga M*.
Functional diversity and evolutionary dynamics of thermoTRPchannels
Cell Calcium 57(3):214-221, 2015, Mar.
PMID:25533790
Review,査読有
- Shibasaki K*, Tominaga M, Ishizaki Y.
Hippocampal neuronal maturation triggers post-synaptic clustering of brain temperature-sensor TRPV4.
Biochem Biophys Res Commun. 458(1):168-173, 2015, Feb.
PMID:25637662
- Ohara K*, Fukuda T, Okada H, Kitao S, Ishida Y, Kato K, Takahashi C, Katayama M, Uchida K, Tominaga M.
Identification of Significant Amino Acids in Multiple Transmembrane Domains of Human Transient Receptor Potential Ankyrin 1 (TRPA1) for Activation by Eudesmol, an Oxygenized Sesquiterpene in Hop Essential Oil.
J. Biol. Chem. 290(5):3161-3171, 2015, Jan.
PMID:25525269
- Aijima R, Wang B, Takao T,Mihara H, Kashio M, Ohsaki Y, Zhang J, Mizuno A, Suzuki M, Yamashita Y, Masuko S, Goto M, Tominaga M, Kido M*.
The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia.
FASEB J. 29(1):182-192, 2015, Jan.
日本語要旨
日本語要旨(Nature Japanjobs)
PMID:25351988
和文著書、和文総説
- 富永真琴, " TRPチャネルのレドックス制御" 別冊・医学のあゆみ 80-84(2015).
- 富永真琴, "TRPチャネル (TRPV1, TRPA1) と侵害刺激受容" Journal of Neuroscience for Pain Research 18, 1-5(2015).
- 富永真琴, "温度感受性TRPチャネルと疾患" ファルマシア 51 (11) 1047-1052(2015).
国際会議発表リスト
- M. Tominaga, "Lysophosphatidic acid-induced itch sensation involves LPA5 receptor-PLD signaling and TRPA/TRPV1" 10th International Conference for Neurons and Brain Disease, Xi’an (China), June 2015.
- S. Saito "Evolutionary change in thermoperception between Xenopus species inhabiting different thermal environments: from molecules to behavior"
SMBE2015 annual meeting of Society for Molecular Biology and Evolution,
Wien (Austria), June 2015.
- W. Sun, "Absence of TRPV2 impaired BAT thermogenesis in mice"
The 5th International Ion Channel Conference, Luzhou (China), June 2015.
- M. Tominaga, "Molecular mechanisms of nociception in the peripheral
nerve endings" 12th World Congress of Veterinary Anaesthesiology,
Kyoto (Japan), July 2015.
- M. Tominaga, "Regulation mechanisms of TRPV1 and TRPA1" 12th World Congress of Veterinary Anaesthesiology, Kyoto (Japan), July 2015.
- M. Tominaga, "TRP channels and pain" TRP2015 3rd Leuven TRP symposium, Leuven (Belgium), September 2015.
- Y. Takayama, "TRP1-ANO1 interaction in sensory neurons" TRP2015 3rd Leuven TRP symposium, Leuven (Belgium), September 2015.
- S. Derouiche, "Functional interaction between TRPV4 and ANO1 in salivary and lacrimal acinar cells" TRP2015 3rd Leuven TRP symposium, Leuven (Belgium), September 2015.
- R. Gupta, "Identification of single amino acid residue involved in the human TRPA1 inhibition by HC-030031 utilizing species specific differences" TRP2015 3rd Leuven TRP symposium, Leuven (Belgium), September 2015.
- H. Kittaka, "Cellular and molecular signaling of lysophosphatidic acid-induced itch sensation" 8th World Congress on Itch, Nara (Japan), September 2015.
- H. Kittaka, "LPA-induced peripheral itch sensation and cellular signaling involving LPA5 receptor, phospholipase D and TRPA1/TRPV1" Neuroscience2015, Chicago (USA), October 2015.
- W. Sun, "Absence of TRPV2 impaired BAT themogenesis in mice" The 8th Asia-Oceania Conference on Obesity, Nagoya (Japan), October 2015.
- M. Tominaga, "Analgesic mechanisms of essential oil components" The 13th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception, Fukuoka (Japan), November 2015.
- Y. Suzuki, "Role of TRPM6 and TRPM7 in maternal-fetal calcium transport" FAOPS2015, Bangkok (Thailand), November 2015.
- M. Tominaga, "Functional Interaction Between TRPV1/TRPA1 and Anoctamin 1" The 6th Asian Pain Symposium , Suzhou (China), November 2015.
招待講演
- 富永真琴「末梢神経での侵害刺激受容メカニズム」、第3回北河内産婦人科疼痛研究、大阪、2015年2月.
- 富永真琴「消化管機能とTRPチャネル」、第11回九州GIMDクラブ、福岡、2015年4月.
- 富永真琴「TRPチャネルによる侵害受容体機構」、第20回痛みの神経科学研究会、東京、2015年4月.
- 富永真琴「痛み、痒み感覚とTRPチャネル」、第2回GSK皮膚免疫カンファレンス、滋賀、2015年7月.
- 富永真琴「温度受容の分子機構」、第2回汗と皮膚疾患の研究会、東京、2015年8月.
- 富永真琴「温度感受性TRPチャネルと脳機能」、第59回脳の医学・生物学研究会、福岡、2015年8月.
- 富永真琴「TRPチャネルとかゆみ」、難治性かゆみの発症機構解明と予防・治療法開発の研究基盤構築 第2回公開シンポジウム、東京、2015年10月.
- 富永真琴「『温度受容チャネル研究の現在と未来』~熱や痛みのセンサー機構解明と創薬への期待」、豊田中央研究所、愛知、2015年11月.
バナースペース
生命創成探究センター
温度生物学研究G
(生理学研究所 細胞生理研究部門)