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2022

• *Kashio M, Masubuchi S, Tominaga M.
  Protein kinase C (PKC)-mediated phosphorylation of TRPM2 Thr738 counteracts the effect of cytosolic Ca²⁺ and elevates the temperature threshold.
  J Physiol. 2022 Aug 30. doi: 10.1113/JP283350. Epub ahead of print.
  PMID: 36042566.
  ＜プレスリリース＞
• *Saito S, Saito CT, Igawa T, Takeda N, Komaki S, Ohta T, Tominaga M.
  Evolutionary tuning of TRPA1 underlies the variation in heat avoidance behaviors among frog species inhabiting diverse thermal niches.
  Mol Biol Evol. 2022 Aug 22:msac180. doi: 10.1093/molbev/msac180. Epub ahead of print.
  PMID: 35994363.
  ＜プレスリリース＞
• Yoshimura A, *Saito S, Saito CT, Takahashi K, Tominaga M, *Ohta T.
  Functional analysis of thermo-sensitive TRPV1 in an aquatic vertebrate, masu salmon (Oncorhynchus masou ishikawae).
  Biochem Biophys Rep. 31:101315. 2022
  PMID: 35898728
  ＜プレスリリース＞
• Nguyen THD, Chapman S, Kashio M, Saito C, Strom T, Yasui M, *Tominaga M.
  Single amino acids set apparent temperature thresholds for heat-evoked activation of mosquito transient receptor potential channel TRPA1.
  J Biol Chem. 102271. 2022
  PMID: 35850302.
  ＜プレスリリース＞
• *Kashio M, *Tominaga M.
  TRP channels in thermosensation.
  Curr Opin Neurobiol. 75:102591. 2022
  PMID: 35728275
  review
• Sasajima S, Kondo M, Ohno N, Ujisawa T, Motegi M, Hayami T, Asano S, Asano-Hayami E, Nakai-Shimoda H, Inoue R, Yamada Y, Miura-Yura E, Morishita Y, Himeno T, Tsunekawa S, Kato Y, Nakamura J, Kamiya H, *Tominaga M.
  Thermal gradient ring reveals thermosensory changes in diabetic peripheral neuropathy in mice.
  Sci Rep. 12(1):9724. 2022
  PMID: 35697861
• Ujisawa T, Sasajima S, Kashio M, *Tominaga M.
  Thermal gradient ring reveals different temperature-dependent behaviors in mice lacking thermosensitive TRP channels.
  J Physiol Sci. 72(1):11. 2022
  PMID: 35624442
• *Boudaka A, Tominaga M.
  Physiological and Pathological Significance of Esophageal TRP Channels: Special Focus on TRPV4 in Esophageal Epithelial Cells.
  Int J Mol Sci. 23(9):4550. 2022
  PMID: 35562940
  review
• Sugisawa E, Kondo T, Kumagai Y, Kato H, Takayama Y, Isohashi K, Shimosegawa E, Takemura N, Hayashi Y, Sasaki T, Martino MM, Tominaga M, *Maruyama K.
  Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia.
  Cell Rep. 8;38(10):110462. 2022
  PMID: 35263589.
  ＜プレスリリース＞
• Derouiche S, Li T, Sakai Y, Uta D, Aoyagi S, *Tominaga M.
  Inhibition of TRPV1 and TRPA1 by mosquito and mouse saliva.
  Pain. 163(2):299-307, 2022
  PMID: 33990108
  ＜プレスリリース＞

2021

• Yokoyama T, Saito S, Shimoda M, Kobayashi M, Takasu Y, Sezutsu H, Kato Y, Tominaga M, Mizoguchi A, *Shiomi K.
  Comparisons in temperature and photoperiodic-dependent diapause induction between domestic and wild mulberry silkworms.
  Sci Rep. 11(1):8052.2021
  PMID: 33850226
  ＜プレスリリース＞
• Matsui T, Kadono-Maekubo N, Suzuki Y, Furuichi Y, Shiraga K, Sasaki H, Ishida A, Takahashi S, Okada T, Toyooka K, Sharif J, Abe T, Kiyonari H, Tominaga M, Miyawaki A, Amagai M.
  A unique mode of keratinocyte death requires intracellular acidification.
  PNAS. 118(17):e2020722118, 2021.
  PMID:33893234
  ＜プレスリリース＞
• Nishimoto R, Derouiche S, Eto K, Deveci A, Kashio M, Kimori Y, Matsuoka Y, Morimatsu H, Nabekura J, Tominaga M.
  Thermosensitive TRPV4 channels mediate temperature-dependent microglia movement.
  PNAS. 118(17):e2012894118, 2021.
  PMID:33888579
  ＜プレスリリース＞
• Kobayashi K, Ashina K, Derouiche S, Hamabata T, Nakamura T, Nagata N, Takenouchi S, Tominaga M, *Murata T.
  5,6-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid accelerates the healing of colitis by inhibiting transient receptor potential vanilloid 4-mediated signaling.
  FASEB J. 35(4):e21238, 2021.
  PMID:33715198
• Feng X, Song X, Tominaga M.
  Physiological significance of TRPV4 channels in non-myelinating Schwann cells.
  International Journal of Physical Medicine and Rehabilitation. (in press)
• Nguyen THD, Itoh SG, Okumura H, *Tominaga M.
  Structural basis for promiscuous action of monoterpenes on TRP channels.
  Commun Biol. 4(1):293, 2021
  PMID: 33674682
  ＜プレスリリース＞
• *Uchida K,Kita T, Hattaa K, Itoh SG, Okumura H, Tominaga M, Yamazakia J.
  Involvement of pore helix in voltage-dependent inactivation of TRPM5 channel.
  Heliyon. 7(1):e06102, 2021
  PMID:33553759

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