Yamaoka M, Maeda N*, Takayama Y, Sekimoto R, Tsushima Y, Matsuda K, Mori T, Inoue K, Nishizawa H, Tominaga M, Funahashi T, Shimomura I.
Adipose hypothermia in obesity and its association with period homolog 1, insulin sensitivity, and inflammation in fat. PLoS One. 14;9(11):e112813, 2014, Nov. PMID:25397888
Banzawa N, Saito S, Imagawa T, Kashio M, Takahashi K, Tominaga M, Ohta T*.
Molecular Basis Determining Inhibition/Activation of Nociceptive Receptor TRPA1: A Single Amino Acid Dictates Species-specific Actions of the Most Potent Mammalian TRPA1 Antagonists. J Biol Chem. 289(46):31927-31939, 2014, Nov PMID:25271161
Yoshida M, Dezaki K, Uchida K, Kodera S, Lam NV, Ito K, Rita RS, Yamada H, Shimomura K, Ishikawa SE, Sugawara H, Kawakami M, Tominaga M, Yada T, Kakei M*.
Involvement of cAMP-EPAC-TRPM2 activation in glucose- and incretin-induced insulin secretion. Diabetes 63(10):3394-3403, 2014, Oct. PMID:24824430
Okada Y*, Shirai K, Reinach PS, Kitano-Izutani A, Miyajima M, Flanders KC, Jester JV, Tominaga M, Saika S.
TRPA1 is required for TGF-β signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma. Lab Invest. 94(9):1030-1041, 2014, Sep. PMID:25068659
Tabuchi S, Tsunematsu T, Black SW, Tominaga M, Maruyama M, Takagi K, Minokoshi Y, Sakurai T, Kilduff TS, Yamanaka A.
Conditional Ablation of Orexin/Hypocretin Neurons: A New Mouse Model for the Study of Narcolepsy and Orexin System Function. J Nerosci. 34(19):6495-6509, 2014, May. PMID:24806676
Saito S*, Banzawa N, Fukuta N, Saito CT, Takahashi K, Imagawa T, Ohta T, Tominaga M*.
Heat and noxious chemical sensor, chicken TRPA1, as a target of bird repellents and identification of its structural determinants by multispecies functional comparison. Mol Biol Evol 31(3):708-722, 2014, Mar. 日本語要旨 PMID: 24398321
Hirai T, Enomoto M*, Kaburagi H, Sotome S, Yoshida-Tanaka K, Ukegawa M,
Kuwahara H, Yamamoto M, Tajiri M, Miyata H, Hirai Y, Tominaga M, Shinomiya K, Mizusawa H, Okawa A, Yokota T*.
Intrathecal AAV serotype 9-mediated delivery of shRNA against TRPV1 attenuates thermal hyperalgesia in a mouse model of peripheral nerve injury. Mol. Ther. 22(2):409-419, 2014, Feb. PMID:24322332
S.Saito, "Molecular basis for the specific differences in heat receptor
TRPV1 related to thermal adaptation in Xenopus species" SMBE2014 annual meeting of Society for Molecular Biology
and Evolution, San Juan(Puerto Rico) June 2014.
M. Tominaga, "A pain-enhancing mechanism through interaction between TRP channels and anoctamines" 9th International Conference for Neurons and Brain Disease, Madrid (Spain), July 2014.
H. Kittaka, " Involvement of lysophosphatidic acid-evoked activation of TRPA1 and TRPV1 in peripheral itch sensation in mice" 24th International Symposium of Itch, Tokyo (Japan), August 2014.
M. Tominaga, "Functional Regulation of TRPM5 and TRPA1" The 11th International Symposium on Molecular and Neural Mechanisms of taste and Olfactory Perception, Fukuoka (Japan), October 2014.
M. Tominaga, "Functional Interaction between TRP channels and Anoctamin1" The 12th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception, Fukuoka (Japan), November 2014.
Y. Takayama, "A pain-enhancing mechanism through TRPA1-ANO1 interaction, and its inhibition effect by drag" Neuroscience2014, Washington D.C. (USA), November 2014.
M. Tominaga, "Molecular mechanisms for detecting noxious stimuli in the peripheral nerve endings" New Directions in Pain Neuroscience, Osaka (Japan), December 2014.
Thermal Biology Group, Exploratory Research Center on Life and Living Systems(ExCELLS),
Division of Cell Signaling, National Institute for Physiological Sciences,
(previous;Division of Cell Signaling, Okazaki Institute for Integrative