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業績Publication


2020

  • *Matsumoto K, Deguchi A, Motoyoshi A, Morita A, Maebashi U, Nakamoto T, Kawanishi S, Sueyoshi M, Nishimura K, Takata K, Tominaga M, Nakahara T, Kato S.
    Role of transient receptor potential vanilloid subtype 4 in the regulation of azoymethane/dextran sulphate sodium-induced colitis-associated cancer in mice.
    Eur J Pharmacol. 867:172853. 2020
    PMID: 31836532
  • *Mihara H, Boudaka A, Tominaga M, Sugiyama T.
    Transient Receptor Potential Vanilloid 4 Regulation of Adenosine Triphosphate Release by the Adenosine Triphosphate Transporter Vesicular Nucleotide Transporter, a Novel Therapeutic Target for Gastrointestinal Baroreception and Chronic Inflammation.
    Digestion. 2020;101(1):6-11.
    PMID:31770754
    review

2019

  • Li T, Saito CT, Hikitsuchi T, Inoguchi Y, Mitsuishi H, *Saito S, *Tominaga M.
    Diverse sensitivities of TRPA1 from different mosquito species to thermal and chemical stimuli.
    Sci Rep. 9(1):20200.2019
    PMID:31882848
  • Fricke TC, Echtermeyer F, Zielke J, de la Roche J, Filipovic MR, Claverol S, Herzog C, Tominaga M, Pumroy RA, Moiseenkova-Bell VY, Zygmunt PM, *Leffler A, Eberhardt MJ.
    Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2.
    Proc Natl Acad Sci U S A. 116(48):24359-24365.2019
    PMID:31719194
  • *Shibasaki K, Yamada K, Miwa H, Yanagawa Y, Suzuki M, Tominaga M, Ishizaki Y.
    Temperature elevation in epileptogenic foci exacerbates epileptic discharge through TRPV4 activation
    Lab Invest. (2019) doi:10.1038/s41374-019-0335-5
    PMID:31641226
  • *Saito S, Saito CT, Nozawa M, Tominaga M.
    Elucidating the functional evolution of heat sensors among Xenopus species adapted to different thermal niches by ancestral sequence reconstruction.
    Mol Ecol. 28(15):3561-3571.2019
    PMID:31291493
    プレスリリース
  • *Uchida K, Fukuta N, Yamazaki J, *Tominaga M.
    Identification and classification of a new TRPM3 variant (γ subtype).
    J Physiol Sci. 69(4):623-634. 2019
    PMID:31011981
  • *Takayama Y, *Derouiche S, *Maruyama K, *Tominaga M.
    Emerging Perspectives on Pain Management by Modulation of TRP Channels and ANO1.
    Int J Mol Sci. 20(14). 2019
    PMID:31336748
    review
  • Araki K, Araki A, Honda D, Izumoto T, Hashizume A, Hijikata Y, Yamada S, Iguchi Y, Hara A,Ikumi K, Kawai K, Ishigaki S, Nakamichi Y, Tsunekawa S, Seino Y, Yamamoto A, Takayama Y, Hidaka S, Tominaga M, Ohara-Imaizumi M, Suzuki A, Ishiguro H, Enomoto A, Yoshida M, Arima H, Muramatsu S, Sobue G, *Katsuno M.
    TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets.
    J Clin Invest. 2019;129(9):3578–3593.
  • *Hirata Y, Suzuki Y, Tominaga M, *Oku Y.
    TRPM8 channel is involved in the ventilatory response to CO2 mediating hypercapnic Ca2+ responses.
    Respir Physiol Neurobiol. 263:20-25. 2019.
    PMID:30844520
  • *Matsumoto K, Ohishi A, Iwatsuki K, Yamazaki K, Takayanagi S, Tsuji M, Aihara E, Utsumi D, Tsukahara T, Tominaga M, Nagasawa K, Kato S.
    Transient receptor potential vanilloid 4 mediates sour taste sensing via type III taste cell differentiation.
    Sci Rep. 30;9(1):6686. 2019.
    PMID:31040368
  • Ota W, Nakane Y, Kashio M, Suzuki Y, Nakamura K, Mori Y, Tominaga M, *Yoshimura T.
    Involvement of TRPM2 and TRPM8 in temperature-dependent masking behavior.
    Sci Rep.9(1):3706. 2019
    PMID:30742533
  • Kita T, *Uchida K, Kato K, Suzuki Y, Tominaga M, Yamazaki J.
    FK506 (tacrolimus) causes pain sensation through the activation of transient receptor potential ankyrin 1 (TRPA1) channels.
    J Physiol Sci. 69(2):305-316. 2019
    PMID:30478741
  • Shimada T, Takahashi K, Tominaga M, *Ohta T.
    Identification of molecular targets for toxic action by persulfate, an industrial sulfur compound.
    Neurotoxicology. 72:29-37. 2019
    PMID:30738091
  • Okada Y, Sumioka T, Ichikawa K, Sano H, Nambu A, Kobayashi K, Uchida K, Suzuki Y, Tominaga M, Reinach PS, Hirai SI, Jester JV, Miyajima M, Shirai K, Iwanishi H, Kao WW, Liu CY, *Saika S.
    Sensory nerve supports epithelial stem cell function in healing of corneal epithelium in mice: the role of trigeminal nerve transient receptor potential vanilloid 4.
    Lab Invest. 99(2):210-230.2019
    PMID:30413814

英文著書

和文著書、和文総説

  • 富永真琴:痛みと侵害受容器 ペインクリニック 2019; 401 (1): 9-16.
  • 齋藤 茂、富永真琴
    「温度センサーTRPチャネルの生息環境に応じた機能進化とその構造基盤」
    生物物理 59(1):5-8 (2019)
    表紙を飾りました!!
  • 富永真琴:温度を感じるメカニズム―TRPチャネルの関与 脳神経外科 2019; 90 (6): 603-608.
  • 富永真琴、曽我部隆彰:TRPチャネルによる昆虫の温度センシング 昆虫と自然 2019; 54 (11): 30-33.
  • 富永真琴:TRPチャネルと温度受容 Clinical Neuroscience 2019; 37 (12): 1521-1523.

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生命創成探究センター
 温度生物学研究G
(生理学研究所 細胞生理研究部門)