研究成果/学術論文(英文)
2020
- Kataoka N, Shima Y, Nakajima K, *Nakamura K.
A central master driver of psychosocial stress responses in the rat.
Science 367:1105–1112, 2020.
PMID:32139538
<プレスリリース>
<English ver.>
Natuerに研究紹介が掲載されました。<https://www.nature.com/articles/d41586-020-00873-0>
- Shiomi A, Nagao K, Kasai H, Hara Y, *Umeda M.
Changes in the physicochemical properties of fish cell membranes during cellular senescence.
Biosci Biotechnol Biochem. 84(3):583-593. 2020
PMID:31760866
- Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, *Nishitoh H.
ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.
Life Sci Alliance. inpress.
PMID:32029570
<領域内連携>
- Shibasaki K.
TRPV4 activation by thermal and mechanical stimuli in disease progression.
Lab Invest. 100(2):218-223. 2020
PMID:31896814
Review Article
- *Shibasaki K, Yamada K, Miwa H, Yanagawa Y, Suzuki M, Tominaga M, Ishizaki Y.
Temperature elevation in epileptogenic foci exacerbates epileptic discharge through TRPV4 activation.
Lab Invest. 100(2):274-284. 2020
PMID:31641226
<プレスリリース>
- Oda M, Yamamoto H, Matsumoto H, Ishizaki Y, *Shibasaki K.
TRPC5 regulates axonal outgrowth in developing retinal ganglion cells.
Lab Invest. 100(2):297-310.2020
PMID:31844148
- *Inomata N, Inaoka R, Okabe K, Funatsu T, Ono T.
Short-term temperature change detections and frequency signals in single cultured cells using a microfabricated thermistor
Sens Biosensing Res.27 in press (https://doi.org/10.1016/j.sbsr.2019.100309)
<領域内連携>
- Nakano S, Ikeda M, Tsukada Y, Fei X, Suzuki T, Niino Y, Ahluwalia R, Sano A, Kondo R, Ihara K, Miyawaki A, Hashimoto K, Higashiyama T, *Mori I.
Presynaptic MAST kinase controls opposing postsynaptic responses to convey stimulus valence in Caenorhabditis elegans.
Proc Natl Acad Sci U S A. 117(3):1638-1647. 2020
PMID:31911469
- Yamamo S, Kimura M, Chen Y, *Imamoto N, *Ohki R.
Nuclear import of IER5 is mediated by a classical bipartite nuclear localization signal and is required for HSF1 full activation.
Exp. Cell Res. 386, 2020
PMID: 31669744
2019
- Ogihara T, *Nakagawa T, Hayashi M, Koyanagi M, Yonezawa A, Omura T, Nakagawa S, Kitada N, Imai S, Matsubara K.
Improvement of peripheral vascular impairment by a phosphodiesterase type 5 inhibitor tadalafil prevents oxaliplatin-induced peripheral neuropathy in mice.
J Pharmacol Sci. 141(4):131-138. 2019
PMID:31734027
- Ueda M, Matsui A, Watanabe S, Kobayashi M, Saito K, Tanaka M, Ishida J, Kusano M, Seo M, *Seki M.
Transcriptome analysis of the hierarchical response of HDAC proteins that respond in an antagonistic manner to salinity stress.
Front. Plant Sci. 10: 1323, 2019
PMID:31681394
- Sha E, Nakamura M, Ankai K, Yamamoto YY, Oka T, *Yohda M.
Functional and structural characterization of HspB1/Hsp27 from Chinese hamster ovary cells
FEBS Open Bio. ;9(10):1826-1834. 2019
PMID:31441240
- Fukutani Y, Tamaki R, Inoue R, Koshizawa T, Sakashita S, Ikegami K, Ohsawa I, Matsunami H, *Yohda M.
The N-terminal region of RTP1S plays important roles in dimer formation and odorant receptor-trafficking.
J Biol Chem. 294(40):14661-14673. 2019
PMID:31395660
- Otsuka C, Wakahara Y, Okabe K, Sakata J, Okuyama M, Hayashi A,Tokuyama H, *Uchiyama, S.
Fluorescent Labeling Method Re-Evaluates the Intriguing Thermoresponsive Behavior of Poly(acrylamide-co-acrylonitrile)s with Upper Critical Solution Temperatures.
MACROMOLECULES 52(20): 7646-7660,2019
- Kamiya A, Hayama Y, Kato S, Shimomura A, Shimomura T, Irie K, Kaneko R, Yanagawa Y, Kobayashi K, Ochiya T.
Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression.
Nat Neurosci. 22(8):1289-1305.2019
PMID:31285612
- *Saito S, Saito CT, Nozawa M, Tominaga M.
Elucidating the functional evolution of heat sensors among Xenopus species adapted to different thermal niches by ancestral sequence reconstruction.
Mol Ecol. 28(15):3561-3571.2019
PMID:31291493
<プレスリリース>
- Chernyshova K, Inoue K, Yamashita SI, *Fukuchi T, *Kanki T.
Glaucoma-Associated Mutations in the Optineurin Gene Have Limited Impact on Parkin-Dependent Mitophagy.
Invest Ophthalmol Vis Sci. 60(10):3625-3635. 2019
PMID:31469402
- Kimura M, Sasaki K, Fukutani Y, Yoshida H, Ohsawa I, Yohda M, *Sakurai K.
Anticancer saponin OSW-1 is a novel class of selective Golgi stress inducer.
Bioorg Med Chem Lett. 29(14):1732-1736. 2019
PMID:31126855
- Matsuo N, *Nagao K, Suito T, Juni N, Kato U, Hara Y, *Umeda M.
Different mechanisms for selective transport of fatty acids using a single class of lipoprotein in Drosophila.
J Lipid Res. 60(7):1199-1211.2019
PMID:31085629
- *Nakayama K, Inaba Y.
Genetic variants influencing obesity-related traits in Japanese population.
Ann Hum Biol. 46(4):298-304. 2019
PMID:31307227
- *#Doi M, #Shimatani H, #Atobe Y, Murai I, Hayashi H, Takahashi Y, Fustin JM, Yamaguchi Y, Kiyonari H, Koike N, Yagita K, Lee C, Abe M, Sakimura K, *Okamura H.
Non-coding cis-element of Period2 is essential for maintaining organismal circadian behaviour and body temperature rhythmicity.
Nat Commun. 10(1):2563. 2019.
PMID:31189882
<詳しくはこちら>
<プレスリリース>
#同等貢献著者, *責任著者
- Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, *Asano T.
Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.
Cell Rep. 26(12):3221-3230.e3. 2019
PMID:30893596
<詳しくはこちら>
<プレスリリース>
<領域内連携>
- Sharma N, Baek K, Shimokawa N, and *Takagi M.
Effect of temperature on raft-dependent endocytic cluster formation during activation of Jurkat T cells by concanavalin A
J. Biosci. Bioeng., 127(4):479-485.2019
PMID:30355461
- Okahata M, Wei A. D, *Ohta A, *Kuhara A.
Cold acclimation via the KQT-2 potassium channel is modulated by oxygen in Caenorhabditis elegans
Science Advances, 5, eaav3631, 2019
<詳しくはこちら>
- *Morrison SF, Nakamura K.
Central mechanisms for thermoregulation.
Annu. Rev. Physiol. 81: in press, 2019.
PMID:30256726
review
- Shimauchi-Ohtaki H, Kurachi M, Naruse M, Shibasaki K, Sugio S, Matsumoto K, Ema M, Yoshimoto Y, *Ishizaki Y.
The dynamics of revascularization after white matter infarction monitored in Flt1-tdsRed and Flk1-GFP mice.
Neurosci. Lett.692:70-76.2019
PMID:30389418
- Yoh T, Hatano E, Kasai Y, Fuji H, Nishi K, Toriguchi K, Sueoka H, Ohno M, Seo S, Iwaisako K, Taura K, Yamaguchi R, Kurokawa M, Fujimoto J, Kimura T, Uemoto S, *Nishi E.
Serum nardilysin, a surrogate marker for epithelial-mesenchymal transition, predicts prognosis of intrahepatic cholangiocarcinoma after surgical resection
Clin Cancer Res. 25(2):619-628.2019
PMID:30352908
2018
- *Nakamura K.
Chapter 16 - Afferent pathways for autonomic and shivering thermoeffectors.
In: Handbook of Clinical Neurology (Thermoregulation: From Basic Neuroscience to Clinical Neurology Part I), ed. by Romanovsky, A.A.: Elsevier, Vol. 156, Pages 263–279, 2018.
book chapter
- Minami S, Nomura H, *Minami M.
Exposure to hot and cold environments increases noradrenaline release in the bed nucleus of the stria terminalis in rats.
Neuropsychopharmacol. Rep. 38(4):214-218, 2018
PMID: 30341818
- Yamauchi N, Takahashi D, Sugimura YK, Kato F, Amano T, *Minami M.
Activation of the neural pathway from the dorsolateral bed nucleus of the stria terminalis to the central amygdala induces anxiety-like behaviors.
Eur. J. Neurosci. 48(9):3052-3061, 2018.
PMID: 30240530
- Isami K, *Imai S, Sukeishi A, Nagayasu K, Shirakawa H, *Nakagawa T, Kaneko S.
The impact of mouse strain-specific spatial and temporal immune responses on the progression of neuropathic pain.
Brain Behav Immun. 74:121-132.2018
PMID:30171890
- *Koba S, Hanai E, Kumada N, Kataoka N, Nakamura K, Watanabe T.
Sympathoexcitation by hypothalamic paraventricular nucleus neurons projecting to the rostral ventrolateral medulla.
J. Physiol. 596:4581–4595, 2018.
PMID:30019338
- Sekiguchi T, Sotoma S, Harada Y.
Fluorescent Nanodiamonds as a Robust Temperature Sensor inside a Single Cell.
Biophys Physicobiol. 15:229-234. 2018
PMID:30450272
- *Furukawa K, *Kanki T.
PP2A-like protein phosphatase Ppg1: an emerging negative regulator of mitophagy in yeast.
Autophagy. 14(12):2171-2172.2018
PMID: 30145928
Commentary
- *Nakamura K, Nakamura Y.
Hunger and satiety signaling: Modeling two hypothalamomedullary pathways for energy homeostasis.
BioEssays 40(8):1700252, 2018
PMID:29869415
review
- *Nakaminami K, Seki M.
RNA regulation in plant cold stress response.
In: “Survival Strategies in Extreme Cold and Desiccation: Adaptation Mechanisms and their Applications. Advances in Experimental Medicine and Biology (Edited by Iwaya-Inoue M, Sakurai M, Uemura M)”Springer Japan,
Adv Exp Med Biol. 1081:23-44, 2018.
PMID: 30288702
review
- Aoki I, Tateyama M, Shimomura T, Ihara K, Kubo Y, Nakano S, *Mori I.
SLO potassium channels antagonize premature decision making in C. elegans.
Communications Biology 1: 123, 2018
PMID: 30272003
<プレスリリース>
- Matsumoto H, Sugio S, Seghers F, Krizaj D, Akiyama H, Ishizaki Y, Gailly P, *Shibasaki K.
Retinal detachment-induced Müller glial cell swelling activates TRPV4 ion channels and triggers photoreceptor death at body temperature.
J Neurosci.38(41): 8745-8758, 2018
PMID:30143574
<詳しくはこちら>
<プレスリリース>
- Hiyama H, Yano Y, So K, Imai S, Nagayasu K, Shirakawa H, *Nakagawa T, Kaneko S.
TRPA1 sensitization during diabetic vascular impairment contributes to cold hypersensitivity in a mouse model of painful diabetic peripheral neuropathy.
Mol Pain 14: 1-14, 2018.
PMID:29968518
- Ujisawa T, *Ohta A, Ii T, Minakuchi Y, Toyoda A, Ii M, *Kuhara A.
Endoribonuclease ENDU-2 regulates multiple traits including cold tolerance via cell autonomous and nonautonomous controls in Caenorhabditis elegans.
PNAS 115(35):8823-8828,2018
PMID:30104389
<詳しくはこちら>
<プレスリリース>
- Suito T, Nagao K, Hatano M, Kohashi K, Tanabe A, Ozaki H, Kawamoto J, Kurihara T, Mioka T, Tanaka K, Hara Y, *Umeda M.
Synthesis of omega-3 long-chain polyunsaturated fatty acid-rich triacylglycerols in an endemic goby, Gymnogobius isaza, from Lake Biwa, Japan.
J Biochem. 164(2):127-140. 2018
PMID:29554278
- Ohnishi K, Takagaki N, Okahata M, Fujita M, Ohta A, *Kuhara A.
Molecular and Cellular Network Systems Underlying Cold Tolerance of Caenorhabditis elegans
Cryobiology and Cryotechnology, in press
Review
- *Kuhara A, Ohta A.
Temperature response in cold tolerance of C. elegans
Impact, 2018, 7, 44-46, 2018
Review, 査読なし
- *Kinbara K, Umetsu K. Sonobe H. Muraoka T. Shimokawa N. Takagi M.
Localization of transmembrane multiblock amphiphilic molecules in phase-separated vesicles.
Faraday Discuss. inpress 2018
PMID:30015339
- *Ogawa Y, *Imamoto N.
Nuclear transport adapts to varying heat stress in a multistep mechanism.
J Cell Biol. 217(7):2341-2352. 2018
PMID:29748335
- Yamashita SI, *Kanki T.
Detection of Iron Depletion- and Hypoxia-Induced Mitophagy in Mammalian Cells.
Methods Mol Biol. 1782:315-324.2018
PMID: 29851008
Review
- Nakaminami K, Okamoto M, Higuchi-Takeuchi M, Yoshizumi T, Yamaguchi Y, Fukao Y, Shimizu M, Ohashi C, Tanaka M, Matsui M, Shinozaki K, *Seki M. *Hanada K.
AtPep3 is a hormone-like peptide that plays a role in salinity stress tolerance of plants.
Proc. Natl. Acad. Sci. USA 115:5810-5815, 2018
PMID: 29760074
- *Liu J, *Sokabe T, Montell C.
A Temperature Gradient Assay to Determine Thermal Preferences of Drosophila Larvae.
J. Vis. Exp. (136), e57963 (2018).
*Equally contributed.
- *Saito H , Morishita T, Mizukami T, Nishiyama K, Kawaguchi K, Nagao H.
Molecular dynamics study of binary POPC bilayers: molecular condensing effects on membrane structure and dynamics.
J. Physics in press.
- Hoshi T, Okabe K, Shibasaki K, Funatsu T, Matsuki N, Ikegaya Y, *Koyama R.
Ischemic brain injury leads to brain edema via hyperthermia-induced TRPV4 activation.
J Neurosci. 38(25):5700-5709, 2018
PMID:29793978
<領域内連携>
- *Furukawa K, Fukuda T, Yamashita SI, Saigusa T, Kurihara Y, Yoshida Y, Kirisako H, Nakatogawa H, *Kanki T.
The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated Phosphorylation of Atg32 to Inhibit Mitophagy.
Cell Rep. 23(12):3579-3590. 2018
PMID:29925000
<プレスリリース>
- Suzuki Y, *Chitayat D, Sawada H, Deardorff MA, McLaughlin HM, Begtrup A, Millar K, Harrington J, Chong K, Roifman M, Grand K, Tominaga M, Takada F, Shuster S, Obara M, Mutoh H, Kushima R, Gen Nishimura G.
TRPV6 Variants Interfere with Maternal-Fetal Calcium Transport through the Placenta and Cause Transient Neonatal Hyperparathyroidism
Am J Hum Genet. 102(6):1104-1114. 2018
PMID:29861107
<プレスリリース>
- *Imamoto N.
Heat stress-induced nuclear transport mediated by Hikeshi confers nuclear function of Hsp70s.
Curr Opin Cell Biol. 52:82-87. 2018
PMID:29490261
Review,
- *Nakamura K, Nakamura Y.
Hunger and satiety signaling: Modeling two hypothalamomedullary pathways
for energy homeostasis.
Bioessays. e1700252. 2018
PMID:29869415
Review
- Ishii T, Uchida K, Hata S, Hatta M, Kita T, Miyake Y, Okamura K, Tamaoki S, Ishikawa H, *Yamazaki J.
TRPV2 channel inhibitors attenuate fibroblast differentiation and contraction mediated by keratinocyte-derived TGF-β1 in an in vitro wound healing model of rats
J. Dermatological Sci. 90(3);332-342, 2018
PMID:29610016
- Ohashi K, Deyashiki K, Miyake T, Nagayasu K, Shibasaki K, *Shirakawa H, Kaneko S.
TRPV4 is functionally expressed in oligodendrocyte precursor cells and increases their proliferation.
Pflugers Arch. 470(5):705-716. 2018
PMID:29569183
- *Miyake M, Kakizawa Y, Tobori N, Kurioka M, Tabuchi N, Kon R, Shimokawa N, Tsujino Y, Takagi M.
Membrane permeation of giant unilamellar vesicles and corneal epithelial cells with lipophilic vitamin nanoemulsions.
Colloids Surf B Biointerfaces. 169:444-452. 2018
PMID:29852433
- Tsuchiya M, *Hara Y, Okuda M, Itoh K, Nishioka R, Shiomi A, Nagao K, Mori M, Mori Y, Ikenouchi J, Suzuki R, Tanaka M, Ohwada T, Aoki J, Kanagawa M, Toda T, Nagata Y, Matsuda R, Takayama Y, Tominaga M, *Umeda M.
Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation.
Nat Commun. 9(1):2049. 2018
PMID:29799007
<プレスリリース>
<領域内連携>
- Ichikawa S, Shimokawa N, Takagi M, Kitayama Y, *Takeuchi T .
Size-dependent uptake of electrically neutral amphipathic polymeric nanoparticles by cell-sized liposomes and an insight into their internalization mechanism in living cells.
Chem Commun (Camb). 54(36):4557-4560. 2018
PMID:29662978
- Phan H, Shimokawa N, Sharma N, Takagi M, *Vestergaad M.
Strikingly different effects of cholesterol and 7-ketocholesterol on lipid bilayer-mediated aggregation of amyloid beta (1-42).
Biochem Biophys Rep. 14:98-103. 2018
PMID:29872741
- #Abe Y, #Fujiwara Y, #Takahashi H, Matsumura Y, Sawada T, Jiang S, Nakaki R, Uchida A, Nagao N, Naito M, Kajimura S, Kimura H, Osborne TF, Aburatani H, Kodama T, *Inagaki T, *Sakai J.
Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch
Nat Commun. 9(1):1566, 2018
PMID:29674659
<プレスリリース 東大>
<プレスリリース 東北大>
- *Derouiche S, Takayama Y, Murakami M, *Tominaga M.
TRPV4 heats up ANO1-dependent exocrine gland fluid secretion.
FASEB J. 32(4):1841-1854, 2018
PMID:29187363
<プレスリリース>
- *Karasawa T, Kawashima A, Usui-Kawanishi F, Watanabe S, Kimura H, Kamata R, Shirasuna K, Koyama Y, Sato-Tomita A, Matsuzaka T, Tomoda H, Park SY, Shibayama N, Shimano H, Kasahara T, *Takahashi M.
Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.
Arterioscler Thromb Vasc Biol. 38(4):744-756, 2018
PMID:29437575
- Nakamura S, Suzuki S, Saito H, *Nishiyama KI.
Cholesterol blocks spontaneous insertion of membrane proteins into liposomes of phosphatidylcholine.
J Biochem. 163(4):313-319, 2018
PMID:29228210
- Nakamura Y, *Nakamura K.
Central regulation of brown adipose tissue thermogenesis and energy homeostasis dependent on food availability.
Pflügers Arch. - Eur. J. Physiol. 470(5):823-837, 2018
PMID: 29209779
Review
- *Okabe K, Sakaguchi R, Shi B, *Kiyonaka S.
Intracellular thermometry with fluorescent sensors for thermal biology.
Pflugers Arch. 470(5):717-731, 2018
PMID:29397424
- *Nomura T, Yamashita W, Gotoh H, Ono K.
Species-specific mechanisms of neuron subtype specification reveal evolutionary plasticity of amniote brain development.
Cell Reports 22(12): 3142-3151, 2018
PMID:29562171
<詳しくはこちら>
<プレスリリース>
- *Fukuda T, *Kanki T.
Mechanisms and Physiological Roles of Mitophagy in Yeast.
Mol Cells. 41(1):35-44, 2018
PMID: 29370687
- #Goda T, #Doi M, Umezaki Y, Murai I, Shimatani H, Chu ML, Nguyen VH, *Okamura H, *Hamada FN.
Calcitonin receptors are ancient modulators for rhythms of preferential temperature in insects and body temperature in mammals.
Genes & Development, 32(2):140-155, 2018
PMID:29440246
#同等貢献著者, *責任著者
<詳しくはこちら>
<プレスリリース>
- *Nomura T, Gotoh H, Ono K.
The Future Vocation of Neural Stem Cells: Lineage Commitment in Brain Development and Evolution.
Neurochem Res. 43(1):153-156, 2018
PMID:28836066
- Eto K, Kim SK, Takeda I, *Nabekura J.
The roles of cortical astrocytes in chronic pain and other brain pathologies.
Neurosci Res. 126:3-8, 2018
PMID:28870605
- #Tainaka M, #*Doi M, Inoue Y, Murai I, *Okamura H.
Circadian PER2 protein oscillations do not persist in cycloheximide-treated mouse embryonic fibroblasts in culture.
Chronobiol. Int. 35(1):132-136,2018
PMID:29283306
- Fujita T, Liu Y, Higashitsuji H, Itoh K, Shibasaki K, *Fujita J, Nishiyama H.
Involvement of TRPV3 and TRPM8 ion channel proteins in induction of mammalian cold-inducible proteins.
Biochem Biophys Res Commun. 495(1):935-940,2018
PMID:29175331
<領域内連携>
- *Inomata N, Toda M, Ono T.
Microfabricated Temperature-Sensing Devices Using a Microfluidic Chip for Biological Applications
Int. J. of Automation Technology, 12(1), 15-23, 2018
Review
- *Imamoto N.
Regulating β-catenin nuclear import with the small GTPase Rap.
Developmental Cell 44, 135-136, 2018.
PMID:29401416
プレビュー
2017
- Suito T, *Nagao K, *Umeda M.
Transport and Metabolism of Carotenoids in Drosophila melanogaster.
Carotenoid Science. 22, 1-5, 2017
- *Inomata N, Toan NV, Ono T.
Piezoresistive property of an aluminum-doped zinc oxide thin film deposited via atomic-layer deposition for microelectromechanical system/nanoelectromenchanical system applications
IEEJ Trans., 12(S2), S120-S124, 2017.
- Murakami A, *Nagao K, Juni N, Hara Y, *Umeda M.
An N-terminal di-proline motif is essential for fatty acid-dependent degradation of Δ9-desaturase in Drosophila.
J Biol Chem. 292(49):19976-19986, 2017
PMID:28972163
- Mimura Y, Takemoto S, Tachibana T, Ogawa Y, Nishimura M, *Yokota H, *Imamoto N.
A statistical image analysis framework for pore-free islands derived from heterogeneity distribution of nuclear pore complexes.
Sci Rep. 7(1):16315, 2017
PMID: 29176624
<プレスリリース>
- Oyama S, Dogishi K, Kodera M, Kakae M, Nagayasu K, Shirakawa H, *Nakagawa T, Kaneko S.
Pathophysiological Role of Transient Receptor Potential Ankyrin 1 in a Mouse Long-Lasting Cystitis Model Induced by an Intravesical Injection of Hydrogen Peroxide.
Front Physiol. 8:877, 2017
PMID:29249972
- Rahman K.M.Z., Kose S, *Imamoto N.
Effect of an inhibitor of HSP70, YM-1 on Hikeshi knockout cells.
Thermal Medicine 33, 129-134, 2017
- Sukeishi A, Isami K, Hiyama H, Imai S, Nagayasu K, Shirakawa H, *Nakagawa T, Kaneko S.
Colchicine alleviates acute postoperative pain but delays wound repair in mice: roles of neutrophils and macrophages.
Mol. Pain 13: 1-12, 2017
PMID: 29108466
- Rahman KMZ, Mamada H, Takagi M, Kose S, *Imamoto N.
Hikeshi modulates the proteotoxic stress response in human cells: Implication for the importance of the nuclear function of HSP70s.
Genes Cells. 22(11):968-976, 2017
PMID:28980748
- Miyake T, Nakamura S, Meng Z, Hamano S, Inoue K, Numata T, Takahashi N, Nagayasu K, Shirakawa H, Mori Y, Nakagawa T, Kaneko S.
Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin.
Front Physiol. 8:878, 2017
PMID:29163216
- Jo A, Noel J, Lakk M, Yarishkin O, Ryskamp D, Shibasaki K, Maureen A McCall, *Krizaj D.
Mouse retinal ganglion cell signaling is dynamically modulated through parallel anterograde activation of cannabinoid and vanilloid pathways.
J. Physiol.595(20):6499-6516, 2017
PMID:28766743
<国際共同研究加速基金による共同研究>
- *Uchida K, Dezaki K, Yoneshiro T, Watanabe T, Yamazaki J, Saito M, Yada T, Tominaga M, *Iwasaki Y.
Involvement of thermosensitive TRP channels in energy metabolism.
J Physiol Sci. 67(5):549-560, 2017
PMID:28656459
Review.
- Yamashita W, Shimizu T, *Nomura T.
In Vitro and Ex Ovo Culture of Reptilian and Avian Neural Progenitor Cells.
Methods Mol Biol.1650:259-265, 2017
PMID:28809027
Part of the Methods in Molecular Biology book series (MIMB, volume 1650)
- Yahiro T, Kataoka N, Nakamura Y, *Nakamura K.
The lateral parabrachial nucleus, but not the thalamus, mediates thermosensory pathways for behavioural thermoregulation.
Sci. Rep. 7:5031, 2017
PMID:28694517
<プレスリリース>(名古屋大学 日本語版))
<プレスリリース>(名古屋大学 英語版)
<プレスリリース>(科学技術振興機構)
<詳しくはこちら>
- Yamashita SI, *Kanki T.
Detection of Hypoxia-Induced and Iron Depletion-Induced Mitophagy in Mammalian Cells.
Methods Mol. Biol. in press.
PMID:28324492
- Furukawa K, *Kanki T.
Mitophagy in Yeast: A Screen of Mitophagy-Deficient Mutants.
Methods Mol. Biol. in press.
PMID:28324487
- *Inomata N, Ono T.
Geometry dependence of temperature coefficient of resonant frequency in highly sensitive resonant thermal sensors.
Japanese Journal of Applied Physics 56, 087201, 2017
- *Nakagawa T, Kaneko S.
Roles of transient receptor potential ankyrin 1 in oxaliplatin-induced peripheral neuropathy.
Biol. Pharm. Bull. 40(7):947-953, 2017.
PMID:28674258
Review
Biol. Pharm. Bull.の表紙を飾りました!!
- Sugahara K, *Shimokawa N, Takagi M.
Thermal Stability of Phase-Separated Domains in Multicomponent Lipid Membranes with Local Anesthetics.
Membranes (Basel). 7(3),33, 2017
PMID:28661445
- Deftu AF, Filippi A, Shibsaki K, Gheorghe RO, Chiritoiu M, Ristoiu V.
CXCL1 and CXCL2 chemokines modulate the activity of TRPV1+/IB4+ cultured rat dorsal ganglia neurons upon short-term and acute application.
J. Physiol. Pharmacol. 68(3):385-395, 2017
PMID:28820395
- Sharma N, Baek K, Phan H, Shimokawa N, *Takagi M.
Glycosyl chains and 25-hydroxycholesterol contribute to the intracellular transport of amyloid beta (Aβ-42) in Jurkat T cells.
FEBS Open Bio. 18;7(6):865-876, 2017.
PMID:28593141
<国際共同研究加速基金による共同研究>
- *Yamashita SI, *Kanki T.
How autophagy eats large mitochondria: Autophagosome formation coupled with mitochondrial fragmentation.
Autophagy. 2017 May 4;13(5):980-981, 2017
PMID: 28521613
- *Nomura T. *Izawa E-I.
Avian brains: insights from development, behaviors and evolution.
Dev. Growth Differ. 59(4):244-257, 2017.
PMID:28547768
- Fujita T, Higashitsuji H, Higashitsuji H, Liu Y, Itoh K, Sakurai T, Kojima
T, Kandori S, Nishiyama H, Fukumoto M, Fukumoto M, Shibasaki K, *Fujita J.
TRPV4-dependent induction of a novel mammalian cold-inducible protein SRSF5 as well as CIRP and RBM3.
Sci. Rep. 7(1):2295, 2017.
PMID:28536481
- Shimokawa N, Mukai R, Nagata M, *Takagi M.
Formation Q1 of modulated phases and domain rigidification in fatty acid-containing lipid membranes.
Phys. Chem. Chem. Phys. 19(20):13252-13263, 2017
PMID:28492655
- Kurganov E, Saito S, Saito CT, *Tominaga M.
Requirement of extracellular Ca2+ binding to specific amino acids for heat-evoked activation of TRPA1.
J. Physiol. 595(8):2451-2463, 2017
PMID:28194754
- Nishikawa H, Sasaki M, *Nishiyama KI.
Membrane insertion of F0c subunit of F0F1 ATPase depends on glycolipozyme MPIase and is stimulated by YidC.
Biochem. Biophys. Res. Commun. 487(2):477-482, 2017
PMID:28431927
- Sugio S, Nagasawa M, Kojima I, Ishizaki Y, *Shibasaki K.
TRPV2 activation by focal mechanical stimulation requires interaction with the actin cytoskeleton and enhances growth cone motility.
FASEB J. 31(4):1368-1381, 2017
PMID:28007781
<詳しくはこちら>
- Nakano M, Arai Y, Kotera I, Okabe K, Kamei Y, *Nagai T.
Genetically encoded ratiometric fluorescent thermometer with wide range and rapid response.
PLoS ONE 12(2):e0172344, 2017
PMID:28212432
- Nakamura Y, Yanagawa Y, Morrison SF, *Nakamura K.
Medullary reticular neurons mediate neuropeptide Y-induced metabolic inhibition and mastication.
Cell Metab. 25(2):322-334, 2017
PMID:28065829
<プレスリリース>(名古屋大学 日本語版)
<プレスリリース>(名古屋大学 英語版)
<詳しくはこちら>
- *Shibasaki K, Hosoi N, Kaneko R, Tominaga M, Yamada K.
Glycine release from astrocytes via functional reversal of GlyT1.
J. Neurochem. 140:395-403, 2017
PMID:27419919
- *Kimura M, Morinaka Y, Imai K, Kose S, Horton P, *Imamoto N.
Extensive cargo identification reveals distinct biological roles of the 12 importin pathways.
eLife 6:e21184, 2017
PMID:28117667
<プレスリリース>
- *Sawamura S, Shirakawa H, Nakagawa T, Mori Y, Kaneko S.
Chapter 16. TRP Channels in the Brain: What Are They There For? Neurobiology of TRP Channels
(Frontiers in Neuroscience) (Edited by Tamara Luti Rosenbaum Emir), CRC press, 295-322, 2017
書籍
2016
- Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, *Hioki H.
Differential inputs to the perisomatic and distal-dendritic compartments of VIP-positive neurons in layer 2/3 of the mouse barrel cortex.
Front Neuroanat. 10:124, 2016
PMID:28066195
- Yamashita SI, Jin X, Furukawa K, Hamasaki M, Nezu A, Otera H, Saigusa T, Yoshimori T, Sakai Y, Mihara K, *Kanki T.
Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy.
J. Cell Biol. 215(5):649-665, 2016
PMID:27903607
<プレスリリース>
- *Nishiyama KI, Tokuda H.
Novel translocation intermediate allows re-evaluation of roles of ATP, proton motive force and SecG at the late stage of preprotein translocation.
Genes Cells 21(12):1353-1364, 2016
PMID:27813233
- Kaneko T, Kaneda K, Ohno A, Takahashi D, Hara T, Amano T, Ide S, Yoshioka M, *Minami M.
Activation of adenylate cyclase-cyclic AMP-protein kinase A signaling by corticotropin-releasing factor within the dorsolateral bed nucleus of the stria terminalis is involved in pain-induced aversion.
Eur. J. Neurosci. 44(11):2914-2924, 2016
PMID:27690274
- #Okahata M, #*Ohta A, Mizutani H, Minakuchi Y, Toyoda A, *Kuhara A.
Natural variations of cold tolerance and temperature acclimation in Caenorhabditis elegans.
J. Comp. Physiol. B 186(8):985-998. 2016
PMID:27318666
- Miyake T, Nakamura S, Zhao M, So K, Inoue K, Numata T, Takahashi N, Shirakawa
H, Mori Y, *Nakagawa T, Kaneko S.
Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS.
Nat. Commun. 7:12840, 2016
PMID:27628562
<詳しくはこちら>
- Sun W, *Uchida K, Takahashi N, Iwata Y, Wakabayashi S, Goto T, Kawada T, *Tominaga M.
Activation of TRPV2 negatively regulates the differentiation of mouse brown adipocytes
Pflugers Arch. 468(9):1527-1540, 2016
PMID:27318696
- Ujisawa T, *Ohta A, Uda-Yagi M, *Kuhara A.
Diverse Regulation of Temperature Sensation by Trimeric G-Protein Signaling in Caenorhabditis elegans.
PLoS One 11(10):e0165518, 2016
PMID:27788246
- *Shimokawa N, Himeno H, Hamada T, Takagi M, Komura S, Andelman D.
Phase Diagrams and Ordering in Charged Membranes: Binary Mixtures of Charged and Neutral Lipids.
J. Phys. Chem. B 120(26):6358-6367, 2016
PMID: 27141936
- Sonoda S, *Ohta A, Maruo A, Ujisawa T, *Kuhara A.
Sperm affects head sensory neuron in temperature tolerance of Caenorhabditis elegans
Cell Rep. 16(1):56-65, 2016
PMID:27320929
DOI:10.1016/j.celrep.2016.05.078.
<詳しくはこちら>
- *Saito S, Ohkita M, Saito CT, Takahashi K, Tominaga M, *Ohta T.
Evolution of Heat Sensors Drove Shifts in Thermosensation between Xenopus Species Adapted to Different Thermal Niches
J. Biol. Chem. 291(21):11446-11459, 2016
PMID:27022021
- Takaishi M, Uchida K, Suzuki Y, Matsui H, Shimada T, *Fujita F, *Tominaga M.
Reciprocal effects of capsaicin and menthol on thermosensation through regulated activities of TRPV1 and TRPM8.
J. Physiol. Sci. 66(2):143-155, 2016
PMID:26645885
- Chiba Y, *Yamada T, Tsukita S, Takahashi K, Munakata Y, Shirai Y, Kodama S, Asai Y, Sugisawa T, Uno K, Sawada S, Imai J, Nakamura K, Katagiri H,
Dapagliflozin, a Sodium-Glucose Co-Transporter 2 Inhibitor, Acutely Reduces Energy Expenditure in BAT via Neural Signals in Mice.
PLoS One 11(3):e0150756, 2016
PMID:26963613
領域内共同研究
- Sun W, *Uchida K, Suzuki Y, Zhou Y, Kim M, Takayama Y, Takahashi N, Goto T, Wakabayashi S, Kawada T, Iwata Y, *Tominaga M.
Lack of TRPV2 impairs thermogenesis in mouse brown adipose tissue.
EMBO Rep. 17(3):383-399, 2016
PMID:26882545
<プレスリリース>
<詳しくはこちら>
- *Uchida K, Demirkhanyan L, Asuthkar S, Cohen A, Tominaga M, *Zakharian E.
Stimulation dependent gating of TRPM3 channel in a planar lipid bilayer.
FASEB J. 30(3):1306-1316, 2016
PMID:26655382
<プレスリリース>
<詳しくはこちら>
2015
- Himeno H, Ito H, Higuchi Y, Hamada T, *Shimokawa N, Takagi M.
Coupling between pore formation and phase separation in charged lipid membranes.
Phys. Rev. E 92(6):062713, 2015
PMID:26764733
- *Shibasaki K, Sugio S, Takao K, Yamanaka A, Miyakawa T, Tominaga M, Ishizaki Y.
TRPV4 activation at the physiological temperature is a critical determinant of neuronal excitability and behavior.
Pflugers Arch. 467(12):2495-2507, 2015
PMID:26250433
- Sugahara K, Shimokawa N, *Takagi M.
Destabilization of Phase-separated Structures in Local Anesthetic-containing Model Biomembranes.
Chem. Lett. 44:1604-1606, 2015
- Shimokawa N, Nagata M, *Takagi M.
Physical properties of the hybrid lipid POPC on micrometer-sized domains in mixed lipid membranes.
Phys. Chem. Chem. Phys. 17:20882-20888, 2015
PMID:26214181
太字;班員(分担研究者を含む)、下線;班員及び研究室所属メンバー、*;責任著者、#;equal contribution