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2023年09月11日

Mapping somatomotor circuits with ultrahigh field fMRI in mouse and monkey

日 時 2023年09月11日(月) 11:00 より 12:00 まで
講演者 Seong-Gi Kim
講演者所属 Center for Neuroscience Imaging Research, Institute for Basic Science; Department of Biomedical Engineering, Sungkyunkwan University Republic of Korea
場 所 明大寺1FセミナールームA/B
お問い合わせ先 竹村 浩昌 (htakemur@nips.ac.jp)
要旨 The somatomotor network is highly important for understanding the interaction between tactile and motor functions.  Anatomical somatomotor connections have been investigated by viral tracing, but its functional circuits are not well-investigated especially in primates.  Here we used whole-brain fMRI to identify the somatomotor network responding to somatosensory stimuli in anesthetized animals. Then, to separate upstream vs. downstream circuits, localized cortical regions were selectively activated or silenced. By combining fMRI with circuit manipulations, we were able to determine somatomotor circuits. In my talk, I will discuss microelectric and optogenetic stimulation, and share our recent 7T fMRI data in monkeys and 15.2T fMRI data in mice.