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2016年10月03日

1.Temporal and frontal brain areas interact to set relative reward expectation
2.Do monkeys have long-term memory?

日 時 2016年10月03日(月) 10:00 より 12:00 まで
講演者 1.Dr. Barry J Richmond
2.Dr. Richard C Saunders
講演者所属 NIMH/NIH
場 所 生理学研究所(明大寺地区)1Fセミナー室
お問い合わせ先 小松英彦(感覚認知情報研究部門 内線7861)
要旨

下記の予定で所長招聘セミナーを開催します。認知行動メカニズムの研究で有名なBarry J Richmond博士とRichard C Saunders博士が来訪されることになりセミナーをお願いしました。多数ご来聴下さい。

講演1
講演者:Dr. Barry J Richmond (NIMH/NIH)
演 題:Temporal and frontal brain areas interact to set relative reward expectation

 The choices we make about what actions to take reflect the relative values of the outcomes, with more valuable ones chosen more often than less valuable ones – or perhaps we infer which are more and less valuable from which are chosen more often. Thus, in day-to-day activity, choices are often from among several possibilities. This requires estimating the values, comparing them to other values and remembering these values for ongoing reference.
 We have examined data from behavior, single neuron recording, and tissue inactivation in rhesus monkeys, and found that the rhinal cortex in the medial temporal lobe, the orbitofrontal cortex and the lateral prefrontal cortex are all involved in setting values. We believe that the OFC is sensitive to the reward values, that the lateral PFC is sensitive to putting values from different dimensions such as reward size and delay –to-reward, and the rhinal cortex is critical for assigning/remembering the relative values of the rewards. Our data indicate that the brain areas are engaged in a dynamic interaction to allow behavior decisions based on the relative values of predicted outcomes.

 

講演2
講演者:Dr. Richard C Saunders (NIMH/NIH)
演 題:Do monkeys have long-term memory?

 The auditory cortex underlies effortless ability to discriminate and remember complex sounds, including speech.  Anatomical findings in monkeys have raised the possibility that, like the occipitotemporal visual areas, superior temporal auditory areas send highly processed stimulus quality information to downstream targets that are important for stimulus recognition. To investigate the importance of this ventral stream in auditory memory, monkeys were trained on an auditory recognition task. We found their memory performance is limited to short-term memory, and unaffected by lesions of the rhinal cortex; this is in sharp contrast to their memory performance in vision which extends to long-term memory and is severely disrupted by a rhinal lesion. These studies suggest that monkeys may be unable to store acoustic signals in long-term memory, raising the possibility that they may therefore also lack auditory working memory (WM).