Our cardiocirculatory function is mainly controlled by muscular organs composed of striated muscles (heart and skeletal muscles) and smooth muscle (blood vessels). Our group aims to elucidate the molecular mechanisms underlying transition of the muscles from adaptation to maladaptation against environmental stress (mainly hemodynamic load) multi-level techniques to evaluate cardiovascular functions (in vivo and in vitro), and work toward practical application (e.g., drug discovery and fostering). We also investigate the mechanism of muscle repair and regeneration, and aim to develop a novel therapeutic strategy for refractory diseases. In addition, we address the inclusive research to elucidate the mechanism underlying maintenance and transfiguration of cardiocirculatory homeostasis via multi-organ interactions by combining non-invasive measuring methodologies of motor functions and those cardiovascular functions.
Our laboratory has various techniques and equipments to drive the above researches.
Figure. Measuring systems for cardiovascualr functions and summary of our research using these systems
Introduce a researcher of NIPS.