| Outline |
In this lecture, I will introduce the molecular mechanisms for synaptogenesis and synaptic transmission, and the physiopathological mechanisms for synaptic disorders. First, I will overview the basic knowledge about cytoskeletons and neuronal cell adhesion molecules, which dynamically regulate the synapse formation and functions. I will also mention about the recent topic for liquid-liquid phase separation in the synapse. Furthermore, synaptic disorders induced by congenital mutations and autoantibodies against synaptic proteins will be introduced. |
